Leukocyte infiltration and trafficking during in-flammatory states in the newborn mouse brain
Objective: Inflammation is associated with higher incidence of perinatal brain injury. To better understand the mechanisms behind these injuries, we have studied the immune cell trafficking into the central nervous system (CNS) through the choroid plexus (CP) in the newborn. Meth-ods: Inflammation was induced in newborn mice using two different toll-like receptor ago-nists: PAM3CSK4 (PAM) and lipo