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The abnormal accumulation of amyloid-β and tau targets specific spatial networks in Alzheimer’s disease. However, the relationship between these networks across different disease stages and their association with brain connectivity has not been explored. In this study, we applied a joint independent component analysis to18F-Flutemetamol (amyloid-β) and18F-Flortaucipir (tau) PET images to identify
Sin ringa storlek till trots har insekter enorm inverkan på vårt samhälle och våra liv. Bin, som är centrala för att vårt jordbruk ska fungera, har minskat drastiskt i antal de senaste åren. En utbredd bidöd skulle i bästa fall tvinga oss lägga om vår kosthållning markant, och i värsta fall leda till svält. Utöver detta skulle växter som är beroende av bin för sin fortplantning och djur som äter bThis thesis treats entomological lidar from various angles: laboratory reference work on insects of interest, methodological development of lidar- and data processing methods, as well as field implementations of lidar techniques for entomological research. Insects are crucial components of ecosystems and are currently in a global decline. In this thesis, insects are mainly studied in their roles a
Autism spectrum disorders (ASDs) are known to be associated with an increased risk of aggression and challenging behavior. In this study, we have mapped the externalizing history of a nationally representative cohort of young violent offenders with ASD, compared with offenders without ASD. Two hundred and sixty-nine violent offenders were assessed for prevalence of ASD, and participated in a thoro
First-order perturbations of homogeneous and hypersurface orthogonal locally rotationally symmetric class II cosmologies with a cosmological constant are considered in the framework of the 1+1+2 covariant decomposition of spacetime. The perturbations, which are of perfect fluid type, include general scalar, vector, and tensor modes and extend some previous works in which vorticity perturbations we
This paper presents a method to grasp objects that cannot be picked directly from a table, using a soft, underactuated hand. These grasps are achieved by dragging the object to the edge of a table, and grasping it from the protruding part, performing so-called slide-to-edge grasps. This type of approach, which uses the environment to facilitate the grasp, is named Environmental Constraint Exploita
Two-Higgs-doublet models (2HDMs) with a flavored U(1)′ gauge symmetry are a popular extension to the Standard Model (SM), yet they currently lack a complete survey. In this paper, we present a full classification of anomaly-free 2HDMs within the SM fermion content, resulting in a total of 11 distinct models. Four of these are relatively well studied, while the rest either partially, or entirely, l
We combine droplet epitaxy with low-energy electron microscopy imaging techniques to map the surface phase diagram of GaAs(001). The phase patterns produced in droplet epitaxy are interpreted using a simple model which links the spatial coordinates of phase boundaries to the free energy. It is thereby possible to gain important information on surface phase stability, based on the observed sequenti
Personalized medicine requires the integration and processing of vast amounts of data. Here, we propose a solution to this challenge that is based on constructing Digital Twins. These are high-resolution models of individual patients that are computationally treated with thousands of drugs to find the drug that is optimal for the patient.
Photosynthetic antenna systems enable organisms harvesting light and transfer the energy to the photosynthetic reaction centre, where the conversion to chemical energy takes place. One of the most complex antenna systems, the chlorosome, found in the photosynthetic green sulfur bacterium Chlorobaculum (Cba.) tepidum contains a baseplate, which is a scaffolding super-structure, formed by the protei
The deep financial crisis of today has created an interest in the financial catastrophes of yesterday. LarsJonung, Research Adviser at DG ECFIN, asks: is the present crisis a rerun of those of the past?
Background: The dGEMRIC (delayed Gadolinium-Enhanced MRI of Cartilage) technique has been used in numerous studies for quantitative in vivo evaluation of the relative glycosaminoglycan (GAG) content in cartilage. The purpose of this study was to determine the influence of pre-contrast T1 and cartilage thickness when assessing knee joint cartilage quality with dGEMRIC. Methods: Cartilage thickness
