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Background: It has been suggested that carbidopa at high blood concentrations may counter the therapeutic effect of levodopa in Parkinson's disease by entering the brain and blocking central levodopa conversion to dopamine. We previously demonstrated equivalent plasma levodopa concentration in patients with Parkinson's disease during 16 h of (1) intravenous carbidopa/levodopa (DIZ101) infusion, (2

Purpose: Autism Spectrum Disorder (ASD) occurs in 1-1.5% of the general population and possibly in up to 20% of psychiatric outpatients. Post Traumatic Stress Disorder (PTSD) occurs at some point in life in 4% of the general population and in 14–20% of psychiatric outpatients. Knowledge about how PTSD manifests in people with ASD is important in order for it to be correctly diagnosed and intervene

Micromilling is a subtractive manufacturing process that presents challenges due to scale effects and rapid tool wear. To understand the evolution of surface quality when increasing the machined length during the micromilling process, this study assessed the surface roughness, topography, and defects of slots micromilled on Ti-6Al-4V. For the experiments, 1 mm diameter flat end mills were employed

The functional properties of Andean grain starches of two species, amaranth (Amaranthus caudatus) and canihua (Chenopodium pallidicaule), three cultivars each, were studied. The study focused on chemical composition, pasting properties, thermal properties, water solubility index (WSI), swelling power (SP), and granule morphology. All amaranth starches were waxy starches, with amylose content le

Accurate monitoring of daily precipitation is essential for many applications, such as simulation and prediction of watershed water-related disasters. However, precipitation data from satellite and gauge-based precipitation products face challenges in capturing true observations because of their large uncertainties. To improve daily precipitation estimates, this study proposed a new merging framew

Values have been discussed both in relation to the normative character of Ecological Economics and, albeit implicitly, in conceptions of human beings. Nevertheless, a conceptualisation of individually-held values remains underdeveloped. Scholars who do engage on a conceptual level tend to focus on the values of nature in the context of ecosystem services, with less emphasis on: (a) more generally-

Cardiovascular disease (CVD) remains, despite intense research, the most common cause of death world-wide. The main underlying cause of CVD is atherosclerosis, which is characterised by chronic inflammation. CVD and atherosclerosis have a complex aetiology, which necessitates research into multiple areas in order to gain insight into the pathogenesis and find novel markers that could aid in identi

Aims: To examine whether vulvovaginal candidiasis (VVC) precedes type 2 diabetes and to quantify the possible time period between VVC and subsequent diabetes. Material and Methods: We conducted a nationwide retrospective primary healthcare study including 1 838 929 women aged 35–65 years in Sweden (2007–2018). Cox regression models were used to examine associations between VVC and type 2 diabetes,

Objectives: Previous studies found no or weak positive associations between height and lung cancer (LC) risk, with differences between sexes. Few studies stratified the association by smoking status and LC subtype. This prospective study investigated the association between height and risks of overall LC and LC subtypes (i.e., adenocarcinoma, squamous cell carcinoma, small cell carcinoma, large ce

Laminar burning velocities (SL) of di-ethyl ketone (DEK) + air and di-isopropyl ketone (DIPK) + air mixtures were measured using the heat flux method at 305-358 K and equivalence ratios of 0.7–1.4 under atmospheric pressure. Data inconsistency was found between the present SL of di-ethyl ketone + air mixtures and those reported in the literature. Moreover, existing DEK and DIPK combustion kinetic

The development of a model of carbon oxidation has engaged researchers for decades. Yet many outstanding questions remain due to the inability to experimentally study the details of the oxidation. Today, novel techniques such as environmental transmission electron microscopy (ETEM), allowing for in-situ nanoscale observations of the oxidation process, can help illuminate some of these questions. I