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Nostalgia and tourism

For most of the past 300 years, the concept of nostalgia has been regarded as a medical condition. However, since the 1980s, it has become heavily associated with the ‘heritage industry’ and the creation of consumer experiences, especially in a tourism and leisure context. This special issue on nostalgia and tourism aims to encourage and advance the scholarly conversation about the relationship be

Assessing the use of clinical guidelines against domestic violence in southern Sweden : A mixed-methods study

Background and Aim: Domestic violence is a prevalent public health issue. While clinical guidelines and care programs for its identification and handling have been formulated in all administrative regions of Sweden, their degree of implementation is largely unknown. This study aims to assess the implementation of one administrative region's care program, including how it is seen to align with and

Investigating the overlap and predictive validity between Criterion A and B in the alternative model for personality disorders in DSM-5

The Alternative DSM-5 Model for Personality Disorders (AMPD) consists of level of personality functioning (Criterion A) and maladaptive personality traits (Criterion B). The brief scale versions of these are understudied, while often being used by clinicians and researchers. In this study, we wanted to investigate the overlap and predictive validity of Criterion A and B. Participants (N = 253) wer

Clonal evolution and stereotyped sequences of human IgE lineages in aeroallergen-specific immunotherapy

Background: Allergic disease reflects specific inflammatory processes initiated by interaction between allergen and allergen-specific IgE. Specific immunotherapy (SIT) is an effective long-term treatment option, but the mechanisms by which SIT provides desensitization are not well understood. Objective: Our aim was to characterize IgE sequences expressed by allergen-specific B cells over a 3-year

A new animal product free defined medium for 2D and 3D culturing of normal and cancer cells to study cell proliferation and migration as well as dose response to chemical treatment

Cell culturing methods are increasingly used to reduce and replace the use of live animals in biomedical research and chemical toxicity testing. Although live animals are avoided when using cell culturing methods, they often contain animal-derived components of which one of the most commonly used is foetal bovine serum (FBS). FBS is added to cell culture media among other supplements to support ce

Requirements Engineering for Automotive Perception Systems : An Interview Study

Background: Driving automation systems (DAS), including autonomous driving and advanced driver assistance, are an important safety-critical domain. DAS often incorporate perceptions systems that use machine learning (ML) to analyze the vehicle environment. Aims: We explore new or differing requirements engineering (RE) topics and challenges that practitioners experience in this domain. Method: We

Strength Properties of Wood and Wood-Based Materials

Knowledge of the strength of wood and wood-based materials is an important basis for the calculation and dimensioning of wooden products. This chapter describes the basics of the strength properties, test methods, important influencing parameters (e.g., moisture content, load direction, type of load, duration of load, speed of loading). Phenomenological aspects of failure on various structural lev

Uptake and effectiveness of newer biologic and targeted synthetic disease-modifying antirheumatic drugs in psoriatic arthritis : results from five Nordic biologics registries

Background We aimed to describe the uptake of newer biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) in psoriatic arthritis (PsA) in the Nordic countries and to compare their retention and effectiveness. Methods Patients with PsA starting a b/tsDMARD in 2012-2020 in five Nordic rheumatology registers were included. Uptake and patient characteristics were described,

Free Radical Polymerization of Dimethyl Amino Ethyl Methacrylate Initiated by Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) Macroazo Initiator : Thermal and Physicochemical Characterization

A novel macro intermediate based on poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) was synthesized for use in the copolymerization with dimethyl amino ethyl methacrylate (DMAEMA). Methyl amino ethanol was reacted with PHBHHx to prepare a dihydroxy terminated polyester. The hydroxyl ends of the obtained PHBHHx derivatives were capped with 4,4’-azobis cyanopentanoic acid to obtain the PHBHHx

“You get stuck in it” : Young people's accounts of attempting to quit non-medical tramadol use

Aim: Non-medical use of tramadol and other prescription opioid use has become a great concern in many countries, including Sweden. This study examines key components in young people's accounts of attempting to quit drugs, focusing on non-medical use of tramadol. Methods: Repeated qualitative interviews were conducted with 12 individuals aged 19–24 years with experiences of problems related to non-

Localized Bound Multiexcitons in Engineered Quasi-2D Perovskites Grains at Room Temperature for Efficient Lasers

Reducing the excitation threshold to minimize the Joule heating is critical for the realization of perovskite laser diodes. Although bound excitons are promising for low threshold laser, how to generate them at room temperature for laser applications is still unclear in quasi-2D perovskite-based devices. In this work, via engineering quasi-2D perovskite PEA2(CH3NH3)n-1PbnBr3n+1 microscopic grains

Fountain of youth—Targeting autophagy in aging

As our society ages inexorably, geroscience and research focusing on healthy aging is becoming increasingly urgent. Macroautophagy (referred to as autophagy), a highly conserved process of cellular clearance and rejuvenation has attracted much attention due to its universal role in organismal life and death. Growing evidence points to autophagy process as being one of the key players in the determ

Forensic psychiatric patients’ experiences of participating in administrative court proceedings concerning the continuation of forensic psychiatric care

Introduction: Previous studies show that both staff and patients describe patient participation as a challenge in forensic psychiatry. One reason may be that the forensic psychiatric process is difficult to understand and is experienced as being slow and complex. The proceedings in an administrative court are a core element in forensic psychiatric care as it constitutes the legal authority that le

Adverse events associated with microsurgial treatment for ruptured intracerebral aneurysms : A prospective nationwide study on subarachnoid haemorrhage in Sweden

Background Adverse events (AEs) or complications may arise secondary to the treatment of aneurysmal subarachnoid haemorrhage (SAH). The aim of this study was to identify AEs associated with microsurgical occlusion of ruptured aneurysms, as well as to analyse their risk factors and impact on functional outcome. Methods Patients with aneurysmal SAH admitted to the neurosurgical centres in Sweden wer

Serratus anterior and pectoralis plane blocks for robotically assisted mitral valve repair : a randomised clinical trial

Background: Minimally invasive cardiac surgery provokes substantial pain and therefore analgesic consumption. The effect of fascial plane blocks on analgesic efficacy and overall patient satisfaction remains unclear. We therefore tested the primary hypothesis that fascial plane blocks improve overall benefit analgesia score (OBAS) during the initial 3 days after robotically assisted mitral valve r

Combining target enrichment and Sanger sequencing data to clarify the systematics of the diverse Neotropical butterfly subtribe Euptychiina (Nymphalidae, Satyrinae)

The diverse, largely Neotropical subtribe Euptychiina is widely regarded as one of the most taxonomically challenging groups among all butterflies. Over the last two decades, morphological and molecular studies have revealed widespread paraphyly and polyphyly among genera, and a comprehensive, robust phylogenetic hypothesis is needed to build a firm generic classification to support ongoing taxono

Body descriptions in biohacking and their overlaps and origins : a Swedish case study

This article researches what body descriptions are present within Swedish biohacking, what roots they have, and what overlaps they create between biohacking and other philosophical, political, and scientific discourses. As biohacking has become an increasingly popular subcultural influence in contemporary culture, not least when it comes to individual responsibility for ones health, the aim of theThis article researches what body descriptions are present within Swedish biohacking, what roots they have, and what overlaps they create between biohacking and other philosophical, political, and scientific discourses. As biohacking has become an increasingly popular subcultural influence incontemporary culture, not least when it comes to individual responsibility for ones health, the aim of the