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Background: Involvement of B cells in the pathogenesis of rheumatoid arthritis (RA) is supported by the presence of disease-specific autoantibodies and the efficacy of treatment directed against B cells. B cells that express low levels of or lack the B cell receptor (BCR) co-receptor CD21, CD21−/low B cells, have been linked to autoimmune diseases, including RA. In this study, we characterized the

G protein-coupled receptor 30 (GPR30), also named G protein-coupled estrogen receptor (GPER), and the β1-adrenergic receptor (β1AR) are G protein-coupled receptors (GPCR) that are implicated in breast cancer progression. Both receptors contain PSD-95/Discs-large/ZO-1 homology (PDZ) motifs in their C-terminal tails through which they interact in the plasma membrane with membrane-associated guanylat

A fundamental issue in the metabolic field is whether it is possible to understand underlying mechanisms that characterize individual variation. Whole-animal performance relies on mitochondrial function as it produces energy for cellular processes. However, our lack of longitudinal measures to evaluate how mitochondrial function can change within and among individuals and with environmental contex

Current literature show that frequency diverse arrays (FDAs) are able of producing range–angle-dependent and time-variant transmit beampatterns, but the resulting time and range dependencies and their characteristics are still not well understood. This paper examines the FDA transmission model with an emphasis on analyzing the beam auto-scanning characteristics and the equivalence with the MIMO be

Publicerad på bloggen "Frontiers of Socio-Legal Studies"Published at the blog "Frontiers of Socio-Legal Studies"

Previous research showed that living closer to bus stops could be a factor in promoting a healthy and active lifestyle. However, most of the studies relied on self-reported measures of distance, which might be affected by several confounders. In this study, self-reported distances among study participants were compared to actual ones, computed by the use of GIS (Geographic Information System) tech

The Islamic Republic of Iran (IRI) has two main intelligence organizations: the Ministry of Intelligence (MOI) and the Intelligence Organization of the Islamic Revolutionary Guard Corps. The two organizations are highly active on foreign soil with malign activities like assassinations. In 2018, the third secretary of the IRI embassy in Austria, Assadollah Assadi, was arrested and later convicted o

Recent work in cognitive science argues for the illusory nature of conscious will and considers occasional “blindness” to manipulations as indicative of our lack of awareness in choice making (e.g., Dennett, 1996; Johansson et al., 2013; Wegner, 2018). This claim is based upon the tendency of experimental participants not to detect such manipulations, and the similarity between verbal justificatio

This study aims to establish a methodological framework for investigating deception in both spoken and written language production. A foundational premise is that the production of deceitful narratives induces heightened cognitive load that has a discernable influence on linguistic processes during real-time language production. The study includes meticulous analysis of spoken and written data fro

Kvinder fylder kun 5,2% af alle navngivne personer i danske læremidler til faget historie.

Cardiometabolic conditions such as obesity and type 2 diabetes (T2D) are among the first causes of death globally, and the number of people affected is rapidly increasing. Both conditions are intricately connected and are associated with many life-threatening cardiovascular disease (CVD). However, both obesity and T2D are highly heterogeneous, such that not all individuals with these conditions de

Interview with artistic director Bettina Wackernagel in the framework of the 10th anniversary of the festival Heroines of Sound Festival Berlin about women in electronic music today and in the past

Policies for shifting household electricity load are in focus in several countries, aimed at optimizing grid operation and tackling current and expected challenges from consumption patterns, like increased peak loads on the grid. Central here are recent developments in capacity charges, where the use of significant amounts of grid capacity is priced high, compared to the traditional pricing of ele

Objective In numerous studies aspiring to clarify when to discontinue direct oral anticoagulants (DOAC) before central nerve blocks (CNB), information about the technique: spinal, epidural, indwelling catheter, multiple attempts, ‘bloody tap’: is incomplete. This creates difficulty making evidence-based recommendations regarding the safest time frame between the last dose of DOAC and CNB to avoid