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Online evaluations are one of the most important innovations in tourism in recent years, often combining a review/rating (business-specific evaluation) and a ranking (inter-business comparison). As online reputation determines economic success, tourism managers may be tempted to manipulate online content. This paper presents the results from a qualitative study involving 20 hotel managers in south
The performance of new firms is important for economic development but research has produced limited knowledge about the key relationships among growth, profitability, and survival for new firms. Based on evolutionary theory, we develop a model about how new firms resolve uncertainty about their ability to prosper in a market by monitoring changes in profitability. Our model predicts selection pre
This article investigates the gender aspects of technology use in the innovation system. The generic question is: to what extent is it necessary to distinguish between women and men in the use of technology? A second question is: if gender-specific differences do exist, to what extent is the innovation system capable of utilizing experiences from women as well? The article examines two sets of tec
Insights from prospective, longitudinal studies of individuals at risk for developing type 1 diabetes have demonstrated that the disease is a continuum that progresses sequentially at variable but predictable rates through distinct identifiable stages prior to the onset of symptoms. Stage 1 is defined as the presence of β-cell autoimmunity as evidenced by the presence of two or more islet autoanti
This paper contributes to an ongoing debate on the syntactic status of oblique subject-like NPs in the ‘impersonal’ construction (of the type me-thinks) in Old Germanic. The debate is caused by the lack of canonical subject case marking in such NPs. It has been argued that these NPs are syntactic objects, but we provide evidence for their subject status, as in Modern Icelandic and Faroese. Thus, w
The progression of diabetes is accompanied by increasing demand to the beta-cells to produce and secrete more insulin, requiring complex beta-cell adaptations. Functionally-active and ubiquitous non-coding RNAs (ncRNAs) have the capacity to take part in such adaptations as they have been shown to be key regulatory molecules in various biological processes. In the pancreatic islets, the function of
Coronary disease risk increases inversely with high-density lipoprotein (HDL) level. The measurement of the biodistribution and clearance of HDL in vivo, however, has posed a technical challenge. This study presents an approach to the development of a lipoprotein MRI agent by linking gadolinium methanethiosulfonate (Gd[MTS-ADO3A]) to a selective cysteine mutation in position 55 of apo AI, the majo
Type 2 diabetes (T2D) develops due to insulin resistance and impaired insulin secretion, predominantly in genetically predisposed subjects exposed to nongenetic risk factors like obesity, physical inactivity and ageing. Emerging data suggest that epigenetics also play a key role in the pathogenesis of T2D. Genome-wide studies have identified altered DNA methylation patterns in pancreatic islets, s
Purpose – The purpose of this paper is to look more closely at the residents’ attitude to individual heat metering and charging systems (IMC) of multi-family dwellings in residential properties, and to evaluate the tenant’s perception of IMC and how it may affect the continued expansion of such systems. Design/methodology/approach – The research in this paper is based on a questionnaire and interv
Sustainability science needs approaches that allow for the integration of knowledge across disciplines and scales. This paper suggests an approach to conceptualize problems of unsustainability by embedding the Drivers-Pressure-State-Impact-Response (DPSIR) scheme within a multi-level institutional framework represented by Hagerstrand's system of nested domains. The proposed taxonomy helps to decip
The analytical framework of regional innovation systems highlights the systemic nature of regional economies and the need for policy coordination within regions. Coordination presupposes an understanding of the underlying problems that may act as barriers to regional development. Three generic problems facing regions are: lack of resources (e.g. human and financial capital), negative lock-in (e.g.
The increasing demand for human egg cells has led to reproductive tourism and a transnational egg trade. The activity flourishes due to poverty and criminality, as well as medical needs (infertility) and cultural needs (the dream of parenthood). Other factors are fundamental concepts, such as the view of the body as an object of utility and value. This article aims to go behind the normative discu
The negative effect of agricultural intensification on bumblebee populations is thought to partly be caused by loss of food plants, for example because of increased field size and concomitant loss of non-crop field borders and their nectar and pollen plants. Earlier studies have focused on how loss of foraging resources affects colony growth and thereby abundance of workers and sexual reproduction
