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Differences by sex in lung cancer incidence and mortality have been reported which cannot be fully explained by sex differences in smoking behavior, implying existence of genetic and molecular basis for sex disparity in lung cancer development. However, the information about sex dimorphism in lung cancer risk is quite limited despite the great success in lung cancer association studies. By adoptin
AMP-activated protein kinase (AMPK) activation is considered a useful strategy for the treatment of type 2 diabetes (T2D). It is unclear whether the expression and/or activity of AMPK in adipocytes is dysregulated in obesity. Also, the expression/activity pattern of AMPKβ isoforms, which are targets for AMPK activators, in adipocytes remains elusive. In this study we show that the two AMPKβ isofor
BackgroundMost patients with Hodgkin’s lymphoma are young and have a favourable prognosis, therefore it is of high importance to decrease the radiation doses to normal tissues received during radiotherapy. A combination of proton therapy and deep inspiration breath-hold technique (DIBH) can improve the sparing effect and thereby reduce the risk of late effects.Case presentationThe two first patien
Even more than in developing countries today, public health strategies to fight infectious disease in the past focused on the prevention of new infections by stopping their spread. These strategies were motivated by new insights into the causes of disease and the modes of transmission in the mid-nineteenth century. By combining longitudinal individual-level data on 17,000 children in a rural/semi-
While previous research has advocated the use of online sales channels as a driver for international expansion, the nature of the relationship between e-commerce and international sales is still unexplored. The purpose of this paper is to create a parsimonious model where we investigate whether, and to what extent, strategies pertaining to the geographical scope of international operations moderat
Despite a growing reliance on evolutionary theories when explaining industrial dynamics, the mechanism of selection has received limited attention. Selection is often taken for granted and conceptualised as product market competition. We go beyond this view and distinguish between different types of selection—formal and social—and consider how these lead to different entities being selected. Forma
This contribution analyses the presence of Economic History in the undergraduate study programmes of some European countries. The objective is to offer a counterpoint to the Spanish experience, which will be addressed by other papers and is also likely the most known framework for most of the participants. We look at the total offer of Economic History courses, as well as at whether they are onl
This essay introduces environmental historians to a new approach inspired by the burgeoning field of Wissensgeschichte; that is, the study of societal circulation of knowledge. It is argued that this new method can help us to better map out and analyse the emergence of modern environmentalism in society at large. To demonstrate the practical implications of the argument the essay is centred on an
Denna artikel diskuterar en ny form av snabbt expanderande praktiker från tidigt 2000-tal och som erbjuds av privata företag eller entreprenörer (lekmannaterapeuter). I fokus står självförverkligande och helande. Jag har med hjälp av verktyg från Ritual Studies valt att analysera dessa praktiker som en form av individ-centrerade riter som designas för att lindra smärta och lågt självförtroende för
