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Objective: To investigate cellular immune responses to the herpes zoster (HZ) subunit (HZ/su) vaccine in patients with rheumatoid arthritis (RA) treated with Janus kinase inhibitors (JAKis). Methods: RA patients treated with JAKi (n=46) at the Department of Rheumatology, Skåne University Hospital, Sweden, and healthy controls (n=37) received two doses of the HZ/su vaccine. Blood samples were colle

Background/Objectives: Mitochondrial dysfunction is a major cause of brain injury in patients with primary mitochondrial disease. New mitochondrial therapeutics and non-invasive tools for efficacy monitoring are urgently needed. To these ends, succinate prodrug NV354 (methyl 3-[(2-acetylaminoethylthio)carbonyl]propionate) and diffuse optical techniques are promising. In this proof-of-concept study

Aim: To provide an overview of a project aimed at enhancing person-centred surgical care through teamwork and professional development. Design: A discursive paper with the purpose of describing and discussing the project activities to strengthen person-centred care, teamwork and professional development. Methods: This project aimed to strengthen evidence-based surgical nursing care within a Surger

Can the way a word is used give legitimacy to a political movement? Feminism, Violence, and Representation in Modern Italy traces the use of the word "femminicidio" (or "femicide") as a tool to mobilize Italian feminists, particularly the Union of Women in Italy (UDI). Based on nearly two years of fieldwork among feminist activists, Giovanna Parmigiani takes a broad look at the many ways in which

Treatment response in pediatric social anxiety disorder (SAD) is highly variable, and symptoms may be maintained by maladaptive attention. A previous study found that youth with SAD scan a more restricted area of faces than healthy controls during emotion recognition, potentially limiting interpretation of social cues. The current study followed up on these results by examining whether restricted

Wages earned by men are often used as an indicator of the material standard of living (MSoL). However, this indicator relies on several assumptions when used for comparisons across time and space. Considering these assumptions will improve estimates of the MSoL from wages. One necessary assumption is that households in the compared populations relied on the primary income of the male head of house

Based on an ethnographic research among contemporary Pagan communities in Southern Italy (Salento, Apulia), The Spider Dance challenges ideas of historicity, healing, place-making and the experience of time among persons engaged in reviving, continuing, or re-creating traditional Pagan practices. The Spider Dance looks at a specific Pagan group, the sisters of the cerchio (circle), and their ritua

Context. Neutron-capture elements are believed to make up almost all elements heavier than iron in the periodic table. By studying the abundance of these elements throughout the Galaxy, it is possible to put constraints on how and where neutron-capture processes occur. Determining elemental abundances is made possible through the correct interpretation and modelling of astrophysical spectra. Key i

To facilitate a simultaneous treatment of an arbitrary number of colors in representation theory-based descriptions of QCD color structure, we derive an N-independent reduction of SU(N) tensor products. To this end, we label each irreducible representation by a pair of Young diagrams, with parts acting on quarks and antiquarks. By combining this with a column-wise multiplication of Young diagrams,

Aims: Drug–gene interactions (DGIs) modify drug response and safety, yet their influence on diabetic microvascular complications remains unclear. This study aimed to elucidate the role of DGIs in these complications. Materials and Methods: Using UK Biobank (UKB) data, we identified medications frequently prescribed to individuals with diabetes and defined DGIs based on the Food and Drug Administra

Ur skriften: "Från juni 2022 till december 2025 visades utställningen ”Lunds universitet – historia och historier” på Historiska museet vid Lunds universitet. Utställningen producerades i samarbete med Lunds universitetshistoriska sällskap. Denna skrift återger merparten av innehållet i utställningen. Vissa texter har uppdaterats utifrån senare händelser och upptäckter."

According to Ethan Mollick, artificial intelligence (AI) is the most recent general purpose technology (GPT), the “once-in-a-generation technologies, like steam power or the internet, that touch every industry and every aspect of life” (2024, p. xv). Unlike the slowly unfolding transformations caused by these earlier GPTs, the changes sparked by AI seem to evolve daily. This rapid pace creates a s

BackgroundChronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) are characterized by persistent airway inflammation and airflow limitation. Measuring airway inflammation may be of value both in research and clinical practice. Calprotectin, a protein associated with neutrophil activation, serves as a potential biomarker for airway inflammation. This study evaluates the performance o

Hypothalamic inflammation underlies diet-induced obesity and diabetes in rodent models. While diet normalization largely allows for recovery from metabolic impairment, it remains unknown whether long-term hypothalamic inflammation induced by obesogenic diets is a reversible process. In this study, we aimed at determining sex specificity of hypothalamic neuroinflammation and gliosis in mice fed a f