Are peroxisome proliferator-activated receptors involved in skeletal muscle wasting during experimental cancer cachexia? : Role of beta2-adrenergic agonists
Implantation of the Yoshida AH-130 ascites hepatoma to rats resulted in a decrease in muscle weight 7 days after the inoculation of the tumor. These changes were associated with increases in the mRNA content for both peroxisome proliferator-activated receptor (PPAR) gamma and PPAR delta in skeletal muscle. The increase in gene expression for these transcription factors was related to increases in
