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Background and Aims: We aimed to compare the risk of frailty in older adults with incident inflammatory bowel disease (IBD) and matched non-IBD comparators and assess the association between frailty and future hospitalizations and mortality. Methods: In a cohort of patients with incident IBD ≥60 years of age from 2007 to 2016 in Sweden identified using nationwide registers, we defined frailty usin

Manipulating light on the nanometer scale is a challenging topic not only from a fundamental point of view, but also for applications aiming toward the design of miniature optical devices. Nanoplasmonics is a rapidly emerging branch of photonics, which offers variable means to manipulate light using surface plasmon excitations on metal nanostructures. As a spectroscopic phenomenon discovered nearl

At their core, the UN Climate Change conferences known as “COPs” are the primary international venue for negotiating how countries should act and cooperate to avoid dangerous climate change. The 2015 Paris Agreement is its most recent notable success. Although the climate negotiations are a state government-led process, the UNFCCC (United Nations Framework Convention on Climate Change) community h

Particles beyond the Standard Model (SM) can generically have lifetimes that are long compared to SM particles at the weak scale. When produced at experiments such as the Large Hadron Collider (LHC) at CERN, these long-lived particles (LLPs) can decay far from the interaction vertex of the primary proton–proton collision. Such LLP signatures are distinct from those of promptly decaying particles t

Guava fruit is rich in phenolic compounds (PCs), whose metabolic fate has not been explored. Non-digestible carbohydrates and PCs in whole guava (WG) and seedless guava (SG) were submitted to an in vitro colonic fermentation, followed by evaluation of the anti-proliferative activity of the fermentation extracts in HT-29 cancer cell lines. The main PCs in both samples were (+)-gallocatechin and gal

We demonstrate a procedure for obtaining a H-intercalated graphene layer that is found to be chemically decoupled from the underlying metal substrate. Using high-resolution x-ray photoelectron spectroscopy and scanning tunneling microscopy techniques, we reveal that the hydrogen intercalated graphene is p-doped by about 0.28 eV, but also identify structures of interfacial hydrogen. Furthermore, we

This work explored the use of pregelatinised amaranth flour (PAF) as an oil substitute in the preparation of amaranth cakes. Amaranth flour was extruded to achieve approximately 50% gelatinisation, ground and sieved. The PAF was used to replace the oil in the cake preparation at levels 33, 66% and 100%. FTIR analysis of the cake formulations showed that PAF modified the molecular organisation of s

Boreal forests have a large impact on the global greenhouse gas balance and their soils constitute an important carbon (C) reservoir. Mature boreal forests are typically a net CO2 sink, but there are also examples of boreal forests that are persistent CO2 sources. The reasons remain often unknown, presumably due to a lack of understanding of how biotic and abiotic drivers interact to determine the

The elliptic flow, v2, of muons from heavy-flavour hadron decays at forward rapidity (2.5

The suppression of chaos in quantum reality is evident in quantum scars, i.e. in enhanced probability densities along classical periodic orbits. They provide opportunities in controlling quantum transport in nanoscale quantum systems. Here, we study energy level statistics of perturbed two-dimensional quantum systems exhibiting recently discovered, strong perturbation-induced quantum scarring. In

hange detection is an important application in remote sensing earth observation which leads to identification of significant environmental events, forest and agricultural landmonitoring. In this paper, we introduce a standalone softwarefor two well-known change detection methods, omnibus test and iteratively re-weighted multivariate alteration detection (IR-MAD). Omnibus test deals with synthetic

Heterostructures of pentacene (PEN) and buckminsterfullerene (C 60 ) are frequently attracting scientific interest as a well-defined small-molecule model system for the study of internal interfaces between two organic semiconductors. They are prototypical representatives forming a donor-acceptor combination for studies of fundamental optoelectronic processes in organic photovoltaics. Despite thei

In this thesis, studies in the chemical synthesis of the dithiodiketopiperazine natural products (—)-glionitrin A and B are described.In Chapter 2, a synthesis of the indoline-fused 2,5-diketopiperazine core of glionitrin A and B using a C-H activation approach is described. The tricyclic core was prepared in only six steps and in a good overall yield (41%). In addition, the synthetic approach was

This article discusses the politics of “direct- action” against fossil fuels put forward by climate justice movements, focusing in particular on the tactic of the blockade. Drawing on the conceptual toolkit of Urban Political Ecology, the argument moves from a critique of the consensual regime of climate change governance to highlight conflict and dissent as central forces for the transformation o

In this commentary we reflect on current labels and criteria for child language impairment from a Swedishperspective. We call for a new label highlighting the developmental, changeable and dynamic characteristics of theimpairment and discuss implications for diagnosis, assessment and research. Conceptual coherence will promotethe professional identity and status necessary for much needed communica

Searches for the lepton number violating decay and the lepton flavor violating and decays are reported using data collected by the NA62 experiment at CERN in 2017-2018. No evidence for these decays is found and upper limits of the branching ratios are obtained at 90% confidence level: , and . These results improve by 1 order of magnitude over previous results for these decay modes.

The NA62 experiment at CERN reports searches for K+→μ+N and K+→μ+νX decays, where N and X are massive invisible particles, using the 2016–2018 data set. The N particle is assumed to be a heavy neutral lepton, and the results are expressed as upper limits of O(10−8) of the neutrino mixing parameter |Uμ4|2 for N masses in the range 200–384 MeV/c2 and lifetime exceeding 50 ns. The X particle is consi

A search for the K+ → π+X decay, where X is a long-lived feebly interacting particle, is performed through an interpretation of the K+ → π+νν¯ analysis of data collected in 2017 by the NA62 experiment at CERN. Two ranges of X masses, 0–110 MeV/c2 and 154–260 MeV/c2, and lifetimes above 100 ps are considered. The limits set on the branching ratio, BR(K+ → π+X), are competitive with previously repor

The NA62 experiment at the CERN SPS reports a study of a sample of 4 × 109 tagged π0 mesons from K+ → π+π0(γ), searching for the decay of the π0 to invisible particles. No signal is observed in excess of the expected background fluctuations. An upper limit of 4.4 × 10−9 is set on the branching ratio at 90% confidence level, improving on previous results by a factor of 60. This result can also be i