Multigene expression signatures provide a molecular subdivision of early breast cancer associated with patient outcome. A gap remains in the validation of such signatures in clinical treatment groups of patients within population-based cohorts of unselected primary breast cancer representing contemporary disease stages and current treatments. A cohort of 3520 resectable breast cancers with RNA seq

We report on the structural properties of ionic microgel particles subjected to alternating electric fields, using small-angle neutron scattering. The experiments were performed under so-called zero average contrast conditions, which cancel the structure factor contribution to the scattered intensity, allowing us to obtain direct information on the single particle size and structure as particles a

There is still a lack of pharmacological treatment options for traumatic brain injury (TBI), the dominant cause of death and disability in persons under the age of 40 in the developed part of the world. Clinical TBI is a markedly complex disease, categorized into different subtypes that differ in their pathophysiology, treatment requirements, and long-term consequences. For successful development

This paper studies the impact of railroads on growth and structural transformation in 19th-century Sweden. To establish causality, the analysis exploits that the main state-owned lines of the network traversed rural communities that were not directly targeted by planners. Areas “accidentally” traversed by one of these trunk lines experienced substantially more rapid population growth and structura

Research Highlights: When investigating the sorption of water on lignocellulosic materials, the sorption or mixing enthalpy is an interesting parameter that, together with the sorption isotherms commonly measured, can be used to characterize and understand the sorption process. We have compared different methods to assess these enthalpies. Additionally, we propose a sorption nomenclature. Backgrou

The risk of patients committing violence implies major challenges throughout the care process in forensic psychiatry and brings risk assessments to the fore. The aim was to explore nurses’ experiences of risk assessments for their care planning and risk management in forensic psychiatry. Data were collected through focus groups with 15 nurses. The qualitative content analysis followed a deductive

Cleaning workers are exposed to many risk factors, including handling of cleaning products. Epidemiological studies show that they have a high incidence of asthma and other respiratory symptoms. Some studies have indicated an even higher incidence of asthma in individuals using cleaning sprays regularly. It is known that sprays produce an aerosol that can expose the respiratory system to chemicals

Patient organisations contribute to many areas of pharmaceutical policy. In developing their organisational capacity, many turn to financial support from pharmaceutical companies, which may create conflicts of interests. However, the transparency of the industry’s self-regulatory approach to the disclosure of payments to patient organisations has evaded scrutiny. Using company reports disclosing p

Background: Evidence-based recommendations are lacking for prosthetic and orthotic services in low- and lower-middle-income countries. Objectives: The aim of this study was to compare and synthesise findings related to experiences of prosthetic and orthotic service delivery in Tanzania, Malawi, Sierra Leone and Pakistan from the perspective of local professionals. Study design: This is a qualitati

Introduction: Balancing Everyday Life (BEL) is a new lifestyle intervention for mental health services users, developed to support meaningful engagement in daily activities and a balanced lifestyle. This study aimed at exploring the BEL participants’ process of making lifestyle changes. Methods: This constructivist grounded theory study took place in Sweden from 2013–2017 and explored the processe

This thesis investigates the distribution of superconductivity in a Type-II planar, bounded, and smooth superconductor submitted to a piecewise-constant magnetic field with a jump discontinuity along smooth curves---the magnetic edge. This discontinuous case has not been treated before in the mathematics literature, where the considered applied magnetic field is usually assumed to be smooth.We exa

The influence of the co-solutes TMAO, urea, and NaCl on the hydration repulsion between lipid membranes is investigated in a combined experimental/simulation approach. Pressure-hydration curves obtained via sorption experiments reveal that the repulsion significantly increases when the membranes are loaded with co-solutes, most strongly for TMAO. As a result, the co-solutes retain additional water

Idag bedrivs musikforskning inom ett flertal områden. Avsikten med denna panel, med medverkande från disciplinerna musikvetenskap, musikpedagogik och konstnärlig forskning, är att perspektivisera och diskutera förutsättningar och möjligheter för interaktion, samverkan och kunskapsutbyte på fältet som helhet.En central fråga i detta sammanhang rör hur kunskap och utvecklingserfarenheter

Accurate and efficient measurement techniques are needed for exposure assessment of 5G portable devices---which are expected to utilize frequencies beyond 6 GHz---with respect to the radio frequency electromagnetic field exposure limits. Above 6 GHz, these limits are expressed in terms of the incident power density, thus requiring that the electromagnetic fields need to be evaluated with high prec

Växtätare kan påverka ekosystemprocesser, dels genom långsiktiga förändringar av växtsamhällets sammansättning, men också på kortare sikt genom derasmatspjälkning av organiskt material som cyklas genom markens nedbryderorganismer och tillbaka till de primära producenterna. Särskilt störreväxtätare har studerats i stor utsträckning, men i vissa ekosystem som skogar kan de mindre ryggradslösa växtätHerbivory can influence ecosystem processes, partly through long-term changes of the plant community compositions, but also more rapidly through the herbivores’ digestive alteration of the organic matter that is cycled through the soil and back to the primary producers. In the Subarctic mountain birch (Betula pubescens ssp. czerepanovii) forest (SMBF) in Northern Fennoscandia, outbreaks by the geo

Nonstoichiometric protic ionic liquids have recently gained interest because proton acceptors are crucial in the electrolyte of many electrochemical applications such as fuel cells, proton batteries and supercapacitors. In the present work we have prepared and studied several protic poly(ionic liquid)s doped with acid in nonstoichiometric amounts. The poly(ionic liquid)s were based on polydimethyl