Regional atrophy correlates of domain-specific episodic memory in early Alzheimer’s disease
Alzheimer’s disease (AD) is characterized by amyloid-β (Aβ) and tau depositions as well as neurodegeneration, and is typically accompanied by a progressive decline in episodic memory. Previous research proposes two neural memory networks that process different stimulus domains. Specifically, a posterior-medial (PM) and an anterior-lateral (AL) network handle scene- and object-specific information,