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Studies were conducted to investigate the role of macula densa (MD)-derived nitric oxide (NO) in regulation of the glomerular filtration (GFR) through the tubuloglomerular feedback (TGF) mechanism. Immunocytochemical localization of the neuronal isoform of NO synthase (NOS) in the kidney showed that this isoform was exclusively located in MD cells. Whole kidney clearance measurements of GFR and mi
There is uncertainty of how external factors will affect property development costs. Clarification and mapping of these external factors and how they impact the property development process is needed in order to gain insights into total development costs in the early stages of a project. The objective of the research reported in this paper is to understand the impact of external factors, for examp
The term ‘strategic use of procurement’ indicates that the procurement (also referred to as sustainable procurement) is about more than just saving money. Other important interests such as social and environmental considerations can be promoted through public procurement. Procurers can, according to newly proposed Directives on public procurement, make better use of public procurement in support o
Electrocochleography (ECoG) is an objective method to evaluate cochlear electrophysiology. The recordings are considered to reflect the mechano-electric processes of the cochlea, and can indicate the presence of suspected endolymphatic hydrops. The aim of the present thesis was to investigate the value of transtympanic (TT) ECoG in the clinical diagnosis and management of Menière´s disease. The tr
ANCA-associated systemic vasculitis (AASV) is a group of inflammatory disorders, characterized by inflammation and necrosis of blood vessels and frequently granuloma formation. Patients with AASV make autoantibodies, so called ANCA, against proteins present in the granules of neutrophils and monocytes, mainly proteinase 3 (PR3) and myeloperoxidase (MPO). Clinically, disease progression is characte
A main purpose of this thesis was to develop a model of leadership style named Generative Learning Management (GLM), thought to influence goal-oriented interpersonal creativity in organizations, and to test this model. Creativity is a complex consisting of both novelty and usefulness and it is a general mental ability that is determined by the interplay between different regions in a normally func
This book brings into question the dichotomies inherent in the sociology of law. It is a journey in search of a method capable of taking us beyond the theoretical limitations imposed on socio-legal research by sharply defined divisions such as “law on the books” and “law in action”, “formal” and “informal law”, “facts” and “norms”, “form” and “substance”, “internal” and “external” legal cultures o
The focus of the presentation is on the individual’s comprehension of “citizenship”. Study and analysis of citizenship concerns a person’s co-operative interaction with various physical and social surroundings as well as the cognitive integration of these surroundings. A person can achieve this integration through development of his abilities of judgement. Thus the aim is to make apparent the kind
Asylum seekers are often assigned to a locality in their host country directly upon arrival based on some type of uninformed dynamic matching system which does not take the background of the asylum seekers into consideration. This paper proposes an informed, intuitive, easy-to-implement and computationally efficient dynamic mechanism for matching asylum seekers to localities. This mechanism can be
Accommodation businesses are increasingly dependent on a limited number of reservation platforms. A significant feature of these platforms is guest evaluations, which are transformed into ratings and rankings. As the positioning of the business in comparison to competitors determines customer demand, accommodation managers have considerable interest in maintaining or improving their online reputat
In this paper, we will present some of our findings from a study conducted on legislative measures related to the online infringement of intellectual property rights commissioned by the European Union Intellectual Property Office (EUIPO) on legislative measures related to online intellectual property rights infringements. The present summarizes the mapping the existing legislative national measur
Background: Abdominal obesity is linked to cardiovascular diseases in type 1 diabetes (T1D). The primary aim was to explore associations between abdominal obesity and cardiovascular complications, metabolic and inflammatory factors. The secondary aim was to explore whether achieved recommended treatment targets differed between the obese and non-obese participants. Methods: Cross sectional study o
We used eddy-covariance (EC) measurements of net ecosystem exchange (NEE) above canopy to assess the effects of thinning on CO2 fluxes at the ICOS Sweden site Norunda in central Sweden. This forest site consists of mixed pine and spruce stands approx. 100 years old. The thinning during late autumn 2008, performed in a semicircle from the mast extending 200m outwards harvested about 25% of the volu
Quinoline-3-carboxamides (Q substances) are small molecule compounds with anti-inflammatory properties. In this study, we used one of these substances, Paquinimod, to treat a novel model for chronic liver inflammation and liver fibrosis, the NOD-Inflammation Fibrosis (N-IF) mouse. We show that treatment of N-IF mice significantly reduced inflammation and resulted in the regression of fibrosis, eve
