Background and Objectives: The prevalence of back pain and its effect on function and health-related quality of life across three levels of lower limb amputation secondary to trauma or tumour was studied. Study design: Cross-sectional survey. Methods: Forty-six lower limb amputees, aged 19-78 years, participated. The Roland Morris disability questionnaire (RMDQ) and the short form 36 health survey

This article aims to highlight how literary value is constructed today: how it is created and negotiated. It seeks to develop a perspective that considers the manifold and complex value­negotiation process. In accordance with Barbara Herrnstein Smith, the article argues that literary value is generated by a constant and continuous series of negotiations between production and sale: the institution

Two isolated mosasaur teeth, one from the upper Campanian of Piotrawin, the other from the upper Maastrichtian at Nasilow (Wisla River valley, central Poland), recently described as Plioplatecarpinae sp. A and Plioplatecarpinae sp. B, respectively, are reassigned to the tylosaurine genus Hainosaurus Dollo, 1885. The present record thus adds to the list of Hainosaurus species known to date from els

Breast cancer is a rare disease in men, affecting less than 0.1% of the male population. Two heritable gene defects have been associated with a predisposition to male breast cancer development, ie., germ-line mutations in the breast cancer susceptibility gene BRCA2 and the androgen receptor (AR) gene. In this study, the entire coding regions of BRCA2 and AR were screened for mutations in 34 consec

Background and Purpose-Patients treated with oral anticoagulants (ACs) have an increased risk of intracerebral hemorrhage (ICH), which is more often fatal than spontaneous ICH. Options to reverse the AC effect include intravenous administration of vitamin K, plasma, and coagulation factor concentrate. However, the optimal management of AC-related ICH has not been determined in any randomized trial

This paper is a discussion of theory and methods used in intrasite spatial analysis - the analysis of "living floors". Processes in the formation of the archaeological record such as abandonment, discard, loss, and caching, are discussed. There is also some investigation into factors which may disturb or obscure patterning on an occupation site. Examples to illustrate the discussion are taken from

Rational politics requires the ability to predict the future and to evaluate the possible effects of political decisions. The article evaluates various attempts to establish functional arguments for maximal linguistic differentiation and demonstrates the difficulties with such arguments. If there are no objective arguments, we have to rely on feelings, which leaves us with a politics based on powe

Context: SHBG regulates free sex steroid levels, which in turn regulate skeletal homeostasis. Twin studies have demonstrated that genetic factors largely account for interindividual variation in SHBG levels. Glucuronidated androgen metabolites have been proposed as markers of androgenic activity. Objective: Our objective was to investigate whether polymorphisms in the SHBG gene promoter [(TAAAA)(n

Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.

AIMS/HYPOTHESIS: Young adults in the early stages of their participation in the labour market may be particularly vulnerable to the effects of onset of a chronic disease. Our aim was to quantify the consequences of the onset of type 1 diabetes in young adults on annual earnings, using individual-level longitudinal data before and after the onset of diabetes. METHODS: The Econ-DISS database contain