Diabetic Vascular Complications & Inflammation - role of NFAT and TNFalpha
Vascular complications of diabetes account for the majority of morbidity and mortality among diabetic patients. Large clinical trials have identified hyperglycemia as a risk factor in the development of diabetic vascular complications. The effects of hyperglycemia on the vessel wall are not fully understood, but chronic vascular inflammation has been implicated to play a major role in the pathogen