Cysteine proteases (CPs) are responsible for many biochemical processes occurring in living organisms and they have been implicated in the development and progression of several diseases that involve abnormal protein turnover. The activity of CPs is regulated among others by their specific inhibitors: cystatins. The main aim of this review is to discuss the structure-activity relationships of cyst

This study explores boundary-crossing networks in fuel-cell science and technology. We use the case of Norwegian fuel cell and related hydrogen research to explore techno-science networks. Standard bibliometric and patent indicators are presented. Then we explore different types of network maps-maps based on co-authorship, co-patenting and co-activity data. Different network configurations occur f

In this article we present a downscaled laboratory setup emulating five natural guide stars, a layered static atmosphere and a 7.5-m aperture telescope equipped with dual-conjugate adaptive optics at a wavelength of 2.2 mum. Three reconstruction alternatives were evaluated; conventional adaptive optics, field-averaged conventional adaptive optics and dual-conjugate adaptive optics. The results wer

Abstract is not available

The objective of the present experiments was to study mechanisms governing cerebrovascular responses during severe hypoglycemia, and in the posthypoglycemic recovery period. To that end, lightly anesthetized (70% N2O) and artificially ventilated rats were injected with insulin so as to abolish spontaneous EEG activity for 15 or 30 min ("coma"). In separate animals, recovery was induced by glucose

A study on diffusion measurements of the protein lysozyme in liquids and agarose gels, at different pH and ionic strengths, has been performed using holographic laser interferometry. The measurements showed that the diffusive flux was very dependent on pH and ionic strength when the protein was not at its isoelectric point or when the charge of the lysozyme molecules was not screened by ions in th

The fermentability of indigestible carbohydrates and content of short-chain fatty acids along the hindgut of rats were investigated using plant materials of importance in the Swedish diet (instant potato powder, apples and oat flakes). Results with the composite food products were compared with commercial fibre fractions obtained from similar sources, ie potato fibre, apple pectin and beta-glucan-

Abstract is not available

Structural and electronic properties of TiO2 nanoparticles sensitized with a set of RuII(tpy)(2) based dyes have been investigated using density functional theory (DFT) calculations combined with time-dependent (TD) DFT calculations. The effects of carboxylic and phosphonic acid anchor groups, as well as a phenylene spacer group, on the optical properties of the dyes and the electronic interaction

[abstract missing]

Serum samples were collected from healthy blood donors in 5 regions in Sweden in 1999, i.e. from the local Blood Centres (collecting facilities) in Boden, Jonkoping, Lund, Skovde, and Uppsala. In total, 498 serum samples (63% males, 37% females) were received and tested by immunofluorescence assay for antibodies against B. elizabethae, B. grahamii, B. henselae (Houston-1), B. henselae (Marseille),

Review of Mats Burströms book Samtidsarkeologi. Introduktion till ett forskningsfält.

Objective and Background. To evaluate risk factors for shoulder dystocia and brachial plexus injury using a case-control study at the departments of obstetrics and gynecology at the four largest hospitals in southern Sweden. All cases of shoulder dystocia between 1987 and 1993 inclusive were identified. For each case, two control infants with similar birthweight (+/- 100 g) and identical year of b

OBJECTIVE: In 17 patients with chronic sinusitis persistent after sinus surgery, long-term, low-dose erythromycin therapy was tested. The aim of the investigation was to study the clinical outcome and effects on nasal nitric oxide (NO), ciliary beat frequency (CBF), and mucociliary transport (saccharine transit time). STUDY DESIGN AND SETTING: We conducted a prospective open study at a tertiary te

We used a mass spectrometry-based assay for identifying the endotoxin (lipopolysaccharide, LPS) marker (R)-3-hydroxytetradecanoic acid in cigarette smoke particles and found that smoking involved inhalation of 17.4 pmol of endotoxin per each smoked cigarette. Indoor exposure to environmental tobacco smoke (ETS) entailed inhalation of 12.1 pmol of LPS/m3 air, an amount that was 120 times higher tha