We have investigated the role of lipid metabolism with regard to beta-cell function and insulin secretion. Lipids are known to play a crucial functional role in the pancreatic beta-cell, where they are essential for adequate hormone release, but may also exert a long-term toxic effect, leading to beta-cell dysfunction. Our studies in mice, where insulin resistance and glucose intolerance was induc

By providing the Lund Model fragmentation process with a quantum-mechanical framework we extend the results of previous work to situations where there are very many identical bosons. We investigate the features of the weight distributions in some detail and in particular exhibit three-particle BE-correlations, the influence on the rho-spectrum and the difference between charged and neutral pion co

Popular Abstract in Swedish Nedisningar under Weichsel-istiden kring floden Notec i nordvästra Polen. Inlandsisar är en viktig komponent i jordens klimatsystem. Deras utbredning och rörelsemekanismer styrs till stor del av klimatet samtidigt som isarna i sin tur också påverkar klimatsystemet. Genom kunskap om hur inlandsisarna växte till och smälte av under den senaste istiden kan man utvärdera oThis thesis presents results of studies on the ice flow pattern and ice movement mechanism during the Weichselian glaciations in the middle Notec River area, NW Poland. A new lithostratigraphy of the study area has been established, based on correlation of stratigraphical position, clast lithology, fabrics and grain size composition of till units. The lithostratigraphy covers two glacial advances

Questions: How will density-dependent and costly dispersal evolve in populations subject to local density regulation and environmental stochasticity? What type of density response will evolve, a strong threshold type response or a soft response gradually increasing dispersal? Method: An individual-based model including density dependence, environmental fluctuations, and population variation was us

Sivar Arnér tar i sitt tidiga författarskap (1943–56) upp frågor och motiv som liknar existentialismens: främlingskapet inför världen, de absurda handlingarna, den starka livsviljan och insikten att världen är ett kaos. I samtliga verk från fyrtio- och femtiotalet, även de hörspel som har ett politiskt budskap, beskriver han människor som kämpar med en svår livssituation. Oftast hakar de upp livsm

The utilisation of biofuels is attracting growing support from the European Union and member states as a strategy to tackle climate change, enhance energy security, and contribute to regional development. This paper describes, compares, and analyses the markets for biofuels in Germany and the UK. The introduction of biofuels for transport in these member states provides contrasting pictures, and t

Yearbook of the Swedish Linnaeus Society. Articles on Linnaues and history of biology.

Aggregates of proteoglycans from the Swarm rat chondrosarcoma reassembled in vitro have been studied by rotary-shadowing electron microscopy, and shown to be similar to native structures that have never been dissociated [Morgelin, Engel, Heinegard and Paulsson (1992) J. Biol. Chem. 267, 14275-14284]. A hyaluronate with defined chain length (HAshort) has now been prepared by autoclaving high-Mr hya

OBJECTIVE: The validity of the Ross operation as freestanding root replacement in adult patients with bicuspid aortic valve disease has lately been questioned. We have analyzed retrospectively our results in 23 adult patients (19 males) operated for bicuspid aortic valve disease ad modum "Ross" employing a freestanding root replacement technique. DESIGN: In 9 patients the dominant aortic valve les

Popular Abstract in Swedish Avhandlingens syfte är att kartlägga och analysera hur geografiska visioner utgjort diskursiva redskap i en specifik framtidsorienterad process, institutionaliseringen av Öresundsregionen.This thesis is about how geographical visions worked as discursive tools in the institutionalisation of the Öresund Region. The geographical vision is defined as a cognitive set of imagined and material pictures of the future structured as a spatial whole. The geographical vision is, in addition to this, a spaceconfiguration-, power-, and disciplinary - instrument, and, the product of a discursiv

The internal velocity structure in the Hyades cluster as seen byHipparcos is compared with realistic N-body simulations using the NBODY6code, which includes binary interaction, stellar evolution and theGalactic tidal field. The model allows to estimate reliably the accuracyof astrometric radial velocities in the Hyades as derived by Lindegrenet al. (cite{lindegren00}) and Madsen et al. (cite{madse

A microstructural study of mortars prepared with a low-alkali, low-C3A cement and a Class F fly ash, both of Swedish origin, was carried out using the scanning electron microscopy - energy-dispersive X-ray analytical technique. Supplementary phase analyses were made by X-ray diffraction and thermogravimetry -differential thermal analysis. Normally, CH crystals in the transition zone grow with thei

Resident mouse macrophages secrete Tumor necrosis factor α (TNFα) upon challenge with LPS. The production of TNFα is controlled not only at the transcription of the gene, but also by strong posttranscriptional regulation. When macrophages are stimulated with LPS different signal transduction pathways become activated. Here we show that the combination of the 2 kinases p38 and MEK and presumably ER