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Steady-State Calculation vs. Dynamic Energy Simulations during the Early Design Phase

This article uses the steady-state calculation, based on the heating degree-day method, to verify dynamicenergy simulations and estimate a building's heating energy use in early design phases. Utilizing ClimateStudio through Rhinoceros/Grasshopper, this method acts as a control, ensuring reliability of the dynamicmodel's input/output. The simulations were conducted on a single building block with

BioMEL : a translational research biobank of melanocytic lesions and melanoma

Introduction Diagnosing invasive cutaneous melanoma (CM) can be challenging due to subjectivity in distinguishing equivocal nevi, melanoma in situ and thin CMs. The underlying molecular mechanisms of progression from nevus to melanoma must be better understood. Identifying biomarkers for treatment response, diagnostics and prognostics is crucial. Using biomedical data from biobanks and population-

Rise and fall of the giants? : Innovating firms in Sweden, 1890-2016

This study investigates patterns of innovation during two successive industrial revolutions in Sweden. “Genius engineering firms”, such as L M Ericsson, SKF and ASEA (ABB) have dominated narratives about Sweden’s industrial and innovation success. Using new long-term data series of innovation output, 1890-2016, we observe several patterns. First, we document inverted U-shaped patterns during the c

New Antidiabetic Agents for the Treatment of Heart Failure in Hypertensive Patients

The development of newer glucose-lowering drugs for the treatment of type 2 diabetes in recent years, such as the SGLT-2 inhibitors and GLP-1 receptor agonists/analogues with well-documented clinical benefits from large trials, has influenced international guidelines. These drugs are able to reduce both macro- and microvascular events in patients with type 2 diabetes and to prevent worsening of di

Train stations’ impact on housing prices : Direct and indirect effects

Investments in rail are usually expected to improve accessibility for individuals. The value of the additional accessibility is often measured by the impact on housing prices nearby. This paper analyses the City Tunnel in Southern Sweden, a major railway investment that resulted in two new train stations in 2010: the Triangeln and Hyllie train stations. A station may affect housing prices both dir

Integrating shared e-scooters as the feeder to public transit : A comparative analysis of 124 European cities

E-scooter sharing is a potential feeder to complement public transit for alleviating the first-and-last-mile problem. This study investigates the integration between shared e-scooters and public transit by conducting a comparative analysis in 124 European cities based on vehicle availability data. Results suggest that the integration ratios of e-scooter sharing in different cities show significant

Polydopamine functionalized dendritic fibrous silica nanoparticles as a generic platform for nucleic acid-based biosensing

Accurate and rapid detection of nucleic acid sequences is of utmost importance in various fields, including disease monitoring, clinical treatment, gene analysis and drug discovery. In this study, we developed a "turn-on" fluorescence biosensor that enables simple and highly efficient detection of nucleic acid biomarkers. Our approach involves the utilization of 6-carboxyfluorescein modified singl

Detection of Pseudomonas aeruginosa infection using a sustainable and selective polydopamine-based molecularly imprinted electrochemical sensor

Pyocyanin, a redox-active secondary metabolite produced by Pseudomonas aeruginosa, serves as a crucial virulence factor. Detection and quantification of pyocyanin can aid early diagnosis of infection. A selective and sensitive molecularly imprinted electrochemical sensor was constructed by using a green polymerization technique to deposit an ultrathin polydopamine film on an electrode modified wit