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Mest uppmärksammad politik vinner?

Medieklimatet påverkar inte bara hur politiken kommuniceras utan också vilken politik som formuleras. Kanske är det vi ser i Vita huset medialiseringens logiska slutpunkt: politik som helt underordnad algoritmerna, en ständigt eskalerande reality-show.

Optical tuning of tissue-mimicking copolymer-in-oil gel for multispectral photoacoustic imaging

Background, Motivation, and ObjectiveThe demand for tissue-mimicking materials (TMMs) is increasing alongside the advancement of hybrid imaging such as photoacoustic imaging (PAI). Developing suitable TMMs for PAI is challenging due to the need to mimic both optical and acoustic tissue properties. The TMMs with tunable properties are needed for the calibration of these imaging modalities, as well

Pneumatic tube transport of trastuzumab in IV bags—Effect of headspace and surfactant on subvisible particle formation

In hospitals, IV bags can be prepared in advance for logistical and microbial safety reasons in a compounding unit and then transported to wards. Transport of protein drugs using a pneumatic tube system has been reported to result in high particle levels. In this study, pneumatic tube transport of trastuzumab in saline polyolefin bags was compared to delivery by hospital porters using an electric

Exploring industry stakeholder perspectives on a clinical testbed for evaluating the handling of protein drugs in hospitals

Protein drugs, such as therapeutic antibodies, are complex and require careful handling to maintain their efficacy and quality. Stress factors in hospitals, like temperature variations and mechanical shocks during transport, may negatively impact the stability of protein drugs (e.g. various monoclonal antibodies). The pharmaceutical industry possesses extensive knowledge about their product formul

Particle formation during peristaltic pumping of therapeutic proteins : Hofmeister anions effect

This study reveals specific ion effects on particle formation during peristaltic pumping of a monoclonal Antibody (Antibody A). For this purpose, three anions in the direct Hofmeister series were selected, ranging from the kosmotropic SO42- to the more neutral Cl- and the chaotropic SCN-. Protein particle formation during peristaltic pumping is described primarily as a surface-driven mechanism. Th

Interactions between polysorbate and antimicrobial preservatives in aqueous parenteral products

Biological drugs intended for multidose use normally contain both preservatives and non-ionic surfactants. However, most common preservatives and surfactants in parenteral formulations are considered to be physically incompatible with each other. In this study, the phase separation of polysorbate 20 and polysorbate 80 in the presence of phenolic preservatives is systematically mapped. The observed

Preaching with AI : an exploration of preachers' interaction with large language models in sermon preparation

This study explores how Swedish preachers incorporate AI chats such as ChatGPT into sermon preparation. Based on interviews, chat logs, and sermon manuscripts from six priests in the Church of Sweden, the study uses relevance theory to analyse the preachers' prompting and evaluation strategies. The preachers primarily use large language models (LLMs) for brainstorming and inspiration, critically eThis study explores how Swedish preachers incorporate AI chats such as ChatGPT into sermon preparation. Based on interviews, chat logs, and sermon manuscripts from six priests in the Church of Sweden, the study uses relevance theory to analyse the preachers' prompting and evaluation strategies. The preachers primarily use large language models (LLMs) for brainstorming and inspiration, critically e

Projected changes in near-surface wind speed in the Arctic by a regional climate model

This study investigates seasonal changes in near-surface wind speeds in the Arctic using the regional climate model (RCM) simulations with RCA4 driven by four global climate models (GCMs) CMIP5 under Representative Concentration Pathways (RCP) 4.5 and 8.5 scenarios. In addition, the RCM RCA-GUESS (RCA4 with interactive vegetation dynamics) is used to investigate the role of biogeophysical feedback

Ensemble estimates of global wetland methane emissions over 2000-2020

Due to ongoing climate change, methane (CH4) emissions from vegetated wetlands are projected to increase during the 21st century, challenging climate mitigation efforts aimed at limiting global warming. However, despite reports of rising emission trends, a comprehensive evaluation and attribution of recent changes remains limited. Here we assessed global wetland CH4 emissions from 2000-2020 based

Assessing recovery time of ecosystems in China : insights into flash drought impacts on gross primary productivity

Recovery time, referring to the duration that an ecosystem needs to return to its pre-drought condition, is a fundamental indicator of ecological resilience. Recently, flash droughts – characterised by rapid onset and development – have gained increasing attention. Nevertheless, the spatiotemporal patterns in gross primary productivity (GPP) recovery time and the factors influencing it remain larg

Staging, Accommodating or Caring : Reviewing the Human Labor Involved in Shaping Robots into Agents

This review examines the hidden and invisible labor humans perform to enable robots to function as agents within Human-Robot Interaction (HRI). While robot agency is often framed as internal and autonomous, this perspective overlooks the relational dynamics that sustain robot functionality in real-world settings. Drawing on feminist theory, the review highlights how humans frequently share the res

Statin use and risk of breast cancer among women with benign breast disease : a Danish nationwide cohort study

BACKGROUND: Statins have been suggested to protect against breast cancer risk, but the observational evidence is inconclusive. We examined the association between statin use and breast cancer incidence among women at higher risk of breast cancer due to a history of benign breast disease (BBD).METHODS: Using Danish registries, we identified cancer-free women aged ≥50 years during 1996-2018 with a h

Coherent Phonons, Localization, and Slow Polaron Formation in Lead-Free Gold Perovskite

Lead-free metal halide perovskites are emerging as less-toxic alternatives to their lead-based counterparts. However, their applicability in optoelectronic devices is limited, and the charge transport dynamics remain poorly understood. Understanding photo-induced charge and structural dynamics is critical for unlocking the potential of these novel systems. In this work, ultrafast optical and Raman

Reviews and syntheses : Review of proxies for low-oxygen paleoceanographic reconstructions

A growing body of observations has revealed rapid changes in both the total inventory and the distribution of marine oxygen over the latter half of the 20th century, leading to increased interest in extending oxygenation records into the past. The use of paleo-oxygen proxies has the potential to extend the spatial and temporal range of current records, constrain pre-anthropogenic baselines, provid

Europe in the Postgrowth Era : Towards A sustainable welfare deal

Europe is confronted with a multiple crisis while coming to grips with its colonial legacy. Given the lack of empirical evidence for sufficient absolute decoupling of gross domestic product (GDP) growth from environmental resource use to stay within planetary limits and meet the Paris climate goals, this article argues that it is unavoidable for the European Union (EU) to enter the postgrowth era

Impact of an intervention for osteoarthritis based on exercise and education on metabolic health : a register-based study using the SOAD cohort

OBJECTIVE: This study evaluated the effects of a 6-week osteoarthritis (OA) exercise and education intervention on metabolic health markers, including blood pressure (BP), glycated haemoglobin (HbA1c), high-density lipoprotein (HDL), cholesterol levels and weight in individuals with both OA and diabetes.METHODS: Data originated from the Swedish Osteoarthritis and Diabetes cohort, which is composed

A cosmopolitan invader – Choreutis sexfasciella (Lepidoptera, Choreutidae) – in Cyprus : first record, molecular characterization, and a reared parasitoid

The Banyan Leaf Skeletonizer moth, Choreutis sexfasciella (Sauber, 1902) (Lepidoptera: Choreutidae), is reported from Cyprus for the first time from Ficus microcarpa L.fil. and F. benjamina L. trees in urban areas of Larnaca, Limassol, and Paphos. C. sexfasciella was originally described from the Philippines and has rapidly extended its range in the last five years into several Mediterranean count