Lung transplantation is limited by a scarcity of suitable donors resulting in high waiting list mortality. Ex vivo lung perfusion (EVLP) allows the evaluation and reconditioning of marginal donor lungs for use in transplantation. This study aimed to compare clinical outcome of patients transplanted with marginal organs by means of EVLP with a standard lung transplant cohort through a multicenter o

The increasing demand for pulmonary retransplantation (re-LTx) raises ethical issues on the correct allocation of the scarce donor pool. Thus, we performed a thorough review of the current results for re-LTx in the Nordic countries.

Gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) regulate the reproductive axis. Their analogs have been found to influence gastrointestinal activity and enteric neuronal survival. The aims of the study were to investigate expression and cellular distribution of GnRH, LH, and FSH and their receptors in human and rat gastrointestinal tract.

According to Polarity Theory, human worldviews are structured by a polarity between Humanism, which glorifies humanity, portraying human beings and their experiences as intrinsically valuable, and Normativism, which portrays human beings as able to realize themselves and attain value only in relation to external norms and ideals. Previous research has suggested that humanism and normativism are, c

The literature on transnational civil society tends to treat civil society organizations CSOs) as independent actors, accomplishing policy change largely through moral force or popular pressure. However, a significant portion of CSO successes in policy advocacy actually utilizes alliances with state actors. To understand the implications of this ‘state channel’ of CSO influence, we develop a new m

This study explores the concept of pasture, looking at how people classify it and the features that determine how an image is classified. The analysis is based on two parallel studies that used the same image material. The first study was a web-based survey in which respondents were asked to make a pairwise comparison of the images they felt best corresponded to pasture. The second study used eye-

We report four previously undescribed families with germline BRCA1-associated protein-1 gene (BAP1) mutations and expand the clinical phenotype of this tumor syndrome. The tumor spectrum in these families is predominantly uveal malignant melanoma (UMM), cutaneous malignant melanoma (CMM) and mesothelioma, as previously reported for germline BAP1 mutations. However, mutation carriers from three new

The influence of surface micro topography of CVD α-Al2O3 coatings, deposited on cemented carbide inserts, on tribological characteristics in sliding contact and in metal cutting has been investigated using quenched and tempered steel as counter/work material. Pin-on-disc and turning tests were carried out and post-test characterization using 3D optical surface profilometry and scanning electron mi

The impact of climate and emissions changes on the deposition of reactive nitrogen (Nr) over Europe was studied using four offline regional chemistry transport models (CTMs) driven by the same global projection of future climate over the period 2000-2050. Anthropogenic emissions for the years 2005 and 2050 were used for simulations of both present and future periods in order to isolate the impact

Reefs developed simultaneously during the latest Sandbian/earliest Katian global Guttenberg Isotopic Carbon Excursion (GICE) in several places across Baltoscandia. Latest Sandbian/earliest Katian patch reefs are also described from the Vasalemma Formation of northern Estonia. The Saku Member of the Vasalemma Formation was previously considered as a proximal facies related to the reefs. However, th

This article analyses household-based food transfers as an expression of multi-local livelihoods. Transfers of maize outside the co-resident household unit are analysed on the basis of data from 2857 smallholder households across nine African countries. The study complements a growing interest in the role of food transfers for urban food security, through considering the food security implications

Developmental theorists have proposed for a long time that the prevailing focus on stable individual differences has obstructed the discovery of short-term covariations between cognitive performance and contextual influences within individuals that may help to uncover mechanisms underlying long-term change. As an initial step to overcome this imbalance, we observed measures of motivation and worki

The aim of the present study was to test the hypothesis that a prolonged refeeding duration after successful very-low-energy diet (VLED)-induced weight loss beneficially affects weight development and eating behaviour. Patients (it 269) were recruited to a I-year obesity treatment programme with 12 weeks of an initial VLED. After the VLED, patients with 10 % weight loss were randomly allocated to

It is known that many-fermion systems, such as complex atoms and nuclei, reveal (at some level of excitation energy) local signatures of quantum chaos similar to the predictions of random matrix theory. Here, we study the gradual development of such signatures in a model system of up to 16 fermions interacting through short-range pairing-type forces in a two-dimensional harmonic trap. We proceed f

The eusocial Acacia gall-inducing thrips Kladothrips intermedius (Thysanoptera: Phlaeothripinae) secretes defensive anal droplets when threatened. In addition to harmful substances, droplets of other thysanopteran species are known to contain semiochemicals such as alarm pheromones and/or repellents against enemies. Both Kl. intermedius larval stages and adult castes (soldiers and dispersers) prod

The far-infrared absorption spectra have been recorded for hydrogen-bonded complexes of water with ethanol embedded in cryogenic neon matrices at 2.8 K. The partial isotopic H/D-substitution of the ethanol subunit enabled by a dual inlet deposition procedure enables the observation and unambiguous assignment of the intermolecular high-frequency out-of-plane and the low-frequency in-plane donor OH

Acute otitis media (AOM) is the most common bacterial infection in children and has a very varied clinical spectrum, ranging from spontaneous resolutions to serious complications. The effect of antibiotics in AOM depends on the chosen outcome, but has been shown to reduce pain somewhat, and have a greater beneficial effect in severe cases of AOM. Today, not all episodes of AOM are treated with ant

Background: Irreversible electroporation (IRE) is a local tumor treatment. Thin needles are placed percutaneously around the tumor under ultrasound guidance. Short pulses of direct current sent through the tissue irreversibly increase cell membrane permeability leading to cell death. We report a phase I study assessing the safety of ultrasound guided percutaneous IRE in patients with localized pan

Prior findings indicate that individuals scoring high on vital exhaustion show a dysfunctional stress response (DSR), that is, reduced cortisol reactivity and habituation to psychosocial stressors. The main aim of the present study was to examine whether a DSR may be a vulnerability factor in exhaustion disorder (ED). We examined whether a DSR is present during the early stages of ED, and still is