Sökresultat

In older adults, few studies confirm that adequate concentrations of antibiotics are achieved using current dosage regimens of intravenous β-lactam antibiotics. Our objective was to investigate trough concentrations of cefotaxime, meropenem, and piperacillin in older adults hospitalized with infection. We included 102 patients above 70 years of age. Total trough antibiotic concentrations were meas

The legal status of land had important consequences in pre-industrial societies, and Sweden was no different. Here land was broadly divided into the three categories of free-hold, crown land and noble land, which, in turn, were divided into several sub-categories, each with its own legal and practical consequences. In this paper I present, for the first time, a comprehensive dataset for 17 such su

Herein we present our results on the investigation of the influence of external magnetic fields on the anisotropic collective dynamics of core/shell colloidal cubes having a hematite core and silica shell. Owing to the hematite cores, these micrometer-sized particles possess permanent dipole moments, which are at an angle with respect to the long diagonal of the cubes. As a result, they self-assem

A new approach to feedback control design based on optimal control is proposed. Instead of expensive computations of the value function for different penalties on the states and inputs, we use a control Lyapunov function that amounts to be a value function of the optimal control problem with suitable cost design and then study combinations of input and state penalty that are compatible with this v

A search is presented for the production of the Standard Model Higgs boson in association with a high-energy photon. With a focus on the vector-boson fusion process and the dominant Higgs boson decay into b-quark pairs, the search benefits from a large reduction of multijet background compared to more inclusive searches. Results are reported from the analysis of 132 fb−1 of pp collision data at s

Patients suffering from systemic lupus erythematosus (SLE) are at increased risk of developing cardiovascular disease (CVD) and traditional therapies including statins provide insufficient protection. Impaired removal of apoptotic material is a common pathogenic mechanism in both SLE and atherosclerosis and is considered to be a key factor in the development of autoimmunity. Since oxidized LDL and

Introduction: Ankle fractures are commonly treated by open reduction and internal fixation with plate and screws. Unplanned return to theatre is common, in many cases to extract prominent osteosynthesis material from the lateral malleolus as swelling subsides. We hypothesised that patients operated with a posterolateral plate placement on the lateral malleolus would have fewer reoperations, and fe

Malmö fick landets första folkpark redan för 130 år sedan. Idag, på parkens födelsedag, reflekterar tre kulturgeografer över anläggningens historia och dess roll i dåtid, nutid och framtid.

The number of elderlies is increasing but prevalence of malnutrition has been reported. The aim of the study was to determine the significance of short-term nutritional deficiencies in mice. Immune status was assessed through flow cytometry of leucocytes in Peyer’s patches (PP) and mesenteric lymph nodes (MLN), and intestinal microbiota was evaluated by terminal restriction fragment length polymor

Introduction: Monitoring replacement therapy with standard and extended half-life (EHL) products is challenging, since one-stage assay (OSA) and chromogenic substrate assay (CSA) results may differ significantly. Recent recommendations include local validation of each new product with recovery within 20–30%, depending on activity level. Aim: To validate factor VIII (FVIII) activity for monitoring

Många lantbrukare utför frivilliga åtgärder för att gynna miljön. Som kompensation för kostnader och inkomstbortfall får lantbrukarna en miljöersättning. Ersättningen är åtgärdsbaserad, vilket innebär att dess storlek beror på vilken typ av åtgärd det handlar om och dess omfattning. Denna studie undersöker effekten av att istället göra ersättningar resultatbaserade, det vill säga basera dem på hur

Purpose: Improved early diagnosis and determination of aggressiveness of prostate cancer (PC) is important to select suitable treatment options and to decrease over-treatment. The conventional marker is total prostate specific antigen (PSA) levels in blood, but lacks specificity and ability to accurately discriminate indolent from aggressive disease. Experimental design: In this study, we sought t

With the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a need for diagnostic tests has surfaced. Point-of-care (POC) antibody tests can detect immunoglobulin (Ig) G and M against SARS-CoV-2 in serum, plasma, or whole blood and give results within 15 min. Validation of the performance of such tests is needed if they are to be used in clinical practice. In this study, we

This paper presents a novel method for 3D human pose and shape estimation from images with sparse views, using joint points and silhouettes, based on a parametric model. Firstly, the parametric model is fitted to the joint points estimated by deep learning-based human pose estimation. Then, we extract the correspondence between the parametric model of pose fitting and silhouettes in 2D and 3D spac

Background: Earlier attempts to deliver effective lung doses of surfactant by aerosolization were unsuccessful, mostly because of technical shortcomings. We aimed at quantifying the lung deposition of poractant alfa with a new supraglottic delivery system for surfactant atomization in an experimental neonatal model. Methods: The method involved six sedated 1-day-old piglets lying in the lateral de

The pace-of-life syndrome (POLS) hypothesis predicts that behavior and physiology covary with life history. Evidence for such covariation is contradictory, possibly because systematic sources of variation (e.g. sex) have been neglected. Sexes often experience different selection pressures leading to sex-specific allocation between reproduction and self-maintenance, facilitating divergence in life-

In Bolivia climate change and anthropogenic activities such as extensive agriculture, industries and urbanization have increased the groundwater demand and extraction, which is leading to severe stress on groundwater resources in several regions of Bolivia. This research aims to present an overview of different geophysical surveys performed in Valle Alto (central Bolivia), in particular in the Pun

Purpose of the review: Textile dermatitis can sometimes be difficult to diagnose due to the fact that it is difficult to clinically suspect, and when allergic, patch test correctly and advice the patient as to what garments to avoid. Recent findings: The textile fibres as such are rarely the causative agent. Allergic contact dermatitis due to textiles is primarily caused by substances that are use