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Background:Transcriptomic profiles have shown promise as predictors of response to neoadjuvant chemotherapy in breast cancer (BC). This study aimed to explore their predictive value in the advanced BC (ABC) setting.Methods:In a Phase 3 trial of first-line chemotherapy in ABC, a fine needle aspiration biopsy (FNAB) was obtained at baseline. Intrinsic molecular subtypes and gene modules related to i
Polycyclic aromatic hydrocarbons (PAHs) have endocrine disrupting properties and they cross the placental barrier, but studies on gestational exposure and child anthropometry are inconclusive. We aimed to elucidate the impact of early gestational PAH exposure on anthropometry from birth to 10 years of age in 1295 mother-child pairs from a nested sub-cohort of the MINIMat trial in Bangladesh. Sever
Purpose Asthma is frequently reported in endurance athletes. The aim of the present study was to assess the long-term airway inflammatory response to endurance exercise in high-level athletes with and without asthma. Methods In a cross-sectional design, 20 asthmatic athletes (10 swimmers and 10 cross-country skiers), 19 athletes without asthma (10 swimmers and 9 cross-country skiers), and 24 healt
Chronic Obstructive Pulmonary Disease (COPD) is often caused by smoking and other stressors. This causes oxidative stress, which induces numerous changes on both the transcriptome and proteome of the cell. We aimed to examine if the endomembrane pathway, including the endoplasmic reticulum (ER), Golgi, and lysosomes, was disrupted in fibroblasts from COPD patients as opposed to healthy ever-smoker
Retinal implant devices are becoming an increasingly realizable way to improve the vision of patients blinded by photoreceptor degeneration. As an electrode material that can improve restored visual acuity, carbon nanotubes (CNTs) excel due to their nanoscale topography, flexibility, surface chemistry, and double-layer capacitance. If vertically aligned carbon nanotubes (VACNTs) are biocompatible
Patients with systemic lupus erythematosus (SLE) face an approximately 30 % risk of thrombosis post-diagnosis. However, there remains significant knowledge gaps regarding causative mechanisms, and there is a lack of specific antithrombotic guidelines. This systematic review aims to examine the existing literature regarding the mechanisms contributing to thrombosis risk in SLE, focusing on five pre
LTHs Julkalender 2021 Varje dag öppnas en lucka i julkalendern , från den 1 december och fram till julafton. Under varje lucka finns ett videoklipp med ett experiment. Du kan alltid titta tillbaka på ett experiment! Börja med Lucka 0 redan idag! Bakgrund Sedan 2007 har LTH-teknologer via 24 kortfilmer experimenterat fram en julkalender som på ett pedagogiskt och lättsamt sätt ger inblick i teknisk
https://www.lth.se/fileadmin/julkalender/julkalender/2021/info.php - 2026-06-16
Title: Barriers to Sustainable Investing Seminar date: 2021-06-02 Course: FEKH29, Bachelor Degree Project in Marketing Undergraduate Level, 15 ECTS Authors: Julia Benke, Filippa Kjellberg, Ida Svensson Advisor: Peter Svensson Key words: Barriers, Gaps, Sustainability, Intention, Attitude, Behavior Research question: Which barriers obstruct sustainable investing? Purpose: The study aims to contrib
I 29 kap. 1 § brottsbalken anges att straffet för ett brott ska bestämmas inom ramen för den tillämpliga straffskalan efter brottets straffvärde. Straffvärdet för ett brott kan anses spegla brottets allvarlighet och flera omständigheter kan påverka straffvärdet. I 29 kap. 2 § BrB anges försvårande omständigheter som påverkar straffvärdet i skärpande riktning. Hedersmotiv kan beaktas inom ramen fChapter 29 section 1 of The Swedish Criminal Code, hereafter called SCC, states that the penalty shall be determined within the framework of the applicable scale of penalties according to the penalty value of the offence. The penalty value can be considered a reflection of the seriousness of the offence. There are a number of circumstances which may affect the penalty value. Chapter 29 section 2 S
