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This paper presents a methodology with the purpose of modeling and simulating outdoor temperature and relative humidity (vapor concentration) related to moisture exposure on timber structures. The methodology is based on time-series analysis with recorded meteorological data used as input. In situations where recorded data is missing or consists of limited sequences, this methodology offers the po
Creep and shrinkage are two major problems to be discussed in concrete design. Basic creep is studied during constant loading, temperature and moisture conditions, i.e. no exchange of moisture takes place to or from the specimen during the test period. In this paper an experimental and numerical study of basic creep of High Performance Concrete (HPC) is outlined. For this purpose cylinders and cub
When analysing new types of sewage systems, knowledge is needed on the composition of the different wastewater fractions. The computer model URWARE, developed from the model ORWARE, is intended to analyse and compare different wastewater system structures, e.g. to compare wastewater systems where urine and/or faeces are source separated with conventional wastewater systems, where the different was
Aim: To define the genomic distribution and function of DNA methylation changes during human adipogenesis. Methods: We isolated adipocyte-derived stem cells from 13 individuals and analyzed genome-wide DNA methylation and gene expression in cultured adipocyte-derived stem cells and mature adipocytes. Results: We observed altered DNA methylation of 11,947 CpG sites and altered expression of 11,830
Glycogen metabolism in β-cells may affect downstream metabolic pathways controlling insulin release. We examined glycogen metabolism in human islets and in the rodent-derived INS-1 832/13 β-cells and found them to express the same isoforms of key enzymes required for glycogen metabolism. Our findings indicate that glycogenesis is insulin-independent but influenced by extracellular glucose concentr
The transnational and transmedial dimensions of media and communication throughout history have not always been adequately recognised. In this research report we propose the concept of entanglement as a means of better understanding the dynamic interconnectedness of media across semiotic, technological, institutional and political boundaries in history. Entanglement is a concept that can be employThe transnational and transmedial dimensions of media and communication throughout history have not always been adequately recognised. In this research report we propose the concept of entanglement as a means of better understanding the dynamic interconnectedness of media across semiotic, technological, institutional and political boundaries in history. Entanglement is a concept that can be employ
In this paper, we describe KOSHIK, an end-to-end framework to process the unstructured natural language content of multilingual documents. We used the Hadoop distributed computing infrastructure to build this framework as it enables KOSHIK to easily scale by adding inexpensive commodity hardware. We designed an annotation model that allows the processing algorithms to incrementally add layers of a
Accumulating evidence suggests that dysregulated glycerol metabolism contributes to the pathophysiology of obesity and type 2 diabetes. Glycerol efflux from adipocytes is regulated by the aquaglyceroporin AQP7, which is translocated upon hormone stimulation. Here, we propose a molecular mechanism where the AQP7 mobility in adipocytes is dependent on perilipin 1 and protein kinase A. Biochemical an
Recent literature stresses the increasing importance of global innovation networks as a new mechanism to organize innovation across geographical space. This paper investigates if institutional diversity, defined at the level of the firm, influences firms’ engagement in GINs. Institutional diversity provides knowledge about the institutional context of other countries, increased capabilities to dea
