Anti-idiotypic antibodies (anti-Id) to autoantibodies are present in several autoimmune diseases and are hypothesized to have regulatory function. Recently we reported the presence of anti-Id to a major type 1 diabetes-associated autoantibody (CAD65Ab) in sera of healthy individuals. Our current assay for the detection of GAD65Ab-specific anti-Id requires the initial removal of anti-Id from the se

Although positive in terms of patient trauma and recovery time, minimally invasive surgery has several technical drawbacks compared with open surgery. The new da Vinci® Surgical System from Intuitive Surgical® offers technical innovations aiming at overcoming these drawbacks and at improving the surgeon’s operating skills, such as the improved 3-D vision, tremor reduction and flexible instruments

Abstract in UndeterminedWhite layer formation is considered as a part of minimum array of parameters characterizing surface integrity of the machined product. The paper is aimed on identification and characterization of white layer generated when finish turning aged Inconel 718 with Al2O3-SiCw ceramic tools under different cutting conditions, tool wear and coolant application. As expected intensit

This article analyses continuity and change of the agrarian doctrine in colonial and postcolonial Malawi. It engages in a classic debate about images and polices concerning African farming. The article argues that the agrarian doctrine must be related to the broader notion of agrarian populism, more specifically to Chayanov's notion of the logic of the peasant family farm. Employing this broader a

Background: Sharing of data about variation and the associated phenotypes is a critical need, yet variant information can be arbitrarily complex, making a single standard vocabulary elusive and re-formatting difficult. Complex standards have proven too time-consuming to implement. Results: The GEN2PHEN project addressed these difficulties by developing a comprehensive data model for capturing biom

Uncontrolled proliferation and the capacity to infiltrate surrounding tissues are two important characteristics of aggressive tumour cells. Previous observations in both colorectal cancer and basal cell carcinoma indicated that infiltrative tumour cell behaviour might be counteracted by a high proliferative activity, suggesting a coordination of these two activities at the cellular level. Here we

The goal of this article is to examine what role literature played for Nicolae Ceaușescu, Romania's political leader between 1965 and 1989. I focus on the period between 1968 and 1974, when the basis was laid for a cultural policy which was to be applied until the end of Ceaușescu's reign in 1989. Such studies are easier to conduct today, when the archives of the Romanian Communist Party have been

We present a spectroscopic study that reveals that the metal-insulator transition of strained VO2 thin films may be driven towards a purely electronic transition, which does not rely on the Peierls dimerization, by the application of mechanical strain. Comparison with a moderately strained system, which does involve the lattice, demonstrates the crossover from Peierls- to Mott-like transitions.

BACKGROUND/OBJECTIVES: Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the Europea

Recension av Sönke Neitzel & Harald Welzer, Soldater - om kamp,dödande och död.

Purpose: The wide heterogeneity in the early growth and metabolism of children born small for gestational age (SGA), both before and during GH therapy, may reflect common genetic variations related to insulin secretion or sensitivity. Method: Combined multiallele single nucleotide polymorphism scores with known associations with insulin sensitivity or insulin secretion were analyzed for their rela

The thesis explores the potential of one way of facilitating and stimulating collaboration in Library and Information Science (LIS), through a specific scientific collaboration activity: creating, sharing and reusing data collection instruments, such as interview guides, questionnaires, and observation protocols. The four studies reported in the thesis can be read as a linear narrative, each study

Background: Proteins can be used in drug delivery systems to improve pharmacological properties of an active substance. Differences in pH between tissues can be utilized in order to achieve a targeted drug release at a specific location or tissue, such as a tumor. The enamel matrix protein amelogenin has a pH dependent solubility profile and self-assemble to form aggregates at neutral pH. This cou

Meteorological data and soil data have been collected at a site in the central Sudan from 2002 to 2012. The site is a sparse savanna in the semiarid region of Sudan. In addition to basic meteorological variables, soil properties (temperature, water content, and heat flux) and radiation (global radiation, net radiation, and photosynthetic active radiation) were measured. The dataset has a temporal

Background. Although the clinical importance of demonstrating the presence of anti-glomerular basement membrane (anti-GBM) antibodies is well established, less is known concerning the clinical utility of measuring the levels of autoantibodies. Two conformational epitopes of anti-GBM antibodies have been defined at residues 17-31 and 127-141 of the alpha 3(IV)NC1 domain of type IV collagen [alpha 3

This paper looks at an important yet little known component of what Chinese Communist Party Chairman Mao Zedong designated the “dictatorship of the masses”—the outsourcing by the supreme state leadership of selected surveillance, inquisitorial, and other violent tasks to what in a different political system would have been regarded as simply members of the public and/or non-governmental organizati