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Single postoperative infusion of zoledronic acid to improve patient-reported outcome after hip or knee replacement : study protocol for a randomised, controlled, double-blinded clinical trial

INTRODUCTION: In Sweden, roughly 3000 patients are reoperated each year due to pain and loss of function related to a loosened hip or knee prosthesis. These reoperations are strenuous for the patient, technically demanding and costly for the healthcare system. Any such reoperation that can be prevented would be of great benefit. Bisphosphonates are drugs that inhibit osteoclast function. Several c

Anticipation of COVID-19 Vaccines Reduces Social Distancing

We show that the anticipation of COVID-19 vaccines reduces voluntary social distancing. In a large-scale preregistered survey experiment with a representative sample, we study whether providing information about the safety, effectiveness, and availability of COVID-19 vaccines affects compliance with public health guidelines. We find that vaccine information reduces peoples' voluntary social distan

Non-Manipulable House Exchange under (Minimum) Equilibrium Prices

We consider a market with indivisible objects, called houses, and monetary transfers. Each house is initially occupied by one agent and each agent demands exactly one house. The problem is to identify the complete set of direct allocation mechanisms that can be used to reallocate the houses among the agents. On the one hand, for price equilibrium mechanisms, we show that the only strategy-proof me

Towards climate resilient peace : An intersectional and degrowth approach

How can peace be climate resilient? How can peace and environmental sustainability be advanced simultaneously? To address these questions, I develop a new conceptual and theoretical framework for climate resilient peace through degrowth. This paper calls for stronger consideration of positive conceptualizations of peace and of intersectionality and degrowth in pursuit of peace and resilience. Not

Accountability for State Failures to Prevent Sexual Assault in Evacuation Centres and Temporary Shelters : A Human Rights-Based Approach

This chapter examines the role that legal actors can play in promoting accountability for, and thereby potentially contributing to the reduction in the incidence of sexual assault in situations of disaster displacement, particularly in evacuation centres and temporary shelters. It argues that justice-sector actors can contribute to accountability for and a reduction in sexual assault in evacuation

Childhood-onset of primary Sjögren’s syndrome: phenotypic characterization at diagnosis of 158 children

OBJECTIVESTo characterize the phenotypic presentation at diagnosis of childhood-onset primary Sjögren syndrome (SjS).METHODSThe Big Data Sjögren Project Consortium is an international, multicentre registry using worldwide data-sharing cooperative merging of pre-existing clinical SjS databases from the five continents. For this study, we selected those patients in whom the disease was diagnosed bel

Toward an operational anthropogenic CO2 emissions monitoring and verification support capacity

Under the Paris Agreement (PA), progress of emission reduction efforts is tracked on the basis of regular updates to national greenhouse gas (GHG) inventories, referred to as bottom-up estimates. However, only top-down atmospheric measurements can provide observation-based evidence of emission trends. Today, there is no internationally agreed, operational capacity to monitor anthropogenic GHG emis

Attachment goes to court: child protection and custody issues

Attachment theory and research are drawn upon in many applied settings, including family courts, but misunderstandings are widespread and sometimes result in misapplications. The aim of this consensus statement is, therefore, to enhance understanding, counter misinformation, and steer family-court utilisation of attachment theory in a supportive, evidence-based direction, especially with regard to

Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons

Microglia are activated in many neurological diseases and have been suggested to play an important role in the development of affective disorders including major depression. To investigate how microglial signaling regulates mood, we used bidirectional chemogenetic manipulations of microglial activity in mice. Activation of microglia in the dorsal striatum induced local cytokine expression and a ne

Melatonin Prevents Early but Not Delayed Ventricular Fibrillation in the Experimental Porcine Model of Acute Ischemia

Antiarrhythmic effects of melatonin have been demonstrated ex vivo and in rodent models, but its action in a clinically relevant large mammalian model remains largely unknown. Objectives of the present study were to evaluate electrophysiological and antiarrhythmic effects of melatonin in a porcine model of acute myocardial infarction. Myocardial ischemia was induced by 40-min coronary occlusion in

From pluri-activity to entrepreneurship: Swedish inshore commercial fisheries navigating in the service-oriented economy : Special issue Tourism and fishing

For decades, inshore commercial fisheries of Sweden have declined in the number of fishermen. In parallel, the service economy has gained importance and the growth in tourism is one example. This implicates new conditions for small firms, active in traditional rural industries. While knowledge about the socio-cultural context of small tourism firms is underdeveloped and since policymaking assigns

Comparative Studies of Internet Use: A Review of SSCI-Indexed Journal Articles, 1969–2019

To map out the state of the art of comparative studies of Internet use and recognize the contributions and shortcomings in the current literature, we have used a four-dimension framework to conduct a review of journal articles indexed in the Social Sciences Citation Index (SSCI) in the field of communication studies in the Web of Science core collection between 1969 and 2019. Our findings describe