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Neurotensin is released from the gut after fat intake and has a role in appetite regulations. Proneurotensin is a stable fragment of the neurotensin precursor hormone and fasting plasma proneurotensin levels have shown to be significantly associated with the development of cardiovascular disease in middle aged participants of the Malmö Diet and Cancer Study. Here, we aimed at replicating the initi
Autophagy has emerged as a cell survival mechanism critical for cellular homeostasis, which may play a protective role in atherosclerosis. ATG16L1, a protein essential for early stages of autophagy, has been implicated in the pathogenesis of Crohn's disease. However, it is unknown whether ATG16L1 is involved in atherosclerosis. Our aim was to analyze ATG16L1 expression in carotid atherosclerotic p
Thiazide diuretics have been recommended as a first-line antihypertensive treatment, although the choice of 'the right drug in the individual essential hypertensive patient' remains still empirical. Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment. Pharmacogenomics could be a useful tool to pinpoint gene varian
Interleukin-19 (IL-19) is a putative Th2, anti-inflammatory interleukin. Its expression and potential role in atherogenesis are unknown. IL-19 is not detected in normal artery and is expressed to a greater degree in plaque from symptomatic versus asymptomatic patients, suggesting a compensatory counter-regulatory function. We tested whether IL-19 could reduce atherosclerosis in susceptible mice an
Accident risk in adverse conditions (wet/slippery road, darkness) increases drastically and speed adaptation in these conditions is often inappropriate. The safety potential of more appropriate speeds in these situations is high. Appropriate highest speeds in different conditions are discussed. A system, which limits the maximal speed of the vehicle in the actual situation (on wet/slippery road, a
Vaccine hesitancy (VH) is an issue for healthcare students, influenced by safety concerns and misinformation. The need for better communication training and understanding sociocultural factors in VH was highlighted in a European University Alliance seminar. Practical exercises like simulation role-playing, interprofessional collaboration, and digital literacy may improve vaccine education.
This article examines how the potato is used as a crisis strategy and future practiceby a group of actors from a youth education center in Skåne, with connections to alternativeagricultural movements, hereunder among others the permaculture movementand the grassroots movement Potatisuppropet. The article is a derivative effectof the dissertation project, Living Alternative Futures: Mobilising thro
Multiword expressions (MWEs) are common word combinations which exhibit idiosyncrasies in various linguistic levels. For various downstream natural language processing applications and tasks, the identification and discovery of MWEs has been proven to be potentially practical and useful, but still challenging to codify. In this paper we investigate various, relevant to MWE, resources and tools for
