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Kinetics-effect relations of insulin-releasing drugs in patients with type 2 diabetes
Sulfonylureas and glinides have similar mechanisms of action but differ in receptor affinity and binding sites and in absorption and elimination rates. This promotes differences in potency, rate of onset, and duration of action. While prominent in single-dose studies, these differences have less importance during long-term sulfonylurea treatment: at ordinary dosages, rapid- and short-acting (glipi
Dansar med kylskåp
Fotoessä.
Comments on "The role of the human cerebellum in short- and long-term habituation of postural responses".
Effect of near-infrared radiation and jet impingement heat transfer on crust formation of bread
Rapid heat transfer methods can be used to speed up the baking, process and create new product properties. This study investigates the effect of air jet impingement and infrared radiation (alone or in combination) on crust formation of par-baked baguettes during post-baking. The parameters investigated are crust color; crust thickness, total water loss, and heating time. The results show that infr
Medical problems in adolescents with myelomeningocele (MMC): an inventory of the Swedish MMC population born during 1986-1989
Aim: To describe the prevalence of myelomeningocele (MMC) and the medical needs of adolescents, 15-18 years, with MMC in Sweden, at a time when they are on the threshold of adulthood, leaving paediatrics. Methods: In a retrospective study, we identified all adolescents with MMC, born during 1986-1989 and living in Sweden on July 1, 2004. An inventory was agreed upon with questions concerning their
Solvent effects on NMR isotropic shielding constants. A comparison between explicit polarizable discrete and continuum approaches
The gas-to-aqueous solution shifts of the O-17 and C-13 NMR isotropic shielding constants for the carbonyl chromophore in formaldehyde and acetone are investigated. For the condensed-phase problem, we use the hybrid density functional theory/molecular mechanics approach in combination with a statistical averaging over an appropriate number of solute-solvent configurations extracted from classical
Urticarial dermographism: Clinical features and response to psychosocial stress
Studies report that urticarial dermographism is exacerbated by "life events" and emotions. The aim of this study was to determine what aspects of life quality are affected by symptomatic dermographism and whether acute stress is a potential triggering factor. A total of 21 adult patients with urticarial dermographism completed a questionnaire on symptoms and quality of life. Twelve patients agreed
Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual and body composition in 10-12-y-old girls: a 2-y randomized trial
BACKGROUND: Little is known about the relative effectiveness of calcium supplementation from food or pills with or without vitamin D supplementation for bone mass accrual during the rapid growth period. OBJECTIVE: The purpose was to examine the effects of both food-based and pill supplements of calcium and vitamin D on bone mass and body composition in girls aged 10-12 y. DESIGN: This placebo-cont
Hypoxia-induced phenotypic modulation of human neuroblastoma cells
Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING Introduktion Cancer uppstår när en cell i kroppen börjar dela sig okontrollerat, varmed det sker en onaturlig ansamling av celler ? tumörbildning. Solida tumörer t ex bröst- och prostatacancer är till skillnad från ickesolida tumörer som blodcancer/leukemi ofta dåligt försedda med syre på grund av långa avstånd mellan tumörceller ochNeuroblastoma is a childhood tumour derived from cells of the sympathetic nervous system, which are arrested at low differentiation stages. Low differentiation stage and high tumour stage correlate to poor outcome. In earlier studies we have found that hypoxia induces dedifferentiation of neuroblastoma cells, which implies that hypoxia evokes a more aggressive phenotype. Here we employ microarray
Sestamibi Scan-directed Parathyroid Surgery: Potentially High Failure Rate without Measurement of Intraoperative Parathyroid Hormone.
Computationally Efficient Time-Varying ISAR Imaging
By exploiting the relative motion between the target and the radar, high-resolution images of moving targets can be produced using inverse synthetic aperture radar (ISAR). Recent studies have shown that accurate ISAR images can be obtained using the non-parametric high-resolution Capon and APES spectral estimators. In this paper, we propose a computationally efficient time-updating of the two-dime
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Ur Hysteran
Om kvinnlighet och hysteri utifrån den franske psykoanalytikern Luce Irigarays teorier.
Evidence-based nursing, interventions and family nursing: methodological obstacles and possibilities.
Appetite suppression through delayed fat digestion
High-fat diets are often associated with greater caloric intake and weight gain. Since satiety during fat intake is induced by fat in the intestine we investigated the efficiency of a lipid compound that retards fat digestion to regulate fat intake. We found this compound to reduce high-fat food intake, body weight and blood lipids in Sprague-Dawley rats, without causing steatorrhea. The absence o
The impact of canopy exchange on differences observed between atmospheric deposition and throughfall fluxes
To study the impact of canopy exchange on differences observed between atmospheric deposition and throughfall fluxes, several-held experiments were performed at the Speulder forest in The Netherlands. Relevant information was obtained by (i) measuring open-field precipitation and throughfall fluxes with different time resolutions, using two canopy exchange models, (ii) by comparing results from su
Thermodynamics
4-aminobiphenyl-hemoglobin adducts and risk of smoking-related disease in never smokers and former smokers in the European prospective investigation into cancer and nutrition prospective study
The aim of this study was to evaluate whether biomarkers of environmental tobacco smoke exposure [i.e, 4-aminobiphenyl-hemoglobin (4-ABP-Hb) adducts] were predictive of the risk of tobacco-related cancers and diseases. We did a case control study nested within the European Prospective Investigation into Cancer and Nutrition, involving 190 controls and 149 cases (incident cancer of the lung, bladde