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The ongoing environmental crisis and the growing socio-economic disparities between different population groups are among the most significant challenges facing humanity. These problems are rooted in unsustainable consumption patterns, particularly in the more affluent societies worldwide. We, therefore, need to change existing consumption patterns, which is a considerable challenge. A sustainable
Regional studies often treat the region as a sub‑national unit, and it spans from neighbourhoods to cross‑border macro‑regions. In Asia, this elasticity is intensified by language. Words that look equivalent on paper rarely carry identical histories, politics, or scales. This short piece reflects on the Chinese notion of quyu (区域) and how it travels between domestic and international contexts, see
Wolcott-Rallison syndrome is a rare genetic syndrome of neonatal diabetes, liver failure, and growth retardation. We present a case with a EIF2AK3 p.(Arg902Ter) mutation, additionally complicated by hypothyroidism, impaired renal function, and exocrine pancreas insufficiency, focusing on clinical management. For its optimization, thorough care of multiple organ systems is needed.
Diabetes mellitus invariably involves impaired regulation of insulin secretion from pancreatic β cells, as a result of unfavourable environmental influences in combination with aberrant expression of risk genes at either the transcriptional or the translational level. A recent report in Nature Metabolism explores a novel role of mRNA methylation in β-cell function and suggests that its downregulat
Total internal reflection fluorescence (TIRF) microscopy is a powerful method that allows examination of plasma membrane close events in real time. The last decade, the method has successfully been used to explore GLUT4 translocation in adipocytes. Here, we describe the procedure for studying GLUT4 trafficking using TIRF microscopy in isolated primary adipocytes.
The fate of the Masurian Lutherans in eastern Poland is one of the tragedies of modern Europe. This chapter monitors the various, and often contradictory, attempts to transform a group that often escaped attempts at cultural and political classification. During the post-WWII era, various efforts to support this group were made by the part of European co-religionists. In this chapter is found a fir
Putins invasion av Ukraina var – till skillnad från vad vissa menat – högst väntat och Putins agerande är i linje med den ryska säkerhetspolitiska strategin. Putin är varken galen eller oförutsägbar. Det är också för tidigt att säga att den ryska invasionen är misslyckad eftersom att mycket tyder på att den ryska strategin går ut på att utmatta motståndaren. Det skriver statsvetaren Ardavan KhoshnPutin's invasion of Ukraine was - contrary to popular belief - highly anticipated and Putin's actions are in line with Russia's security policy strategy. Putin is neither crazy nor unpredictable. It is also too early to say that the Russian invasion has failed because there are many indications that the Russian strategy is to exhaust the opponent. This is what political scientist Ardavan Khoshnood
