Sökresultat

Coastal eutrophication by nutrient fluxes from agricultural land to marine recipients is presently com- bated by measures such as the implementation of watershed-scale wetland creation programs aimed at nitrogen removal. Such created agricultural wetlands – termed ‘nitrogen farming wetlands’ (NFWs) – receive nitrogen (N) loads predominantly as nitrate, facilitating N removal by denitrification. Ho

BACKGROUND: Pervasive refusal syndrome (PRS) is a rare but severe condition, characterised by social withdrawal and a pervasive active refusal in terms of eating, mobilisation, speech and personal hygiene. PRS has been proposed as a new diagnostic entity in child and adolescent psychiatry, although the diagnostic criteria are debated. In the past 10 years there has been an increase in PRS symptoms

The X chromosome (chrX) represents one potential source for the "missing heritability" for complex phenotypes, which thus far has remained underanalyzed in genome-wide association studies (GWAS). Here we demonstrate the benefits of including chrX in GWAS by assessing the contribution of 404,862 chrX SNPs to levels of twelve commonly studied cardiometabolic and anthropometric traits in 19,697 Finni

The comparative performance of existing models for prediction of type 2 diabetes across populations has not been investigated. We validated existing non-laboratory-based models and assessed variability in predictive performance in European populations.

Background/Objective: Previous studies have found that ethnicity influences glycemic control. We hypothesized that differences between Nordic and non-Nordic patients are less pronounced for children with type 1 diabetes in high incidence countries in Northern Europe. Research design and methods: We investigated patients aged 0-15 yr in national pediatric registers in Denmark (D), Iceland (I), Norw

The extreme pressure resulting from modern-day disasters in terms of severe shortages of resources, mass casualties, infrastructure breakdown, large-scale damage and their impact necessitate coordination between all the agencies involved in disaster response. Better coordination in international disaster response operations will make them more effective in organizing the different phases of relief

The use of (U-Th)/He thermochronometry in old slowly cooled terranes has long been debated. Hence, studies of natural setting are needed to verify the expected diffusivity behaviour of helium. Our results demonstrate that the (U-Th)/He method can be applicable to samples older than 200 Ma, and that available helium diffusion models can reproduce the results obtained from the age-vs.-depth trends.

Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in which the risk of disease is influenced by complex genetic and environmental contributions. Alleles of HLA-DRB1, IRF5, and STAT4 are established susceptibility genes; there is strong evidence for the existence of additional risk loci. Methods We genotyped more than 500,000 single-nucleotide polymorphisms (SNPs)

PURPOSE: Gitelman's syndrome (GS) is an inherited autosomal recessive disorder due to loss of function mutations in the SLC12A3 gene encoding the Na-Cl co-transporter (NCCT), the target of thiazide diuretics. The defective function of the NCCT, which normally is expressed in the apical membrane of the distal convolute tubule in the kidney, leads to mild hypotension, hypokalemia, hyperreninemic hyp

Background: Long-term frozen storage may alter the results of prostate-specific antigen (PSA) measurements, mainly because of degradation of free PSA (fPSA) in vitro. We compared the effects of long-term storage on fPSA, total PSA (tPSA), and complexed PSA (cPSA) in serum vs EDTA-plasma samples. Methods: We measured fPSA and tPSA concentrations in matched pairs of archival serum and EDTA-plasma sa