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The crystal structure of staphylococcal enterotoxin H : Implications for binding properties to MHC class II and TcR molecules
The X-ray structure of the superantigen staphylococcal enterotoxin H (SEH) has been determined at 1.69 Å resolution. In this paper we present two structures of zinc-free SEH (apoSEH) and one zinc-loaded form of SEH (ZnSEH). SEH exhibits the conventional superantigen (SAg) fold with two characteristic domains. In ZnSEH one zinc ion per SEH molecule is bound to the C-terminal β-sheet in the region i
Linking Futures across Scales: a Dialog on Multiscale Scenarios
Spectrophotometric methods for the determination of superantigen structure and stability.
Responses to climate change: Exploring organisational learning across internationally networked organisations for development
Branched short-chain fatty acids modulate glucose and lipid metabolism in primary adipocytes
Short-chain fatty acids (SCFAs), e.g. acetic acid, propionic acid and butyric acid, generated through colonic fermentation of dietary fibers, have been shown to reach the systemic circulation at micromolar concentrations. Moreover, SCFAs have been conferred anti-obesity properties in both animal models and human subjects. Branched SCFAs (BSCFAs), e.g., isobutyric and isovaleric acid, are generated
