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Late neonatal lupus erythematosus onset in a child born of a mother with primary Sjogren's syndrome

Background: The neonatal lupus syndrome can be present as congenital heart block (CHB) or as neonatal lupus erythematosus (NLE), both seldom passively acquired autoimmune diseases. CHB starts around week 20 of pregnancy and is a lifelong event, whereas NLE is self limiting and usually starts at the 6th week of the child's age - the maximum recorded up to week 20. Case report: An asymptomatic mothe

Nature and the Social Sciences : Examples from the Electricity and Waste Sectors

Popular AbstractWhen society first perceived the environmental condition as problematic, focus was on local emissions with local consequences. Subsequently, the center of attention partly moved beyond local effect research to a broader interest in, for instance, ecocycle processes of energy, and the whole lifecycle of materials. However, technological and natural scientific analyses of these phenoThe book has two interrelated objectives. One objective is meta-theoretical and concerns the exploration of theoretical debates connected to issues of studying society and environmental problems; another objective is empirical/analytical, referring to the analysis of "green" public participation in the electricity and waste sectors in Sweden, and partly in the Netherlands as well as the UK. The me

Cardiovascular responses to intravenous calcitonin gene-related peptide (CGRP) in the albino rabbit

The regional sensitivity of different vascular beds to i.v. CGRP was investigated in the albino rabbit by using the microsphere method. Experiments were performed without pre-treatment on both conscious and pentobarbital-anaesthetized animals. In addition, in one series on conscious animals, rabbits were pre-treated with indomethacin in order to reduce the formation of prostaglandins. In another s

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

B cell differentiation is controlled by a complex network of lineage-restricted transcription factors. How perturbations to this network alter B cell fate remains poorly understood. Here we show that classical Hodgkin lymphoma tumor cells, which originate from mature B cells, have lost the B cell phenotype as a result of aberrant expression of transcriptional regulators. The B cell-specific transc

Slutredovisning från projekten "Brandteknisk dimensionering baserad på beräkning" (SBUF) och "Funktionsbaserad brandteknisk dimensionering" (Branndforsk)

This is a summary report of two integrated three year projects "Fire safety design based on calculations" and "Performance based fire safety design". The total project has been subdivided into several part projects: general principles for risk assessment, evacuation safety of public buildings, hotels and health care buildings, calculation of safety factors, calculation of model uncertainties, unce

Valuing Reductions in the Risk of Traffic Accidents Based on Empirical Studies in Sweden

Popular Abstract in Swedish I början av 1990-talet accepterade Vägverket metoden att mäta nyttan av trafiksäkerhet utifrån skattning av enskilda individers betalningsvilja för riskreduktion. Sedan dess har det diskuterats hur man ska gå tillväga för att finna den mest tillförlitliga metoden för att empiriskt mäta individernas betalningsvilja. Syftet med denna avhandling är att beskriva och analyseAt the beginning of the 1990s the Swedish National Road Administration (SNRA) adopted the willingness to pay (WTP) approach for estimating the benefits of safety improvements. However, since then there have been discussions about how to find the most valid and reliable empirical methods to conduct WTP studies. The purpose of this thesis is to describe and analyze approaches used to estimate the va

On the origin of mitochondria: a genomics perspective.

The availability of complete genome sequence data from both bacteria and eukaryotes provides information about the contribution of bacterial genes to the origin and evolution of mitochondria. Phylogenetic analyses based on genes located in the mitochondrial genome indicate that these genes originated from within the f-proteobacteria. A number of ancestral bacterial genes have also been transferred

On the Characteristics of Fires in Tunnels

Popular Abstract in Swedish I avhandlingen presenteras viktiga fenomen i samband med bränder i tunnlar. Detta baseras både på experimentellt och teoretiskt arbete. Tyngdpunkten ligger på de brandförsök i fullskala som genomfördes 2003 i Runehamartunneln i Norge. Under dessa försök mättes brandeffektutvecklingen (HRR), temperaturer, gaskoncentrationer (O2, CO2, CO, HCN och H2O), gashastigheter, strImportant phenomena related to tunnel fires are presented including both experimental and theoretical work. The main focus is on the large-scale fire tests performed in 2003, in the Runehamar tunnel in Norway. During these tests heat release rate (HRR), temperatures, gas concentrations (O2, CO2, CO, HCN, and H2O), velocities, radiation, and smoke were measured. Four tests with a set-up simulating

Hydrothermal alteration of plagioclase and growth of secondary feldspar in the Hengill Volcanic Centre, SW Iceland

Dissolution of igneous feldspar and the formation and occurrence of secondary feldspar in tholeiitic basalts from the Hengill volcanic centre, in SW Iceland was studied by microprobe analysis of cuttings from two ca. 2000 m deep geothermal wells. Well NG-7 in Nesjavellir represents a geothermal system in a rift zone where the intensity of young, insignificantly altered intrusions increases with de