Sökresultat

Filtyp

Din sökning på "*" gav 529788 sökträffar

S-100beta stimulates neurite outgrowth in the rat sciatic nerve grafted with acellular muscle transplants

S-100beta promotes neurite extension in vitro and motoneuron survival in the chicken embryo. We demonstrate here that local administration of S-100beta stimulates the sciatic nerve regeneration into acellular muscle grafts. Normally there is a 8-10 day delay in the regeneration of axons into such grafts. Local administration of S-100beta (0.5-1.0 microg/h) significantly stimulated regeneration int

Therapeutic choices for patients with hemophilia and high-titer inhibitors

Effective treatment of bleeding episodes in hemophilia with high titer inhibitors (HTI) remains a challenge, despite the fact that the therapeutic armamentarium has expanded considerably over the past few years. Treatment safety has improved with the availability of porcine factor VIII (FVIII) and bypassing products such as recombinant factor VIIa (rFVIIa), and plasma-derived activated Prothrombin

Detection of vitamin K-dependent proteins in venoms with a monoclonal antibody specific for gamma-carboxyglutamic acid.

gamma-Carboxyglutamic acid (Gla) is an unusual amino acid that is synthesized post-translationally from glutamate in a vitamin K-dependent reaction. The dicarboxylic side chain of Gla chelates Ca(2+), a property important for the biological activity of vitamin K-dependent proteins. To date, Gla-containing polypeptides have been identified in venom from two groups of organisms: elapid snakes, and s

Modelling of pulverised wood combustion: a comparison of different models

Several models have been proposed in the literature for numerical simulations of pulverised wood drying, pyrolysis, gasification and combustion processes. These models are based on different assumptions and they yield fairly different results. In the present study a pulverised wood flame in a laboratory vertical furnace is chosen as the test case to evaluate the different sub-models including, dry

Effect of the antibacterial activity of pig pancreatic juice on human multiresistant bacteria.

Introduction: The role of the exocrine pancreas in regulating gut microflora colonization is unclear. The main objective in the current study was to assess the effect of pancreatic fluid on the growth of pathogenic bacteria and fungi. Methods: The antibacterial activity of pure pig pancreatic juice collected from catheterized, healthy, conscious, and anesthetized pigs was investigated with multir

Scolecodonts from the Upper Danian (Paleocene) of Skane, Sweden

Jaws of fossil marine polychaete annelids, scolecodonts, from Sweden have chiefly been reported from Silurian strata. The specimens described in this paper come from Upper Danian (Paleocene) strata of the Limhamn quarry in Skane (Scania), the southernmost province of Sweden. The jaws are assigned to the Recent genera Glycera and Drilonereis, but their state of preservation did not allow species id

Bose-Einstein condensates with attractive interactions on a ring

Considering an effectively attractive quasi-one-dimensional Bose-Einstein condensate of atoms confined in a toroidal trap, we find that the system undergoes a phase transition from a uniform to a localized state, as the magnitude of the coupling constant increases. Both the mean-field approximation, as well as a diagonalization scheme, are used to attack the problem.

Aggregate manganese Schiff base moieties by terephthalate or acetate: Dinuclear manganese and trinuclear mixed metal Mn-2/Na complexes

A reaction system consisting of terephthalic acid, NaOH, inorganic Mn(II) or Mn(III) salt, and salicylidene alkylimine resulted in dinuclear manganese complexes (salpn)(2)Mn-2(mu-phth)(CH3OH)(2) (1, salpn = N,N'-1,3-propylene-bis(salicylideneiminato); phth = terephthalate dianion), (salen)(2)Mn-2(mu-phth)(CH3OH)(2) (2, salen = N,N'-ethylene-bis(salicylideneiminato)), (salen)(2)Mn-2(mu-phth)(CH3OH)

Mechanism of Cryopolymerization: Diffusion-Controlled Polymerization in a Nonfrozen Microphase. An NMR Study

Polymerization of dimethylacrylamide (DMAAm) cross-linked with PEG diacrylate was studied using H-1 NMR both in situ in a semi frozen system and in a supercooled aqueous system. The amount of nonfrozen microphase, in which polymerization proceeds, is defined by the concentration of the starting monomers and the freezing temperature, which depends on the depression in freezing temperature caused by

Specific cysteine protease inhibitors act as deterrents of western flower thrips, Frankliniella occidentalis (Pergande), in transgenic potato

In this study, the effects of the accumulation of cysteine protease inhibitors on the food preferences of adult female western flower thrips, Frankliniella occidentalis (Pergande), were investigated. Representative members of the cystatin and thyropin gene families (stefin A, cystatin C, kininogen domain 3 and equistatin) were expressed in potato (Solanum tuberosum) cv. Impala, Kondor and Line V p

A qualitative methodology for tailoring SPE activities in embedded platform development

For real time embedded systems software performance is one of the most important quality attributes. Controlling and predicting the software performance in software is associated with a number of challenges. One of the challenges is to tailor the established and rather general performance activities to the needs and available opportunities of a specific organization. This study presents a qualitat

Sex differences in risk factors for suicide after attempted suicide - A follow-up study of 1052 suicide attempters

Aim This study aims to investigate suicide risk factors after attempted suicide and whether and how these risk factors differ between the sexes. Method A total of 1052 suicide attempters admitted to the Medical Emergency Inpatient Unit, Lund University Hospital, Sweden were followed up concerning suicide and death from other causes after a median period of 6 years and 5 months. in all, 50 persons

Analysis of surface electrocardiograms in atrial fibrillation: techniques, research, and clinical applications

Atrial. fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Neither the natural history of AF nor its response to therapy is sufficiently predictable by clinical and echocardiographic parameters. The purpose of this article is to describe technical aspects of novel electrocardiogram (ECG) analysis techniques and to present research and clinical applications of these m

23S rRNA assisted folding of cytoplasmic malate dehydrogenase is distinctly different from its self-folding

The role of the 50S particle of Escherichia coli ribosome and its 23S rRNA in the refolding and subunit association of dimeric porcine heart cytoplasmic malate dehydrogenase (s-MDH) has been investigated. The self-reconstitution of s-MDH is governed by two parallel pathways representing the folding of the inactive monomeric and the dimeric intermediates. However, in the presence of these folding m

Primate models for human immunodeficiency virus infection. Evolution of receptor use during pathogenesis.

Animal models greatly facilitate understanding of transmission, pathogenesis and immune responses in HIV and SIV infection and provide models for studies on the effect of candidate drugs or vaccines. However, there are several aspects that one should consider when drawing conclusions from results obtained from animal models. First, the genetic relationship of primate lentiviruses cannot be disrega