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Multinuclear metal active sites are widely used as catalytic reaction centers in metalloenzymes and generally show high catalytic activity. For example, laccases are known to catalyze the oxygen reduction reaction (ORR) to water at a multinuclear copper site with almost no energy loss. The ORR is an important reaction not only in oxygenic respiration but also in future energy generation devices su

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Purpose: The aim of this study was to compare the effects of four months of two types of structured training regimes, static standing (StS) versus dynamic standing (DyS), on passive range of motion (PROM) and spasticity in the hip among non-ambulatory children with cerebral palsy.Method: Twenty non-ambulatory children with cerebral palsy participated in an exercise intervention study with a crosso

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Biographical essay on Märta Strömberg, professor of Archaeology in Lund. She was one of the first female archaeologists that took place in the university world. She became a committed mentor for generations of students, doctoral students and colleagues. Her archaeological investigations of the Stone Age megalithic tombs, the Bronze Age and the Iron Age grave fields and settlements became methodolo

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Combating climate change and transitioning to fossil-free energy are two central and interdependent challenges facing humanity today. Governing the nexus of these challenges is complex, and includes multiple intergovernmental and transnational institutions. This book analyses the governance interactions between such institutions, and explores their consequences for legitimacy and effectiveness. Us

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The introduction first explains the rationale and theoretical and empirical contributions of the edited volume. The book seeks to address a considerable gap of knowledge of the nature of the relationship between institutions governing the climate-energy nexus in a multilevel context. In particular, there is scant research on consequences on the legitimacy and effectiveness of governance arrangemen

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The concluding chapter first summarizes some of the volume’s main results along the four evaluative themes. In terms of coherence and management, the three policy fields under scrutiny – renewable energy, fossil fuel subsidy reform and carbon pricing – are roughly marked by coordination, rather than competition or outright harmony. Regarding legitimacy, the specializations and work backgrounds of

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This chapter establishes four evaluative themes that will be employed across this volume to analyze the institutional complexity of policy fields in the climate-energy nexus: coherence, management, legitimacy, and effectiveness. Coherence among institutions is conceptualized along four dimensions: convergence on an overarching core norm for the policy field, balanced coverage and distribution of m

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This study investigates how related variety in the regional employment mix affects the innovation output of a region. Departing from the idea of recombinant innovation, previous research has arguedthat related variety enhances regional innovation as inter-industry knowledge spillovers occur more easily between different but cognitively similar industries. This study combines a

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Agricultural production systems are affected by complex interactions between social and ecological factors, which are often hard to integrate in a common analytical framework. We evaluated differences in crop production among farms by integrating components of several related research disciplines in a single socio-ecological analysis. Specifically, we evaluated spring barley (Hordeum vulgare, L.)

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Lubricin (PRG4) is a mucin type protein that plays an important role in maintaining normal joint function by providing lubrication and chondroprotection. Improper lubricin modification and degradation has been observed in idiopathic osteoarthritis (OA), while the detailed mechanism still remains unknown. We hypothesized that the protease cathepsin G (CG) may participate in degrading lubricin in sy

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In order to meet the EU's climate and resource efficiency targets, changes in our daily-life behaviours, as well as business models, are urgently necessary. More insights are needed to make real changes based on research with a systems perspective. We developed a system dynamics model to analyse the environmental benefits of a transition from ownership-based to access-based household laundry activ

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Objectives: Cholinergic dysfunction plays a prominent role in cognitive impairment in Parkinson's disease (PD). The aim of this study was to assess the relationship of baseline and longitudinal basal forebrain atrophy with cognitive decline and dementia in PD. Methods: We included 106 non-demented PD patients, 19 PD dementia (PDD) patients and 42 controls with longitudinal structural MRI and cogni

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Ocean Drilling Program (ODP) Site 1051 (Blake Nose, western North Atlantic) is of crucial importance for reconstructing diatom evolution and biosiliceous sedimentation patterns through the early Cenozoic period of extreme greenhouse warmth followed by the progressive global cooling. The magnetostratigraphy in Hole 1051A, however, has been subject to divergent interpretations resulting in multi-mil

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In this paper, an investigation is done into the potential of increasing the coolant temperature of an engine to maximize the powertrain efficiency. The study takes a holistic approach by trying to optimise the combined engine and waste heat recovery system. The work was done experimentally on a Volvo 4-cylinder light duty diesel engine in combination with Rankine cycle simulations. For the study,

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In this study, the effects of fin configurations and layouts on thermal and hydraulic performances of printed circuit heat exchangers (PCHEs) with supercritical liquefied natural gas as the working fluid are studied by a numerical method, and the overall heat transfer performance of various parameters is evaluated by the JF factor. Firstly, the effect of four different airfoil configurations, i.e.

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Aims The aims were to investigate the association between maternal serum levels of perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonate (PFHxS) and perfluorononanoic acid (PFNA) in early pregnancy and overweight in the child at 4 years and to assess potential heterogeneity in exposure effect between strata with different levels of other risk factors for overwe