Background: Microseminoprotein-beta (MSP), a protein secreted by the prostate epithelium, may have a protective role in the development of prostate cancer. The only previous prospective study found a 2% reduced prostate cancer risk per unit increase in MSP. This work investigates the association of MSP with prostate cancer risk using observational and Mendelian randomization (MR) methods. Patients

Background: The FreeStyle Libre glucose sensor has caused many cases of allergic contact dermatitis, and isobornyl acrylate (IBOA) in this sensor has been identified as one of the culprit allergens. Objectives: To report on the presence of IBOA in devices produced by Medtronic, namely, Enlite sensor and insulin infusion set Paradigm MiniMed Quick-set. Patients and Methods: Five patients reacting t

Introduction: In the lower urinary tract (LUT) several members of the TRP superfamily are involved in nociception and mechanosensory transduction. Animal studies have suggested a therapeutic potential of some of these channels, including TRPV1, TRPV4, TRPM8, TRPA1, and TRPM4, for treatment of bladder over- and underactivity and bladder pain disorders, but translation of this information to clinica

The current status of crack tip characterizations is reviewed. Several unresolved areas for further research are identified. Singular fields for stationary and moving crack tips in different non-linear materials are reviewed and special emphasis is put on the extension of the region where these fields dominate. The use of path-area integrals, asymptotically elastic crack tips, and crack initiation

At self-similarity the strain history is implicit in and deducible from the strain field at each instance of the loading process. This fact is taken advantage of in a FEM-technique which allows the load to be applied in one single step, only, even when the incremental theory of plastic flow has to be used. Two self-similar problems are solved. Firstly an analytically solvable anti-plane strain craAt self-similarity the strain history is implicit in and deducible from the strain field at each instance of the loading process. This fact is taken advantage of in a FEM-technique which allows the load to be applied in one single step, only, even when the incremental theory of plastic flow has to be used.Two self-similar problems are solved. Firstly an analytically solvable anti-plane strain crac

Elastic—plastic anti‐plane strain problems can be solved by using FEM programs developed for plane stress. The technique does not involve any manipulations with the FEM code, but is merely a matter of specialization and of translation of notation. Two analytically solvable cases are chosen for demonstration.

Crude Distillation Unit (CDU) represents significant challenge for retrofitting and energy optimisation as the most energy intensive consumer in a conventional crude oil refinery. Pinch Technology and its based-methodologies are found primary keys for decades to energy savings in refining industries for a range of common economic-based and environmental objectives or applications. Typical benefits

Linnénätet är tänkt att uppmärksamma historiskt intressanta växtlokaler och fokuserar på lokaler som varit kända sedan före 1850. Även om många av dem ingår i Floraväkteriet, så har det sig att flera av dessa inte är skyddade och några har inte ens varit uppmärksammade. Jan Thomas Johansson och Mariette Manktelow har startat detta projekt om historiska växtlokaler i Sverige, och här följer en pres

Background: The influence of gender on bipolar disorder is controversial and it is unclear if inpatient care differs between men and women. Here, we investigate for gender differences in the inpatient length of stay for Swedes admitted for bipolar disorder and explore other factors that could explain any observed association. Methods: Admission data were extracted from the Swedish National Patient

We present a case of combination of a leadless pacemaker (Micra) and a subcutaneous implantable cardioverter-defibrillator (S-ICD). The patient had a total of nine adequate shock treatments of ventricular fibrillation during 18 months of follow-up after the implantation. The shock treatments did not lead to any alteration in the Micra. All three sensing vectors of the S-ICD worked well. After 18 m

Aims: In this article we explore the moderators of effectiveness of WISEteens (Web-based brief Intervention for SubstancE using teens), a fully automated web-based brief motivational intervention targeting risky substance use among adolescents. Based on previous studies, we examined the differential effects on drinking of sex, readiness to change, self-efficacy, alcohol risk status, and parental m

This paper presents a novel method to calculate the T-matrix for two non-spherical obstacles positioned close to each other, where the individual circumscribed spheres intersect. This is achieved by translating the obstacles coordinate systems, using translation matrices for spherical vector waves. The new circumscribing spheres enables the obstacles to be positioned close to each other. A new tot