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A high-confidence human plasma proteome reference set with estimated concentrations in PeptideAtlas

Human blood plasma can be obtained relatively noninvasively and contains proteins from most, if not all, tissues of the body. Therefore, an extensive, quantitative catalog of plasma proteins is an important starting point for the discovery of disease biomarkers. In 2005, we showed that different proteomics measurements using different sample preparation and analysis techniques identify significant

Alignment of Image Sensor using Piezoelectric Crystals

Förbättring av bildkvalité med hjälp av kristaller! Alla som någon gång har försökt att ta en bild vet den stora vikten av att ha bra fokus i bilden och hur störigt det är när man inte får till bra bildkvalité. Dagens kameror har blivit känsligare och det är idag viktigare än någonsin att alla komponenter i kameran finns på rätt plats. Bara några mikrometers skillnad på placeringen av bildsensornThe use of piezoelectric crystals as a way to achieve automatic alignment of an image sensor in a camera was investigated in collaboration with Axis Communications AB. Piezoelectric crystals can be created into different configurations, piezoelectric stacks being one of the simpler ones. By attaching three piezoelectric stacks behind an image sensor and applying voltage to the stacks, they expand

En särskilt utsatt situation – en rättsfallsstudie om det nya begreppet i våldtäktsparagrafen

The offence rape is a phenomenon in Swedish criminal law that engages many people and often creates vivid reactions when media reports about verdicts of acquittal in cases involving rape. The rape section has been changed at multiple times over the years. The last change entered into force July 1, 2013 when the new concept ”particularly vulnerable situation” (”särskilt utsatt situation”) replaced

Hållbarhetsredovisning - ett verktyg för förbättrat hållbarhetsarbete?

Sustainability reporting has emerged as a common practice of 21st-century business. A sustainability report is a report published by an organization that presents the economic, environmental and social impacts caused by its activities. The Global Reporting Initiative (GRI) is a non-profit organization with the mission to promote the transition to a sustainable global economy by providing a framewo

Hur aktsam kan en sexköpare förväntas vara? - Om innebörden av aktsamhetskravet i 6 kap. 13 § BrB när sexköp av barn i 6 kap. 9 § BrB bedöms och dess förenlighet med effektivitets- och rättssäkerhetshänsyn

Från och med den 1 januari 2020 skärptes straffskalan för sexköp av barn. Syftet med åtgärden var att förstärka det straffrättsliga skyddet för ungdomar mot att dras in i prostitution. Brottet är förknippat med låg åtalsfrekvens. Det har tidigare förklarats med att aktsamhetskravet i förhållande till ålder i 6 kap. 13 § BrB - som täcker flera sexualbrott med åldersgräns - var särskilt svårt att upIn January 2020 the range of punishment for exploitation of a child through the purchase of a sexual act got stricter. The reasoning behind the change was to strengthen the criminal justice protection for these children. Exploitation of a child through the purchase of a sexual act is associated with a low prosecution frequency. An explanation for this has been that the rule of negligence in the si

”För jag är inget hot mot dem” - en kvalitativ studie om boendestödjare, deras arbetsfält och kompetens

Due to the lack of a commonly required education amongst street-level bureaucrats in supported housing, the focus of this study was to analyse how the street-level bureaucrats in supported housing experienced their work and education. We were also interested in how they felt their knowledge and skills were utilized in their organizations. In the last decade, the number of supported housing efforts

Fällande dom till varje pris? En analys av penningtvättsbrottet och dispositionsförbudet ur ett rättssäkerhets- och effektivitetsperspektiv

Penningtvätt utgör ett problem för samhällsekonomin, då det innebär ett hot mot det finansiella systemet om pengar med kriminellt ursprung hamnar i den legala ekonomin. Sveriges skydd för att kriminella tillgångar tvättas i den legala ekonomin har visat sig ineffektivt. Financial Action Task Force on money laundering har påpekat bristerna i svensk rätt och rekommenderat åtgärder då det inte finns If money with illicit origins enters into circulation in the financial system it poses a threat to the mechanisms of the financial system. Financial Action Task Force have concluded that the Swedish legal requirements for combating money laundering is insufficient, and the organisation have advised Swedish authorities to effectuate preventive measures. Therefore, the Swedish legal system is not co

Omedveten oaktsamhet i mål om oaktsam våldtäkt

In 2018, Sweden passed a new law regarding rape, which is based on the lack of voluntary participation or in other words, consent. This means that it is now the perpetrators intent, regarding that the other person does not participate voluntarily in the sexual act, which lays in the court judgements focus. Another change was that a new offense where passed, negligent rape. Thus, criminal liability

Competition between managed honeybees and wild bumblebees - Quantifying dietary overlap in semi-natural grasslands

Under de senaste årtiondena har bin, såsom humlor, minskat i både antal arter och populationsmängder. Detta är ett stort problem för vårt samhälle då både jordbruket och naturliga ekosystem till stor del är beroende av dessa pollinatörer. Det är speciellt problematiskt att humlor minskar då de har förmågan att utföra en speciell sorts pollinering (buzz-pollination) som några av våra vanligaste gröThe decline of bees, such as bumblebees, over the last decades raises concerns as they are key pollinators in both agricultural and natural ecosystems. One proposed cause for the decline of wild bees is competition for food resources with managed honeybees. Detrimental effects of competition can result where co-existing species exhibit a high degree of shared resource use (i.e., niche overlap). Th

