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Lack of knowledge about how the various drivers of global climate change will interact with multiple stressors already affecting ecosystems is the basis for great uncertainty in projections of future biological change. Despite concerns about the impacts of changes in land use, eutrophication and climate warming in running waters, the interactive effects of these stressors on stream periphyton are
Pancreatic cancer (PC) is a highly fatal cancer with currently limited opportunities for early detection and effective treatment. Modifiable factors may offer pathways for primary prevention. In this study, the association between the Healthy Lifestyle Index (HLI) and PC risk was examined. Within the European Prospective Investigation into Cancer and Nutrition cohort, 1113 incident PC (57% women)
Background: The Movement Disorder Society criteria for progressive supranuclear palsy introduced the category “probable 4-repeat (4R)-tauopathy” for joint clinical diagnosis of progressive supranuclear palsy and corticobasal degeneration. Objectives: To validate the accuracy of these clinical criteria for “probable 4R-tauopathy” to predict underlying 4R-tauopathy pathology. Methods: Diagnostic acc
Critical Infrastructures (CIs) have a vital role in the functioning and development of our modern societies. To accurately understand the potential consequences of critical infrastructure disruptions, dependencies and potential cascading effects between CIs have to be considered in risk governance. As a step towards creating a system-of-systems model of Sweden’s national technical CIs, this paper
While digitalisation is a widespread technological, social and economic process, shaping markets and consumers, not all efforts to produce digitalised smart consumers are successful. The aim of this paper is to explore and explain failures in the digital agencing of consumers. Making use of the market studies literature on consumer agencing, and drawing on an ethnographic study of ethical shopping
Diabetes mellitus (DM) is a worldwide disease that affects 9% of the adult world population and type 2 DM accounts for 90% of those. A common consequence of DM is kidney complications, which could lead to kidney failure. We studied the potential effects of treatment with insulin and the glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide on the diabetic kidney proteome through the use of
We establish the Hasse principle for smooth projective quartic hypersurfaces of dimension greater than or equal to 28 defined over Q.
Our world is changing fast. On one hand, technological developments provide us with new and powerful electronics devices on almost a weekly basis. On the other hand, the end-user of these electronics is now rarely required to actually configure the devices, as everything is automated. This "de-empowerment" of the end-user may be detrimental to the scientific community. This is because the unique c
Background: Prophylactic central neck dissection in patients with papillary thyroid carcinoma is controversial. Sentinel node biopsy might be an adjunct to optimize surgical treatment for these patients. Earlier studies reported inconsistent detection rates and diagnostic value of this technique, and the role of sentinel lymph node biopsy in thyroid cancer needs to be established. Patients and met
When a literary text is translated from a dominated to a dominating language, Yvonne Lindqvist (2018) observes, it generally undergoes a cosmopolitanizing process. Consecrated by the dominating literary culture, the text is lifted up to a transnational level and deemed significant for an international readership. Lindqvist’s observation is confirmed by the English translations of Swedish working-c
Sml1 is a small ribonucleotide reductase (RNR) regulatory protein in Saccharomyces cerevisiae that binds to and inhibits RNR activation. NMR studies of 15N-labeled Sml1 (104 residues), as well as of a truncated variant (residues 50−104), have allowed characterization of their molecular properties. Sml1 belongs to the class of intrinsically disordered proteins with a high degree of dynamics and ver
