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In recent years, a growing body of research has studied the effects of social network sites on various aspects of politics. However, little attention has been spent on how social network sites are used internally in political parties, and how they affect the perceived tension between the hierarchical structure of the political party and the network-based communication becoming more common and tech
It is argued that we live in a post-industrial society with a transition from the production of goods to services. It is also said we live in a knowledge economy where creation, distribution, use and manipulation of information are significant activities (Dahlbom, 2003). The word industrial has a connotation of mass-production of products and, logically also industrial design has this connotation.
The increased popularity of and attention for innovation based regional growth and development has, among other things, brought forward the importance of universities in regional innovation systems (RIS). The triple helix literature especially underscores the value of increased interaction and interdependence between universities – industry – government in modern, knowledge-based economies by accl
To be able to predict the strength of climate change and its consequences for mankind, it is of major importance to understand the contemporary greenhouse gas exchange of the terrestrial biosphere, as well as its response to changes in climate. To achieve such understanding both descriptive studies and manipulation experiments are required. Northern peatlands represent an important ecosystem type
Background: Despite the compelling scientific evidence on the superiority of stroke unit care, far from all acute stroke patients have access to stroke unit care. In congruence with what has been observed when other new methods are introduced in health care, we hypothesized that there has been an inequality in the buildup phase of stroke units but that the gradients between patient groups have dec
The overall aim of this thesis is to examine how walking as a transport mode is constructed in the planning realm, affected by the built environment and perceived by the individual. This aim is related to the following research questions: (1) How are pedestrians and walking understood, constructed and perceived in the planning context? (2) How does individual traits and the built environment affec
Energy users who don’t participate in efficiency and conservation programmes despite ongoing outreach are often referred to as ‘Hard-to-Reach’ (HTR). These individuals or organisations can include, e.g., low income or vulnerable households; renters; and small businesses. More effectively engaging HTR audiences is key to ensuring everyone benefits equitably from low-carbon energy transitions and re
The concept of digital discretion has been defined as information and communication technology (ICT) influencing or replacing the professional judgment of civil servants. Studies within digital discretion has mainly taken a civil servants perspective focusing on how ICT can constrain or enable discretionary practices (Bovens and Zouridis 2002; Wenger and Wilkis 2009; Wihlborg et al. 2016) have inv
The burden of cardiometabolic diseases is increasing worldwide. Early detection of high-risk individuals is essential for appropriate diagnosis, better treatment outcomes, quality of life and lower health related costs. Aims: The overall aim of this thesis is to investigate the possible associations between plasma proneurotensin (Pro-NT) and risk of cardiovascular disease (CVD), type 2 diabetes (T
BACKGROUND: Patients with oesophageal and gastric cancer have a low likelihood of being cured and suffer from a broad spectrum of symptoms and problems that negatively affect their quality-of-life (QOL). Although the majority (67-75%) of patients at the time of diagnosis suffer from an incurable disease, research has primarily focused on the pre- and postoperative phase among patients treated with
Expansions of innovation policies have been paralleled with an increase in the evaluations of such policies. Yet, there are few systematic evaluations of how such evaluations are conducted, by whom, and their overall conclusions. We analyze 110 evaluations of innovation policy in Sweden from 2005 to 2019. Our findings show that the majority of these evaluations are positive, about one-third are ne
Differential expression of microRNAs (miRNAs) is observed in many diseases including type 2 diabetes (T2D). Insulin secretion from pancreatic beta cells is central for the regulation of blood glucose levels and failure to release enough insulin results in hyperglycemia and T2D. The importance in T2D pathogenesis of single miRNAs in beta cells has been described; however, to get the full picture, h
During inflammation, cellular glucose uptake and glycolysis are upregulated to meet an increased energy demand. For example, keratinocyte glycolysis is essential for progression of psoriasis. Therefore, understanding the regulation of glucose metabolism in keratinocytes is of importance. Here, we show that the pro-inflammatory cytokines IFNγ and TNF together rapidly induce glucose uptake, glycolys
