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Introduction: Ischemic heart disease is the leading cause of death worldwide. The aims of this thesis were to evaluate different contemporary approaches in coronary care with regard to mortality and myocardial infarction. Methods: The thesis consists of 6 papers with 4 papers evaluating different exposures and their outcomes (clopidogrel pre-treatment, 5 different anti-platelet protocols, ticagrel

Infantile colic, involving an otherwise healthy infant crying and fussing more than three hours per day and more than three days per week, is a common problem in Western countries. Both the infant and the parents suffer during the months of persistent crying and there is a risk that the establishing of the early relationship might be disturbed. Safe and effective treatment that provides relief in

Utifrån psykodynamiska teorier om subjektivitet och postkoloniala teorier om rasifiering undersöktes i denna studie hur elever som inte ovillkorat räknades in i den föreställda svenska nationella gemenskapen gav mening åt erfaren-heter av rasifiering och hur de förstod sig själva i ett rasifierat landskap. Am-bitionen har varit att generera en situerad kunskap som bidrar till ökad med-vetenhet och

The aim of this thesis is to study how social workers experience and understand the laws they are regulated by, and if they perceive that the laws give them the right conditions to fulfil their purpose(s). Social Services have the important task of protecting society’s vulnerable groups, one of them being children, which entails huge power over other people’s lives, which is why social workers are

Significant collaborations with research partners in China are seen in many Western countries. With increasing geopolitical tensions governments, research institutions and individuals are increasingly called upon to address a proliferating array of risks and challenges associated with scientific collaboration with China. The situation is characterised by two parallel, intertwined processes. On the

The xanthophyll cycle is a mechanism for short term adaptation of plants to varying light intensities. It involves a reversible conversion of violaxanthin to zeaxanthin, via the intermediate antheraxanthin, upon high light intensities. This conversion is catalyzed by violaxanthin de-epoxidase (VDE) and the product after de-epoxidation, zeaxanthin, is involved in non-photochemical quenching of exce

Biological markers offer a way of assessing ethanol intake and determining whether a health problem is alcohol related. This study investigated the use of phosphatidylethanol (PEth) in blood as a new marker of alcohol abuse. PEth is an abnormal phospholipid, formed only in the presence of ethanol via the transphosphatidylation reaction of phospholipase D (PLD). A new HPLC-evaporative light scatter

Popular Abstract in Chinese 在世界許多地方蛾類幼蟲是主要的農業害蟲，但也有蛾類養殖業為獲取其絲綢蠶繭，例如家蠶。其實它也是第一個也是最好的研究揮發性有機分子用於傳遞信息的昆蟲研究模型。一般來說是雌蛾釋放信息素通過很長的距離來吸引雄性同類，而且具有出色的靈敏度和特異性。至今有記載的蛾類信息素都屬於同一類化合物(脂肪酸衍生物), 在信息素腺體內合成。信息素的生物合成涉及到脂肪酸的脫飽合，碳鏈縮短，並最終還原，乙酰化或氧化成醛等。這些反應過程中的酶已經進化到具有專一性，專門用於生產複雜的化學信號，使得蛾類的信息素存在豐富的化學多樣性。在本論文中，首先對幾個脫飽和酶進行研究。第一篇文章對冬尺蠖的脫飽合酶進行克隆並在酵母中通過異源表達證明了它具有把順十一,順十四,順十七-二十碳三烯酸轉化成順十一,順十四,順十七,十九-二十碳四烯酸的能力。這是有史以來第一個對甲基端脫飽合酶Moth caterpillars are major agricultural pests in many parts of the world. In general female moths attract male mates with their pheromone over long distance. Most of the described moth pheromones belong to the same class of chemical compounds, fatty acid derivatives that are produced de novo in the pheromone gland. The pheromone biosynthesis involves desaturation, chain-shortening by β-oxidation

Human endogenous retroviruses (HERVs) are remains of ancient retroviral infections of the germ line and constitute as much as 3 % of the human genome. HERVs are genetic elements that potentially may provide important biological functions by several different mechanisms. The ability to transpose long after the initial insertion into the germ line may provide a potent source of insertional mutagenes

Work-related musculoskeletal disorders are widespread, and are, for unclear reasons, more common among females than in males. Several risk factors have been described; constrained and awkward postures, repetitive and/or force demanding motions, and lack of recovery. The exposure to such risk factors was systematically assessed in 116 male and 206 female fish-processing industry workers. Large diff