The Swedish Government wants to fight honor-related crime and believes that the introduction of a special honor crime is a way to further highlight that such violence is unacceptable. Therefore, in July 2019, the Government commissioned a special investigator to analyze and take a position on a special criminal provision that explicitly aims at honor-realtered violence and oppression. The inquiry
Following the activation of the International Criminal Court’s jurisdiction over the crime of aggression in July 2018, these acts are for the first time since the Nuremberg Tribunal possible to prosecute before an international court. The crime of aggression may only be conducted by persons in a position effectively to exercise control over or direct the political or military action of a State. Th
Aron Flam was charged on July 17th, 2020 with copyright infringement. He used an already existing work "En svensk tiger" by Bertil Almqvist and made a parody out of the work that he then used for the cover of his book “Det här är en svensk tiger”. Flam uses his freedom of speech in his book which discusses “silence culture” in Sweden, from a critical perspective. He uses the parody to co
Den svenska offentliga sektorn har under de senaste decennierna varit föremål för en rad förändringar vars konsekvenser satt sina spår i många av dess verksamheter. Förändringsprocessens startskott skedde redan på 1980-talet och den offentliga sektorn präglas sedan dessa allt mer av ökad privatisering, konkurrensutsättning, (de)centralisering och ökade krav på effektivisering. Samtliga ovanstående
Svenskt ställföreträdarskap för vuxna består av möjligheten att utse en god man eller förvaltare. Tidigare fanns en möjlighet att upprätta en fullmakt för någon som kunde hjälpa den enskilda även efter att denna p.g.a. ålder eller annan orsak inte längre var beslutsförmögen. Det förfarandet kritiserades på många håll, inte minst genom NJA 2015 s. 851. Av denna anledning pågår arbetet för att anta Swedish deputisation for adults comprises the possibility to designate an administrator or trustee. Earlier, there were a possibility to nominate a proxy agent to assist individuals with their affairs even after a they due to old age or any other reason not were able to. This procedure has become questioned, not least in the Swedish Supreme Court, NJA 2015 s. 851. Due to this reason, the Swedish g
Staden Frutal, centrerad i den brasilianska delstaten Minas Gerais är idag under stark urbanisering och utveckling. Målet med denna studie var att ta reda på om den starka urbaniseringen har påverkat närliggande vattensystem och dess vattenkvalité. I studien har vattenkvalitén i floden Frutal, en flod liggandes centralt i staden Frutal, jämförts med vattenkvalitén i floden Bebedouro, en lantlig flThis study highlights the key issues that urban river systems face due to urbanization. The city of Frutal (20°01' 32.17”S 48°56' 09.62” W) centered in the Brazilian state of Minas Gerais is under urban expansion today. The aim of this study was to compare two rivers in this area, the Frutal River, an urban located river, with the Bebedouro River, which is a rural river approximately 3 km
In July 2014 new law provisions were introduced to strengthen the protection against child marriage in Sweden and as a result the possibility to grant persons under the age of 18 permission to marry was abolished. The provisions regarding recognition of foreign marriages were also further limited in cases where at least one of the parties had ties to Sweden and was under the age of 18 at the time
Antalet medborgare inom Europeiska unionen som nyttjar den fria rörligheten ökar konstant. Fler och fler familjer har på något sätt en internationell koppling, ett vanligt exempel är äktenskap mellan två personer med olika medborgarskap. När vardagslivet blivit mer globaliserat och oberoende av nationsgränser blir det ibland problematiskt då lagstiftningen inte anpassats därefter. För bara ett par
On July 1st, 2018, a reform regarding the Swedish sexual offence legislation came into force, which meant that the crime of rape in Chap. 6 § 1 of the Penal Code was constructed around the concept of voluntariness instead of around the concept of coercion. The new offence negligent rape was also introduced in Chap 6. § 1 a of the Penal Code. The paragraph regarding rape is still based on previous