Vibration analysis for condition monitoring of mechanical presses

Ger pressar dig bra vibrationer? Idag är allt från kaffemaskiner och gräsklippare till krutpistoler och bilar uppkopplade och kan närsom-helst ge oss en statusrapport genom bara ett par klick i en app. Vi kan med mobilen kolla bilens bräns-lenivå, geografiska position eller om vi glömt att låsa på väg in från par-keringen. Så varför skulle inte statu-sen på utrustningen som används för att tillveIn a world where the concept of just-in-time has been lifted outside of the manu-facturing world and onto the market, the increasing demand of luxury wares like cars is accompanied only by tougher industrial conditions and no room for error. Loss of productivity and decrease in efficiency can be devastating to any manufac-turing company in today’s market climate. One of the largest causes of these

Artikel 6 skatteflyktsdirektivet - Generalklausulen mot missbruk

The Anti-Tax Avoidance Directive (ATAD) was adopted on 12 july and needed to be implemented by the member states on 31 december 2018. The general anti-avoidance rule (GAAR) in article 6 is the interest of this thesis. The purpose with the GAAR is to access the arrangements or transactions that try to circumvent the tax legislation. The GAAR should cover gaps and apply to arrangements that are not

Ramsvikslandets Naturreservat; en utvärdering av skötseln, kopplat till hotade gentianaväxter

Liten blomma i backen, formad av bondens blod, svett och tårar En bit innan semesterparadiset Smögen, ligger en liten ö med mångårig historia. Här har marken odlats under många hundra år. På sommaren slåttrade man gräset, bar det till höbalar, och korna betade lojt på med utsikt över klipporna och havet. Störningarna var stora på gräsmarkerna, lien skar av växterna och korna betade, för många växWith the gain of productivity in farming the last decades, there has been great loss in species richness. Many plant species that have evolved and adapted alongside to traditional farming and benefiting to the managed land use, are now disappearing in great numbers. Three thirds of Sweden’s endangered plant species are those who thrive in managed grasslands like meadows and grazing areas. The trad

Sublime Transactions. The Gestures of Poetry and Criticism with Anne Carson, the Scholar-Poet

The 20th century, as well as the 21st, is ripe with hermeneutic anxiety concerning the survival of the object of interpretation and the right way to study literature. In this thesis, the Canadian scholar-poet Anne Carson is studied as a framework to an understanding of how poetry and literary criticism – the event of hermeneutics – co-occur, converge, and diverge. Specifically, it studies Carson’s

Down to the Minimum: An analysis of the family reunification rights under the Temporary Law

In July 2016, the Law on temporary limitations to the possibility of being granted residence permit in Sweden (the Temporary Law) came into force. The Temporary Law implied a sharp turn in Swedish asylum legislation. The right to family reunification, which previously had been granted subsidiary protection beneficiaries and refugees on a similar basis, was suddenly heavily restricted for beneficia

Ecosystem response to weather extremes and impact on atmospheric composition - A case study of the 2018 summer heatwave

Extremväder, såsom torkan 2018, förväntas öka i framtiden på grund av den pågående globala uppvärmningen. Detta kommer bland annat påverka världens skogar, vilka är viktiga i klimatsystemet, framför allt på grund av deras förmåga att binda koldioxid, men även deras utsläpp av biogena volatila organiska kolväten. Skogarnas förutsättningar att bidra till klimatsystemet på detta sätt kan dock ändras Extreme weather events, such as heatwaves and droughts, are predicted to increase due to global warming, significantly impacting forest ecosystems. These ecosystems play a crucial role in the climate system through carbon sequestration and the emission of Biogenic Volatile Organic Compounds (BVOCs), which can form Secondary Organic Aerosols (SOAs) and thus have a cooling effect on the climate. In

Solid Waste Management and Waste-to-Energy Feasibility in Kigali - A Case Study of the Mpazi Rehousing Project

I takt med att världens befolkning växer ökar även mängden genererat hushållsavfall, vilket utgör en betydande påverkan på miljö och samhälle. Under 2018 genererades cirka 2 miljarder ton avfall globalt, en siffra som förväntas stiga till 3,4 miljarder ton till 2050. En stad som på senare år har gjort stora framsteg inom avfallshantering är Rwandas huvudstad Kigali, känd som Afrikas renaste stad. This master’s thesis explores a Waste-to-Energy solution for Kigali, specifically focusing on the Mpazi Rehousing Project. Kigali faces challenges with Solid Waste Management (SWM) despite its reputation for cleanliness and efficient urban planning. It aims to transform biowaste into biogas, contributing to sustainable urban development and reducing waste at Nduba landfill. The research addresses

När hållbarhet blir till lag – Hur implementeringen av CSDDD utmanar vinstsyftet och utvecklingen av hållbart företagande

When the European Commission’s Corporate Sustainability Due Diligence Directive (CSDDD) was voted through in July 2024, the playing field for companies operating within the European Union (EU) changed. The CSDDD transforms the previously voluntary responsibility to adhere to Corporate Social Responsibility (CSR) into legally binding regulations. Companies subject to the CSDDD are required to perfo

Mellan nationell och europeisk åklagare – En analys av svenska åklagares handlingsskyldigheter vid oupplösligt sammankopplad brottslighet

Sweden became an official member of the European Public Prosecutor’s Office (the ‘EPPO’) in July of 2024. Joining the EPPO represents a major change for Swedish procedural criminal proceedings, as the judicial system needs to adapt to the fact that an EU body now has direct authority to take actions related to crimes within Sweden’s jurisdiction. This change is particularly apparent in relation to

Recent advances in neuroimaging of Alzheimer's disease and related dementias

This review covers recent advances (2023–2024) in neuroimaging research into the pathophysiology, progression, and treatment of Alzheimer's disease (AD) and related dementias (ADRD). Despite the rapid emergence of blood-based biomarkers, neuroimaging continues to be a vital area of research in ADRD. Here, we discuss neuroimaging as a powerful tool to topographically visualize and quantify amyloid,