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The analytical and clinical validity of AI algorithms to score TILs in TNBC : can we use different machine learning models interchangeably?

Background: Pathologist-read tumor-infiltrating lymphocytes (TILs) have showcased their predictive and prognostic potential for early and metastatic triple-negative breast cancer (TNBC) but it is still subject to variability. Artificial intelligence (AI) is a promising approach toward eliminating variability and objectively automating TILs assessment. However, demonstrating robust analytical and p

Shared reading och läsengagemang i gymnasieskolans SVA-undervisning

Det här kapitlet fördjupar förståelsen av elevers uppfattningar om läspraktiken shared reading (SR) som ett sätt för dem att utveckla sitt läsengagemang. I kapitlet redovisas en tematisk analys av en fokusgrupp med sju elever i gymnasieskolan som deltagit i sex SR-lektioner inom ramen för SVA1 på ett yrkesprogram. Resultatet relateras till en enkät om deras språkliga bakgrund och läsvanor samt en

Exploring the link between self-rated poor oral health and cardiovascular risk : a cross-sectional study using SCORE2

Background: Poor oral health is associated with several non-communicable diseases including cardiovascular disease. There are also well-known associations between lifestyle habits, cardiovascular disease, and oral health. In Europe, SCORE2 is a recommended instrument for assessing an individual's risk of a cardiovascular event within 10 years. However, no previous studies have examined the associa

Technological competencies and firm performance : analyzing the importance of internal and external competencies

In this paper, we analyze the relationship between technological competencies (TC) and firm performance. Theoretically, the importance of TC is well established and widely accepted. Therefore, it is surprising that a number of empirical studies have been unable to confirm a substantial positive relationship between TC and firm performance. We identify two major reasons for this: [i] affected by th

Lecticans in Vascular Remodeling of the Pulmonary and Fetal Circulation : Implications for Children with End-Stage Heart Disease

Introduction: Elevated pulmonary vascular resistance (PVR) is observed in both physiological and pathological states. Pulmonary hypertension (PH) is a condition associated with significant morbidity and mortality in neonates and children and curative pharmacotherapy is lacking in most cases. In utero, a high PVR allows for blood to bypass the lungs through the open ductus arteriosus (DA). Vascular