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Radiotherapy to Improve Local Control Regardless of Surgical Margin and Malignancy Grade in Extremity and Trunk Wall Soft Tissue Sarcoma: A Scandinavian Sarcoma Group Study

PURPOSE: Adjuvant radiotherapy has during the past decades become increasingly used in the treatment of localized soft tissue sarcoma. We evaluated the effect of radiotherapy (RT) on local recurrence rates (LRRs) in Scandinavia between 1986 and 2005. METHODS AND MATERIALS: A total of 1,093 adult patients with extremity or trunk wall soft tissue sarcoma treated at four Scandinavian sarcoma centers

A long-term Arctic snow depth record from Abisko, northern Sweden, 1913-2004

A newly digitized record of snow depth from the Abisko Scientific Research Station in northern Sweden covers the period 1913-present. Mean snow depths were taken from paper records of measurements made on a profile comprising 10 permanent stakes. This long-term record yields snow depths consistent with two other shorter term Abisko records: measurements made at another 10-stake profile (1974-prese

Metabolically improved exopolysaccharide production by Streptococcus thermophilus and its influence on the rheological properties of fermented milk

Altered levels of enzymes in the central carbon metabolism in Streptococcus thermophilus increased the exopolysaccharide (EPS) production 3.3 times over that of the parent strain. The influence of enhanced EPS production on the rheological properties of fermented milk is described for engineered strains of S. thermophilus which produce different levels of EPSs.

Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis

The importance of neuropeptide Y (NPY) and Y2 receptors in the regulation of bone and energy homeostasis has recently been demonstrated. However, the contributions of the other Y receptors are less clear. Here we show that Y1 receptors are expressed on osteoblastic cells. Moreover, bone and adipose tissue mass are elevated in Y1(-/-) mice with a generalized increase in bone formation on cortical a

The Verbal Interaction Of Swedish Language-Disordered Preschool-Children

Results are presented from an ongoing project on Swedish pre-school children with language disorders. The aim of the project is to develop clinically applicable methods for the analysis of grammatical and interactional abilities in children. The methods have been tested in a pilot study of ten dialogues between speech therapists and language disordered children. Results indicate that the grammatic

A Phase I/II Evaluation of Metoclopramide as a Radiosensitiser in Patients with Inoperable Squamous Cell Carcinoma of the Lung

The feasibility of administering metoclopramide (MCA) as a radiosensitizer has been evaluated in 23 patients with a pathological or cytological diagnosis of a squamous cell carcinoma of the lung, clinically evaluated as inoperable. All patients received 40-60 Gy radiotherapy fractionated into 1.8 Gy fractions 5 times per week (Monday-Friday). Two MCA treatment regimens were used: (i) MCA at 2 mg/k

Complexation, phase separation, and redissolution in polyelectrolyte-macroion solutions

The complexation, phase separation, and redissolution of polyelectrolyte-macroion solutions have been studied by means of Monte Carlo simulations. A simple model system with focus on the electrostatic interactions has been used to examine the properties of the macroion solutions at different amounts of oppositely charged polyelectrolytes. As oppositely charged polyelectrolytes are added, the stabl

Fuel cell membrane materials by chemical grafting of aromatic main-chain polymers

An extensive world-wide pursuit for new efficient fuel cell membranes materials is currently motivating research on proton-conducting ionomers based on durable aromatic main-chain polymers. In this context, most ionomers. have been prepared either by direct sulfonation of polymers, using for example. fuming. sulfuric-acid, or by direct polymerizations using different sulfonated monomers, Far less

Hokupa'a anisoplanatism and Mauna Kea turbulence characterization

A data set of adaptive optics images has been analyzed in order to study the effects of angular anisoplanatism and to characterize Mauna Kea nighttime turbulence. The data set consists of a selection of Galactic center images obtained with the adaptive optics instrument Hokupa'a and the near-infrared camera QUIRC on the Gemini-North 8 m telescope. Using the Strehl ratio and the FWHM as tracers for

Low temperature anaerobic digestion of mixtures of llama, cow and sheep manure for improved methane production

Biogas production in anaerobic digestion in farm-scale units is typically performed under mesophilic conditions when used for producing domestic fuel and stabilizing animal waste for the use of digested manure as a fertilizer. Previous studies on the digestion of llama and cow manure have shown the feasibility of producing biogas under altiplano conditions (low pressure and low temperature) and of

Bacillus bogoriensis sp nov., a novel alkallphilic, halotolerant bacterium isolated from a Kenyan soda lake

Strain LBB3(T) isolated from Bogoria soda lake in Kenya is an alkaliphilic, Gram-positive, strictly aerobic, non-motile, spore-forming bacterium. It was identified as a member of the genus Bacillus on the basis of phenotypic and phylogenetic analyses. The organism grows optimally at 37 degrees C and pH 10. The G+C content of the genomic DNA is 37.5 mol%. 16S rRNA gene sequence analysis showed 95 a

Integrated bioprocess for the production and isolation of urokinase from animal cell culture using supermacroporous cryogel matrices

An integrated cell cultivation and protein product separation process was developed using a new type of supermacroporous polyacrylamide gel, called cryogel (pAAm-cryogel) support matrix. Human fibrosarcoma HT1080 and human colon cancer HCT116 cell lines were used to secrete urokinase (an enzyme of immense therapeutic utility) into the culture medium. The secreted protein was isolated from the circ

Can An "Estimation Factor" Help Explain Cross-Sectional Returns?

We show in a theoretical model that the expected excess return on any asset depends on its covariance not only with the market portfolio, but also with changes in the representative agent's estimate. We test our model by using GMM and compare it to the CAPM. The results suggest that adding an "estimation factor" to the CAPM helps in explaining cross-sectional returns and that, unconditionally, thi

Leafing phenology and timing of egg laying in great tits Parus major and blue tits P-caeruleus

To evaluate the importance of tree leafing for the start of laying and clutch size of birds, we compared the breeding phenology of great tits Parus major and blue tits P. caeruleus between one coastal and two inland sites in the same geographical region. Because of the cooling influence of the sea, trees at the coastal site were known to initiate budburst about a week later than at the inland site

Diffusion-weighted imaging of brain metastases: their potential to be misinterpreted as focal ischaemic lesions.

Small focal ischaemic brain lesions are said to be easy to identify in the acute stage and to differentiate from older lesions using diffusion-weighted imaging (DWI). Brain metastases are common and the aim of this study was to evaluate the risk of misinterpretation as ischaemic lesions in a standard MRI protocol for clinical stroke. Of 26 patients investigated with MRI for possible metastases, 12

Vertical wrap-gated nanowire transistors

We present a process for fabricating a field-effect transistor based on vertically standing InAs nanowires and demonstrate initial device characteristics. The wires are grown by chemical beam epitaxy at lithographically defined locations. Wrap gates are formed around the base of the wires through a number of deposition and etch steps. The fabrication is based on standard III - V processing and inc