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A Monolithic Digital Clock-Generator for On-Chip Clocking of Custom DSP's

This paper shows a robust and easily implemented clock generator for custom designs. It is a fully digital design suitable for both high-speed clocking and low-voltage applications. This clocking method is digital, and it avoids analog methods like phase locked loops or delay line loops. Instead, the clock generator is based on a ring counter which stops a ring oscillator after the correct number

Assessment of primary hip osteoarthritis: comparison of radiographic methods using colon radiographs : comparison of radiographic methods using colon radiographs

OBJECTIVE: To compare the reliability of quantitative measurement of minimum hip joint space with a qualitative global assessment of radiological features for estimating the prevalence of primary osteoarthritis (OA) of the hip in colon radiographs.METHODS: All colon radiographs from patients aged 35 or older, taken at three different radiographic departments in Iceland during the years 1990-96, we

A miniaturised electrochemical affinity assay based on a wall-free sample droplet and micro-dispensing of the redox-labelled binding partner

An affinity-assay was developed that is based on the modulation of the diffusion coefficient of a redox-labelled hapten upon complementary recognition of the analyte leading to an increase of molecular weight and hence to a decrease of the diffusion coefficient. The slower diffusion is monitored by means of cyclic voltammetry. In order to demonstrate the feasibility of this assay format, recogniti

Family burden of cardiovascular mortality: risk implications for offspring in a national register linkage study based upon the Malmö Preventive Project.

Objective. To investigate the adjusted relative risk of cardiovascular disease (CVD) events in offspring of parents with cardiovascular mortality before 75 years. Setting. The city of Malmö, Sweden. Design. A follow-up study based on register linkage analyses. Subjects and methods. In the Malmö Preventive Project (MPP), a total of 22 444 men and 10 902 women attended the screening programme bet

The charge capacity of the chemical bond

A bond capacitance is introduced via the LoProp formalism, and the calculated bond capacitances reflects the properties of the corresponding chemical bond remarkably well. It is clearly possible to characterize the properties of the chemical bond with the help of the calculated bond capacitances.

Anti-infective effects o Lactobacilli in the gastrointestinal tract

Antibiotics constitute the dominant treatment of gastrointestinal infections. However, several serious side-effects are associated with extensive use of antibiotics, including spread of bacterial resistance and allergic reactions as well as potential overgrowth of pathogenic bacteria and viruses. On the other hand, there is a growing body of evidence suggesting that certain bacteria, referred to a

Stimulation of the exocrine pancreas via a third CCK-receptor subtype?

The physiological role of the cholecystokinin1 receptor (CCK1R) and the cholecystokinin/gastrin receptor (CCK2R) in the enzyme release from the exocrine pancreas in various mammal species has been debated. Experiments in pigs have indicated that physiological levels of cholecystokinin-33 (CCK-33) elicit pancreatic enzyme release via CCK2Rs located in the gastro-duodenal region. Since gastrin and C

Latitudinal fractionation of polyhrominated diphenyl ethers and polychlorinated biphenyls in frogs in (Rana temporaria)

The flame retardant polybrominated diphenyl ethers (PBDEs) have become ubiquitous environmental pollutants. The environmental distribution of PBDEs is much less studied than that of the polychlorinated biphenyls (PCBs). To compare the environmental fate of the PCBs with their partial substitute, the PBDEs, common frogs (Rana temporaria)were collected along a similar to1500-km-long latitudinal grad

High activity of xylose reductase and xylitol dehydrogenase improves xylose fermentation by recombinant Saccharomyces cerevisiae

Xylose fermentation performance was studied of a previously developed Saccharomyces cerevisiae strain TMB 3057, carrying high xylose reductase (XR) and xylitol dehydrogenase (XDH) activity, overexpressed non-oxidative pentose phosphate pathway (PPP) and deletion of the aldose reductase gene GRE3. The fermentation performance of TMB 3057 was significantly improved by increased ethanol production an

Comparison of predictive accuracy for pathologically organ confined clinical stage T1c prostate cancer using human glandular kallikrein 2 and prostate specific antigen combined with clinical stage and Gleason grade

Purpose: Previously human glandular kallikrein 2 (hK2) has been implicated to predict pathologically organ confined prostate cancer (PCa) in patients with stage T2 disease. Now we evaluated the usefulness of hK2, as measured by 2 entirely different immunoassay designs, to enhance the discrimination of pathologically organ from nonorgan confined clinical stage T1c PCa. Materials and Methods: A cons

Exploring the actinide-actinide bond: Theoretical studies of the chemical bond in Ac-2, Th-2, Pa-2, and U-2

Multiconfigurational quantum chemical methods (CASSCF/CASPT2) have been used to study the chemical bond in the actinide diatoms Ac-2, Th-2, Pa-2, and U-2. Scalar relativistic effects and spin-orbit coupling have been included in the calculations. In the Ac-2 and Th-2 diatoms the atomic 6d, 7s, and 7p orbitals are the significant contributors to the bond, while for the two heavier diatoms, the 5f o