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Emerging threats and opportunities to managed bee species in European agricultural systems : a horizon scan

Managed bee species provide essential pollination services that contribute to food security worldwide. However, managed bees face a diverse array of threats and anticipating these, and potential opportunities to reduce risks, is essential for the sustainable management of pollination services. We conducted a horizon scanning exercise with 20 experts from across Europe to identify emerging threats

Simulating Energy Renovation Towards Climate Neutrality. Digital Workflows and Tools for Life Cycle Assessment of Collective Housing in Portugal and Sweden

This chapter compares two digital workflows and tool selection for best practice renovation simulation in Portugal and Sweden. Both workflows are part of ongoing research projects that seek to provide a robust workflow adapted to different user needs and scale implementation. While in Portugal, the focus is on the building, the assessment is scaled up to the neighbourhood in Sweden. Geographic inf

Multivariable prediction models of caries increment : a systematic review and critical appraisal

Background: Multivariable prediction models are used in oral health care to identify individuals with an increased likelihood of caries increment. The outcomes of the models should help to manage individualized interventions and to determine the periodicity of service. The objective was to review and critically appraise studies of multivariable prediction models of caries increment. Methods: Longi

An ultralow-temperature cascade refrigeration unit with natural refrigerant pair R290-R170 : Performance evaluation under different ambient and freezing temperatures

The global demand for ultralow-temperature (ULT) refrigeration units gets greatly promoted, for storage, transportation, and distribution of COVID-19 vaccines. In this work, a ULT freezer is developed with a cascade refrigeration system (CRS) utilizing environmentally friendly refrigerants R290 and R170. The performance of the ULT freezer is experimentally evaluated under different ambient tempera

The rise and fall of the Malvinoxhosan (Malvinokaffric) bioregion in South Africa : Evidence for Early-Middle Devonian biocrises at the South Pole

Global reconstructions, inclusive of environments and ecosystems, and biodiversity counts for the Devonian Period are often done so at the expense of high latitude regions given a historical lack of data presented from these areas. This has bearing on the recognition of biocrises (events marked by extinctions and faunal turnovers) at high latitudes as well as their controls and potential correlati

To what extent are greenhouse-gas emissions offset by trees in a Sahelian silvopastoral system?

To assess the extent to which trees in a semi-arid silvopastoral system (SPS) can offset the greenhouse-gas (GHG) emissions of the system's livestock, this study used two process-based models (STEP-GENDEC-N2O and DynACof) to simulate 9 years of agricultural activity and resulting emissions in a SPS that has been operating in sahelian Senegal. STEP-GENDEC-N2O simulated soil N2O and CO2 fluxes, plus

Diffusion MRI with free gradient waveforms on a high-performance gradient system : Probing restriction and exchange in the human brain

The dependence of the diffusion MRI signal on the diffusion time carries signatures of restricted diffusion and exchange. Here we seek to highlight these signatures in the human brain by performing experiments using free gradient waveforms designed to be selectively sensitive to the two effects. We examine six healthy volunteers using both strong and ultra-strong gradients (80, 200 and 300 mT/m).

Effects of ultra-high field MRI environment on cognitive performance in healthy participants

Introduction: Ultra-high field MRI (UHF MRI) is rapidly becoming an essential part of our toolbox within health care and research studies; therefore, we need to get a deeper understanding of the physiological effects of ultra-high field. This study aims to investigate the cognitive performance of healthy participants in a 7 T (T) MRI environment in connection with subjectively experienced effects.

Care in a Time of Anthropogenic Problems: Experiences from Sanctuary-Making in Rural Denmark

This chapter examines the embodied and situated practices of care in the context of farmed animal sanctuaries in rural Denmark. In approaching care as an “ethical doing,” as suggested by María Puig de la Bellacasa, this chapter asks what kind of alternative images of multispecies life might emerge from sanctuary caregiving in a time of anthropogenic problems? In documenting the difficult task of p

suPARnostic : an advanced predictive tool for detecting recurrence in renal cell carcinoma

Background: Plasma soluble urokinase-type Plasminogen Activator Receptor (suPAR) predicts disease aggressiveness in renal cell carcinoma (ccRCC), but its prognostic accuracy has not been investigated. To investigate the prognostic accuracy of preoperative plasma suPAR in patients who received curative treatment for initially localized ccRCC. Methods: We retrospectively analyzed plasma samples stor

Preliminary evidence that blocking the uptake of placenta-derived preeclamptic extracellular vesicles protects the vascular endothelium and prevents vasoconstriction

Preeclampsia (PE) is a pregnancy syndrome characterized by hypertension and organ damage manifesting after 20 gestational weeks. The etiology is of multifactorial origin, where placental stress causes increased levels of placenta-derived extracellular vesicles (STBEVs) in the maternal circulation, shown to cause inflammation, endothelial activation, vasoconstriction, and anti-angiogenic activity.

Hexavalent chromium still a concern in Sweden - Evidence from a cross-sectional study within the SafeChrom project

OBJECTIVES: Hexavalent chromium (Cr(VI)) is classified as a human carcinogen. Occupational Cr(VI) exposure can occur during different work processes, but the current exposure to Cr(VI) at Swedish workplaces is unknown.METHODS: This cross-sectional study (SafeChrom) recruited non-smoking men and women from 14 companies with potential Cr(VI) exposure (n = 113) and controls from 6 companies without C

In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids

Ventral midbrain dopaminergic neurons project to the striatum as well as the cortex and are involved in movement control and reward-related cognition. In Parkinson's disease, nigrostriatal midbrain dopaminergic neurons degenerate and cause typical Parkinson's disease motor-related impairments, while the dysfunction of mesocorticolimbic midbrain dopaminergic neurons is implicated in addiction and n

Let's Do Free-Spirited Sociology!

Kan du som sociolog bli "bättre" på att teoretisera och i så fall hur? Handlar det om att behärska vissa vetenskapliga metoder för teoretiserande eller tvärtom om att släppa loss och inte tänka så mycket på vad du gör och varför? Är det det ena eller det andra som gäller, eller ska du snarare växla mellan olika förhållningssätt? Måste kreativiteten frigöras och i så fall från vad? I denna korta te

Hydrogen-Bond Acceptor Properties of Nitro-O Atoms : A Combined Crystallographic Database and Ab Initio Molecular Orbital Study

Crystallographic data for 620 C - nitro-O⋯H - N,O hydrogen bonds, involving 560 unique H atoms, have been investigated to the van der Waals limit of 2.62 Å. The overall mean nitro-O⋯H bond length is 2.30 (1) Å, which is much longer (weaker) than comparable hydrogen bonds involving >C=O acceptors in ketones, carboxylic acids and amides. The donor hydrogen prefers to approach the nitro-O atoms in th

Retardation of Aβ42 fibril formation by apolipoprotein A-I and recombinant HDL particles

The double nucleation mechanism of amyloid β (Aβ) peptide aggregation is retained from buffer to cerebrospinal fluid (CSF) but with reduced rate of all microscopic processes. Here, we used a bottom-up approach to identify retarding factors in CSF. We investigated the Aβ42 fibril formation as a function of time in the absence and presence of apolipoprotein A-I (ApoA-I), recombinant high-density lip

Solubility of Foreign Molecules in Stratum Corneum Brick and Mortar Structure

The barrier function of the skin is mainly assured by its outermost layer, stratum corneum (SC). One key aspect in predicting dermal drug delivery and in safety assessment of skin exposure to chemicals is the need to determine the amount of chemical that is taken up into the SC. We here present a strategy that allows for direct measures of the amount of various solid chemicals that can be dissolve