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Systemic lupus erythematosus (SLE) is an autoimmune disease where improperly cleared apoptotic cells and neutrophil extracellular traps (NETs) induce an autoimmune response. Complement is crucial to prevent SLE by tailoring immune responses and opsonizing dead cells but may also induce inflammation and tissue damage once the disease is initiated. Complement C1q binds to apoptotic cells and ensures
According to Polarity Theory, all ideologies are fundamentally polarized by a conflict between Humanism, which idealizes and glorifies humanity, and Normativism, which portrays human goodness and worth as contingent upon conformity and achievement. Humanism and Normativism have, however, turned out to be distinct worldviews rather than opposite ends of a single bipolar continuum. Introducing a hie
The North Atlantic region has experienced significant climate fluctuations during the Holocene. It has been shown that these fluctuations affected the terrestrial environment in Iceland, including its glaciers and ice caps. However, the full Holocene development of Icelandic glaciers, including the large Vatnajökull ice cap and its outlet glaciers, is not fully known. In this thesis, a sediment se
Although high-throughput studies of gene expression have generated large amounts of data, most of which is freely available in public archives, the use of this valuable resource is limited by computational complications and non-homogenous annotation. To address these issues, we have performed a complete re-annotation of public microarray data from human skeletal muscle biopsies and constructed a m
The overall aim of this thesis was to deepen the understanding of work ability by analyzing how different health professionals experience and perceive work ability and assessments of work ability, and also by analyzing rehabilitation outcomes that are related to work ability. The focus has been on musculoskeletal disorders with associated psychosocial factors. Method. The general approach was indu
This thesis concerns the role of disability and assistive devices in everyday life among persons with, for instance, impairments related to mobility (e.g. wheelchair users) and bodily shape and configuration (e.g. dysmelia). Assistive devices are seen as both includators (assisting participation and emancipation) and excludators (limiting participation, restraining empowerment, and stigmatizing).
Det är en obehaglig realitet att i Sverige döms oskyldiga personer för brott de inte har begått. Statistiskt sett händer det sannolikt mycket sällan men över en tillräcklig lång tidsrymd är det oundvikligt. Detta trots den lagstadgade oskyldighetspresumtionen som ger den som är misstänkt för ett brott rättigheten att betraktas som oskyldig till dess att motsatsen har bevisats. Högsta domstolen h
Dead wood is a key element in forest ecosystems and a wide range of organisms are dependent on this substrate for development and reproduction. Saproxylic beetles are important decomposers of dead wood and serve as food for many organisms. Due to the significant forestry-related decrease of dead wood in rural areas, many species of saproxylic beetles are considered threatened. Thus, other spaces h
Introduction: Cancer is classified into several stages, being more difficult to cure in later stages. Thus, early detection is important. This project aims to help the development of a non-invasive method for early cancer detection using hair samples. Background: Isotopes are known to leave a temporary and geographical signature in different samples. Capillon Analytics AB uses isotopes to detect c
I proposition 2025/26:246 föreslår regeringen att straffbarhetsåldern ska sänkas till 13 år för vissa allvarliga brott. Förslaget innebär att barn i 13–14-årsåldern ska kunna dömas till fängelse. Reformen motiveras huvudsakligen av den ökade gängrelaterade brottsligheten och att allt yngre barn involveras i grova våldsbrott. Syftet med uppsatsen är att analysera om lagförslaget om fängelse för bar
DAC7-direktivet utgör en ändring av rådets direktiv 2011/16/EU om admi-nistrativt samarbete i fråga om beskattning och trädde i kraft den 1 januari 2023. Det övergripande syftet med DAC-direktiven i allmänhet är att bekämpa skattebedrägeri och skatteundandraganden samt att säkerställa en rättvis be-skattning inom unionen. DAC7-direktivet fokuserar på berörda verksamheter som bedrivs av säljare viThe DAC7-Directive constitutes an amendment to Council Directive 2011/16/EU on administrative cooperation in the field of taxation and entered into force on 1 January 2023. The overarching purpose of the DAC directives in general is to combat tax fraud and tax evasion, as well as to ensure fair taxation within the Union. The DAC7-Directive focuses on relevant activities carried out by sellers thro
I takt med utvecklingen av AI-genererad media, har allmänhetens uppfattning om sådant innehåll förändrats. Studier visar att innehåll som märks som AI genererat interageras mindre med jämfört med innehåll märkta som mänskligt skapat. Mot denna bakgrund undersöker uppsatsen eventuella metoder för att verifiera att innehåll är skapat av en människa, i synnerhet ifall rätten till namngivelse kan fungWith the rise of AI generated media, a shift in the audience perception of AI generated content has taken place, where studies show that content which is labelled as AI will be less interacted with compared to human labelled content. The thesis therefore examines possible methods for verifying human made content, in particular, whether copyright’s right of attribution can act as a veri-fier for hu
Fastighetsköp präglas av betydande ekonomiska värden och ett omfattande regelverk, där jordabalkens strikta formkrav syftar till att säkerställa rättssäkerhet och eftertänksamhet. Samtidigt sker avtalsförhandlingar i svensk rätt som utgångspunkt på egen risk, vilket innebär att kostnader och dispositioner som vidtas före ett bindande avtal normalt inte ersätts om affären inte fullföljs. Denna ordn
