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Experimental studies on protein dynamics at atomic resolution by NMR-spectroscopy in solution require isolated 1H-X spin pairs. This is the default scenario in standard 1H-15N backbone experiments. Side chain dynamic experiments, which allow to study specific local processes like proton-transfer, or tautomerization, require isolated 1H-13C sites which must be produced by site-selective 13C labelin
The aim of the user related assessment of the VCC demonstrator’s “Traffic Jam Assist” system was to study trust, usefulness, perceived advantages, disadvantages, acceptance, and willingness to pay for the driver assistance system. The system provides automated speed control and lane keeping. If a lead vehicle is present, the automated vehicle adapts its speed in order to maintain a pre-set time di
The aim of the user-related assessment was to evaluate the effects on driver behaviour, experiences, reactions, expected effects and acceptance of the Highway Automation” system, developed by VW in sub-project 6 of the AdaptIVe IP. The driving functions were developed as level 3 (conditional automation) functions so the driver does not have to monitor the system while driving. The system provides
Since the last decade, development efforts by academia and industry for automated driving functions have increased significantly. Also, the European research project AdaptIVe is looking into this topic. Within AdaptIVe, 21 different automated driving functions for different speed ranges and target areas have been developed. They have been developed in three sub projects (SPs), addressing different
Genome-wide association studies (GWAS) in coronary artery disease (CAD) had identified 66 loci at 'genome-wide significance' (P < 5 × 10 '8) at the time of this analysis, but a much larger number of putative loci at a false discovery rate (FDR) of 5% (refs. 1,2,3,4). Here we leverage an interim release of UK Biobank (UKBB) data to evaluate the validity of the FDR approach. We tested a CAD phenotyp
The rejection of forward jets originating from additional proton–proton interactions (pile-up) is crucial for a variety of physics analyses at the LHC, including Standard Model measurements and searches for physics beyond the Standard Model. The identification of such jets is challenging due to the lack of track and vertex information in the pseudorapidity range | η| > 2.5. This paper presents a n
In aqueous systems with immobilized macromolecules, including biological tissues, the longitudinal spin relaxation of water protons is primarily induced by exchange-mediated orientational randomization (EMOR) of intra- and intermolecular magnetic dipole-dipole couplings. Starting from the stochastic Liouville equation, we have previously developed a rigorous EMOR relaxation theory for dipole-coupl
The Late Neolithic flint daggers of Scandinavia have long fascinated contemporary flintknappers, due to the beauty of some specimens and the presumed skill required to make them. Examination of populations of daggers in museum collections reveals differences in knapping quality. Such differences are commonly ascribed to variations in skill levels on the part of their makers, and high skill is ofte
ATLAS measurements of two-particle correlations are presented for s=5.02 and 13 TeV pp collisions and for sNN=5.02 TeV p+Pb collisions at the LHC. The correlation functions are measured as a function of relative azimuthal angle Δφ, and pseudorapidity separation Δη, using charged particles detected within the pseudorapidity interval |η|2, is studied using a template fitting procedure to remove a "b
The effect of a user’s body on channel characteristics for single user downlink transmission in an urban scenario for the 5th generation (5G) systems is investigated with ray-tracing at 15 GHz and 28 GHz. Three different designs of user equipment (UE) antennas are fabricated and integrated into a mobile phone prototype, and their 3D radiation patterns are measured both with and without
We report on the growth of single crystal InAs NWs on Si/SiOx substrates by chemical vapor deposition (CVD). By adjusting growth parameters, the diameters, morphology, length and the proportion of superlattice ZB InAs NWs (NWs) can be controlled on a Si/SiOx substrate. Our work provides a low-cost route to grow and phase-engineer single crystal InAs NWs for a wide range of potential applications.
Fluorinated spheres with grafted poly(ethylene glycol) (PEG) have been synthesized using a semi-batch emulsion polymerization in which the initiator is fed slowly to the reaction. In this way, PEG-grafted colloidal spheres can be fabricated with varying PEG chain length, different cores and varying degrees of crosslinking. The resulting batches have been characterized using disc centrifuge photose
The present study investigated the relative importance of two explanations behind perceptions of gender discrimination in hiring: prototypes and same-gender bias. According to the prototype explanation, people perceive an event as discrimination to the extent that it fits their preconceptions of typical discrimination. In contrast, the same-gender bias explanation asserts that people more readily
The G-protein-coupled receptors LGR4, LGR5 and LGR6 are Wnt signaling mediators, but their functions in squamous cell carcinoma (SCC) are unclear. Using lineage tracing in Lgr5-EGFP-CreERT2/Rosa26-Tomato and Lgr6-EGFP-CreERT2/Rosa26-Tomato reporter mice, we demonstrate that Lgr6, but not Lgr5, acts as an epithelial stem cell marker in SCCs in vivo. We identify, by single-molecule in situ hybridiza
We demonstrate one-dimensional (1D) electrical modeling of InP nanowire array solar cells. This 1D modeling gives accurate description of the current voltage response even at high surface recombination velocity. The 1D electrical model decreases the simulation time by 3 orders of magnitude compared to a full three-dimensional (3D) model.
Nanowires (NWs) have potential to enable new types of light-emitting diodes (LEDs), which also entail challenges for the development of improved full device simulation models. In this work we calculate the extraction efficiency and emission enhancement in NW array LEDs at different temperatures and couple the results to carrier transport simulations. Our results show that the extraction efficiency
To enable a more detailed analysis of our recent studies of intracavity double diode structures (DDSs), new simulation tools are needed. Such simulation models must account for both charge and photon transport in the studied structures, consisting of optically coupled AlGaAs/GaAs double heterojunction light emitting diode (LED) and GaAs p-n-homojunction photodiode (PD) structure, enclosed within a
