Aim: To examine if there is an association between country of birth in parents and small-for-gestational-age (defined as a birthweight of more than two standard deviations (SDs) below the mean) in first singletons births. Methods: In this follow-up study, national population and healthcare registers were used to identify small-for-gestational-age births in all first singleton births in Sweden betw

The Hippo pathway has recently been implicated in the regulation of organ size and stem cells in multiple tissues. The transcriptional cofactor yes-associated protein 1 (Yap1) is the most downstream effector of Hippo signaling and is functionally repressed by the upstream components of the pathway. Overexpression of YAP1 stimulates proliferation of stem and progenitor cells in many tissues, consis

This paper reports on an empirical comparison of two prominent measures of individual risk attitudes - the Holt and Laury (2002) lottery-choice task and the multi-item questionnaire advocated by Dohmen et al. (2011) - with respect to their within-subject stability over time (one year) and their correlation with actual risk-taking behavior in the lab - here the amount sent in a trust game (Berg et

Planar infrared visualization of species in flames is challenging due to the severe thermal radiation background and relatively weak fluorescence quantum yields from ro-vibration transitions. In this express, we report imaging of molecular species in a flame via an absorption-based coherent optical method, namely infrared polarization spectroscopy (IRPS). Single-shot, planar imaging of hydrogen fl

Autoantibodies against glutamic acid decarboxylase (GAD65Ab) are used in the classification of diabetes in adults. We assessed the concordance in GAD65 autoantibody levels within subjects between three different GAD65Ab radio binding assays (RBA). Plasma samples from 112 diabetes patients (median age 50 years) initially classified with type 2 diabetes was randomly selected from a local diabetes re

Objective: To explore the natural course of knee osteoarthritis (OA) in a middle-aged population with chronic knee pain. Methods: A population-based sample of 143 subjects (mean age 45 (range 35-54), 44% women) with knee pain (>3 months) at inclusion was studied. Weightbearing posteroanterior tibiofemoral (TF) radiographs were obtained at baseline and 12 years later, and classified according to Ke

This work presents an extension, simplification and application of a design procedure for dynamic output feedback design for systems with nonlinearities satisfying quadratic constraints (QC). Our method was motivated by the challenges of output feedback control design for the three-state Moore-Greitzer (MG) compressor model. The classical three-state MG model is a nonlinear dynamical system that i

This paper contains a proposal of new Swedish framework for performance-based design of road tunnel fire safety derived from Swedish and European regulation. The overall purpose of the guideline is to protect life, health, property, environment, and key societal functions from fire. The guideline is structured into five key groups of requirements: #1 Proper management and organisation, #2 to limit

It is well documented that resistance exercise can be performed by patients with breast cancer-related arm lymphedema. The aim of this pilot study was to evaluate the feasibility and safety of a 12-week self-administered weight lifting program for arm and shoulder, and its influence on arm lymphedema status, upper extremity muscle strength, and disability. Twenty-three patients with breast cancer-

The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth

Proteins from halophilic microorganisms thriving at high salinity have an excess of charged carboxylate groups, and it is widely believed that this gives rise to an exceptionally strong hydration that stabilizes these proteins against unfolding and aggregation. Here, we examine this hypothesis by characterizing the hydration dynamics of a halophilic model protein with frequency- and temperature-de

Antimicrobial peptides represent a heterogeneous group that displays multiple modes of action such as bacteriostatic, microbicidal and cytolytic properties that are sequence and concentration dependent. Life threatening infectious disease is now a worldwide crisis and treating them effectively is becoming difficult day by day, due to the emergence of antibiotic resistant strains at alarming rates.

Mitochondrial dysfunction is implicated in neurodegenerative disorders, such as Alzheimer's disease (AD). Translocase of outer mitochondrial membrane 40 (TOMM40) may be influential in this regard by influencing mitochondrial neurotoxicity. Little is known about the influence of the TOMM40 gene on hippocampal (HC) volume and episodic memory (EM), particularly in healthy older adults. Thus, we sough

Objective. This study aimed to assess self-reported well-being in a clinical sample of stroke patients and to identify possible associations with prevalence, severity and bother of lower urinary tract symptoms (LUTS). Material and methods. A cross-sectional, clinical survey was initiated whereby stroke patients were invited to complete The WHO-Five Well-Being Index (WHO-5) and a LUTS instrument, t

The starting point for this study is the transformation that the latest decade has occurred in security and defence affairs. The focal point is the big challenges that these developments have implied for national armed forces. The perspective chosen to describe and analyse this is that of professionalism, and the object of study is that of the Swedish military. The aim of the study is in broad ter

OBJECTIVE - Risk prediction models obtained in samples from the general population do mot perform well in type 2 diabetic patients. Recently, 5-year risk estimates were proposed as being more accurate than 10-year risk estimates. This study presents a diabetes-specific equation for estimation of the absolute 5-year risk of first incident fatal/nonfatal cardiovascular disease (CVD) in type 2 diabet