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In order to add to the existing knowledge on the complex institutional dynamics of negotiating conflicts and compatibilities in innovation processes that address societal challenges and social needs, this article scrutinizes the scientific and societal debate on the theoretical and practical application of “social innovation” by means of the concept “boundary object” linked to institutional theoryIn order to add to the existing knowledge on the complex institutional dynamics of negotiating conflicts and compatibilities in innovation processes that address societal challenges and social needs, this article scrutinizes the scientific and societal debate on the theoretical and practical application of “social innovation” by means of the concept “boundary object” linked to institutional theory

The purpose of this paper is to describe and produce a more profound understanding of how communication professionals perceive that they realize strategic communication in organizations. Another aim is to deepen the understanding of what consequences the strategic work with communication has for the co-creation of meaning in which the organization is constituted. The paper is based on a qualitativ

This paper critically scrutinizes the key success factors and tools described in the partnering literature by exploring how they are implemented in a public–private partnering collaboration. In addition to this the paper investigates to what extent these tools facilitate the relationship between the parties in a partnering process. The empirical data consist of two longitudinal case studies. Both

Aim: To define the genomic distribution and function of DNA methylation changes during human adipogenesis. Methods: We isolated adipocyte-derived stem cells from 13 individuals and analyzed genome-wide DNA methylation and gene expression in cultured adipocyte-derived stem cells and mature adipocytes. Results: We observed altered DNA methylation of 11,947 CpG sites and altered expression of 11,830

Glycogen metabolism in β-cells may affect downstream metabolic pathways controlling insulin release. We examined glycogen metabolism in human islets and in the rodent-derived INS-1 832/13 β-cells and found them to express the same isoforms of key enzymes required for glycogen metabolism. Our findings indicate that glycogenesis is insulin-independent but influenced by extracellular glucose concentr

The transnational and transmedial dimensions of media and communication throughout history have not always been adequately recognised. In this research report we propose the concept of entanglement as a means of better understanding the dynamic interconnectedness of media across semiotic, technological, institutional and political boundaries in history. Entanglement is a concept that can be employThe transnational and transmedial dimensions of media and communication throughout history have not always been adequately recognised. In this research report we propose the concept of entanglement as a means of better understanding the dynamic interconnectedness of media across semiotic, technological, institutional and political boundaries in history. Entanglement is a concept that can be employ

In this paper, we describe KOSHIK, an end-to-end framework to process the unstructured natural language content of multilingual documents. We used the Hadoop distributed computing infrastructure to build this framework as it enables KOSHIK to easily scale by adding inexpensive commodity hardware. We designed an annotation model that allows the processing algorithms to incrementally add layers of a

Accumulating evidence suggests that dysregulated glycerol metabolism contributes to the pathophysiology of obesity and type 2 diabetes. Glycerol efflux from adipocytes is regulated by the aquaglyceroporin AQP7, which is translocated upon hormone stimulation. Here, we propose a molecular mechanism where the AQP7 mobility in adipocytes is dependent on perilipin 1 and protein kinase A. Biochemical an

Experimental studies have suggested an atheroprotective role of interleukin (IL)-5 through the stimulation of natural immunoglobulin M antibody expression. In the present study we show that there are no associations between baseline levels of IL-5 and risk for development of coronary events or stroke during a 15.7 ± 6.3 years follow-up of 696 subjects randomly sampled from the Malmö Diet and Cance

Today’s society promises that people with disabilities can access anything, but in practice there are numerous obstacles, and the ways in which people deal with them can be easily missed or taken for granted by policy makers. This article draws on a project in which researchers ‘go along’ people with disabilities in Sweden who demonstrate and recount accessibility troubles in urban and digital set

Increasing application of strategic environmental assessment (SEA) of land-use plans has been accompanied by concerns about their quality. This paper suggests a tool for the systematic evaluation of the quality of SEA reports, based on criteria derived from formal SEA provisions, including the draft European Union SEA Directive, general objectives and principles of SEA and reports of good SEA prac