Sökresultat

Filtyp

Din sökning på "swedish" gav 93814 sökträffar

Neuronal and glial differentiation of expanded neural stem and progenitor cells; in vitro and after transplantation.

In this thesis we have used cells dissected from the lateral ganglionic eminence (LGE), the medial ganglionic eminence (MGE), and the cortical primordium of the embryonic mouse forebrain. The tissue was dissected from either i) wild-type mice, ii) green fluorescent protein (GFP)-, or iii) Gtv-a-expressing transgenic mice, and subsequently grown and expanded in vitro using two different protocols.

Svensk universitetsgrammatik för nybörjare. Övningar med facit och kommentarer

Boken innehåller praktiska övningar på moment inom olika delar av grammatiken: morfologi och ordklasser, ordbildning, syntax och språklig variation. Till övningarna finns facit med kommentarer. Kategoriseringarna och användningen av termer bygger på läroboken Svensk universitetsgrammatik för nybörjare, som i stort behandlar samma stoff. Övningsboken fungerar dock oberoende av läroboken, eftersom v

Reading achievement : Its relation to home literacy, self-regulation, academic self-concept, and goal orientation in children and adolescents

The studies in this doctoral thesis investigated how home literacy, self regulation, academic self-concept, and goal orientation influence reading ability. Study 1 investigated the effect of family-based prerequisites, reading attitude, and self-regulated learning on reading ability. Students (n= 4,018) in the eighth grade answered the IEA reading literacy test and the SRLQ. Structural Equation Mo

On the Role of the Tumor Suppressor p53 in Leukemic Cell Differentiation

Leukemic cells suffer from an impaired ability to differentiate due to inherited or acquired genetic lesions. These genetic changes can sometimes be bypassed with various compounds both in vitro, and, more rarely, in vivo, thus inducing terminal differentiation of the leukemic cells. Differentiation of both leukemic and normal hematopoietic cells is believed to be intimately coupled to cell cycle

Characterization of the perturbed differentiation in neuroblastoma, aided by the analysis of normal sympathetic nervous system development

Neuroblastoma is a pediatric tumor derived from cells in the sympathetic nervous system. In an attempt to explain the heterogeneous clinical behavior of neuroblastoma tumors, neuroblastomas have been characterized with regard to their degree of sympathetic differentiation. Their expression of genes and proteins that regulate normal sympathetic development and cell cycle/cell death regulators was a

Prepositionernas grammatik i SAOB

En genomgång av hur de grammatiska delarna av ordboksartiklar om prepositioner har behandlats terminologiskt i Svenska Akademiens grammatik (1893–).

C4b-binding protein : studies on its interactions with C4b, protein S and serum amyloid P component

C4b-binding protein (C4BP) is an acute-phase plasma glycoprotein which regulates the complement system through its affinity for C4b. In addition, C4BP binds to the anticoagulant protein S and to serum amyloid P component (SAP). Protein S is a vitamin K-dependent protein which looses its anticoagulant properties when binding to C4BP. C4BP is composed of two types of subunits, the a-chain and the b-

Molecular Genetic Studies of the Blood Group ABO Locus in Man

The ABO blood group system is undoubtedly the most important genetic and phenotypic marker in clinical transfusion medicine. The A and B determinants are immunodominant, terminally located carbohydrate residues of glycoconjugates on erythrocytes and other cell surfaces. The enzymes responsible for assembly of these structures are glycosyltransferases encoded by the ABO genes on chromosome nine. T

Biosynthesis, Processing, and Sorting of Human Neutrophil Granule Proteins. Focus on Cathepsin G, Proteinase 3, and Azurocidin

The neutrophil granulocyte contains a number of multifunctional proteins stored in different subsets of granules. The azurophil granules, synthesized early during differentiation, harbour leukocyte elastase, cathepsin G, proteinase 3, and azurocidin; the members of the serprocidin family. In order to study the biosynthesis, processing, and intracellular sorting of the proteins, human cDNA encoding

MESENCHYMAL STEM- AND STROMAL CELLS IN BONE MARROW AND OSTEOSARCOMA

Primary mesenchymal stem cells (MSC) play a central role in bone marrow (BM) and during haematopoiesis. Yet, the exact phenotype and spatial distribution of primary MSC in the human BM are unknown. Their cultured progeny are promising candidates for clinical applications. MSC cultures however, are heterogeneous and, while critical for clinical applications, their exact composition is not known. W