In patients with airflow limitation caused by cigarette smoking, lung density measured by computed tomography is strongly correlated with quantitative pathology scores of emphysema, but the ability of lung densitometry to detect progression of emphysema is disputed. We assessed the sensitivity of lung densitometry as a parameter of disease progression of emphysema in comparison to FEV1 and gas tra

A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. W

Disease-specific epitope profiles of glutamic acid decarboxylase (GAD)65 autoantibodies (GAD65Ab) were studied in slowly progressive type 1 (insulin-dependent) diabetes mellitus (SPIDDM) and acute onset type 1 (insulin-dependent) diabetes mellitus (AIDDM) using seven kinds of GAD65/67 chimeric molecules. Sera obtained from Japanese SPIDDM (n = 17) and AIDDM (n = 46) patients followed prospectively

Synthesis of mediators of fever, pain and inflammation as well as protection against reactive molecules and oxidative stress is a hallmark of the MAPEG superfamily (membrane associated proteins in eicosanoid and glutathione metabolism). The structure of a MAPEG member, rat mictosomal glutathione transferase 1, at 3.2 angstrom resolution, solved here in complex with glutathione by electron crystall

Analys av den amerikansk high school-filmen under 1980- och 1990-talen

The standardization and clinical validation of the measurement of beta-amyloid(1-42) (Abeta42) in cerebrospinal fluid (CSF), plasma and urine is described using a commercially available sandwich-type ELISA with 21F12 and 3D6 as monoclonal antibodies. The INNOTEST beta-amyloid(1-42) allows the specific and reliable measurement of(1-42) amyloid peptides in CSF and plasma. The Abeta42 concentrations

Breeding success and adult survival of Redshank Tringa totanus on coastal meadows on Gotland, SE Sweden, was investigated in 1997–2003. Two periods with different breeding success could be detected. In 1997–1999, nest success varied between 43 and 64%. Chick survival was not studied in these years. In 2000–03, nest success was lower and varied between 6 and 20%. Survival of chicks from hatching to

We prove several results on holomorphic harmonic morphisms between Hermitian manifolds. In the non-compact case, we find conditions on holomorphic maps from domains in C-2 to C to retain the harmonicity when the metric is conformally changed. We conclude that there are no non-constant harmonic morphisms from S-4 minus a point to a Riemann surface. As for the compact case, we show that holomorphic

Acquired brain injuries can lead to cognitive, emotional as well as behavioural sequelae and can have a great impact on the affected person and his or her family. Over the last decade, pharmacological treatment has become an important part of brain injury rehabilitation. There is increasing clinical experience of the use of various drugs affecting neurotransmitters and cerebral function, but the s

We are increasingly dependent on Internet as a large aspect of our daily life is now handled via online applications. Recent years we have seen several large-scale crises. This has made crisis-related research on Internet applications important. We need the applications to be available at any time, so there is a need to increase availability during heavy overload, both in crises and during normal

OBJECTIVE: To analyze the extent of tumor necrosis factor-alpha (TNFalpha) and TNFbeta gene polymorphism in patients with AD and to relate it to intrathecal levels of these cytokines. METHODS: Analyses of TNFalpha and TNFbeta gene polymorphism were performed using PCR in 52 patients with AD and in 25 control subjects, and the levels of corresponding cytokines were analyzed using ELISA. RESULTS: Pa

Popular Abstract in Swedish Avhandlingen innehåller sju artiklar. Här presenteras ett nytt koncept för att beskriva hur fukt transporteras i porösa material. Detta bygger på införandet av en äkta flödespotential, Kirchhoff's potential. Betraktelsesättet täcker hela processen från mätning av materialdata till numerisk beräkning av fukttransport. Modeller för beräkning av fuktinträngning vid stegäThe work presented in this thesis is focused on the development of the new concept to describe isothermal moisture transport using Kirchhoff potentials. The first four papers deal with moisture transport in porous media using Kirchhoff potentials. The last three papers deal with wood. Here the theory is extended to the case of anisotropic moisture transport. The seven papers have the following con