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The pathological hallmark of Parkinson’s disease is dopaminergic neurodegeneration in the substantia nigra pars compacta neurons and accumulation of α-synuclein containing aggregates in the surviving neurons. The cause of cell death in Parkinson’s disease and the involvement of α-synuclein in the pathophysiology of the disease are unknown. Although other neuronal cell types exhibit α-synuclein pos

The evidence for the existence of a chemical mechanism in surface-enhanced resonance Raman scattering (SERRS) of rhodamine 6G (R6G) adsorbed on colloidal silver excited at 1064 nm is reported on the basis of experimental and theoretical analyses. A weak absorption peak at around 1060 nm for R6G-functionalized silver nanoparticles was observed, which is not present in the individual spectra of R6G

The spatial resolution of fluorescence molecular imaging is a critical issue for the success of the technique in biomedical applications. One important method for increasing the imaging resolution is to utilize multi-photon emissions. In this study, we thoroughly investigate the potential of the multi-photon upconversion emissions from rare-earth-doped upconverting nanoparticles for the improvemen

The nuclear structure of neutron-rich N > 126 nuclei has been investigated following their production via relativistic projectile fragmentation of a E/A = 1 GeV U-238 beam on a Be target. The preliminary analysis indicates the presence of previously unreported isomeric states in the N = 128 isotones Hg-208 and Tl-209.

Even though the mammalian heart has been investigated for many years, there are still uncertainties in the fields of cardiac cell biology and regeneration with regard to exact fractions of cardiomyocytes (CMs) at different developmental stages, their plasticity after cardiac lesion and also their basal turnover rate. A main shortcoming is the accurate identification of CM and the demonstration of

Lina Sandell-Berg. Hennes liv, tro, karriär och livsverk. Feminsitiskt symbolspråk i psalmerna.

Background: Polymorphonuclear neutrophils, stimulated by the activated complement factor C5a, have been implicated in cardiac ischemia/reperfusion injury. ADC-1004 is a competitive C5a receptor antagonist that has been shown to inhibit complement related neutrophil activation. ADC-1004 shields the neutrophils from C5a activation before they enter the reperfused area, which could be a mechanistic a

Purpose - The purpose of this paper is to investigate to what extent male and female PhDs choose academic vs non-academic employment. Further, it analyses gender earnings differences in the academic and non-academic labour markets. Design/methodology/approach - Rich Swedish cross-sectional register data on the stock of PhDs in 2004 is used for investigating differences between male and female PhDs

This study investigates several commercial selective catalytic reduction (SCR) catalysts (A–E) for application in a high-temperature (approximately 525 °C) and high-concentration (5000 ppm NO) system in combination with CO2 capture. The suggested process for removing high concentrations of NOx seems plausible and autothermal operation is possible for very high NO concentrations. A key property of

Recent developments in extremum seeking theory have established a general framework for the methodology, although the specific implementations, particularly in the context of multi-agent systems, have not been demonstrated. In this work, a group of sensor-enabled vehicles is used in the context of the extremum seeking problem using both local and global optimisation algorithms to locate the extrem

Background: Earlier studies have shown an association between secondhand tobacco smoke and allergy development in children. Furthermore, there is an increased risk of developing an allergy if the parents have an allergy. However, there are only few studies investigating the potential synergistic effect of secondhand tobacco smoke and allergic heredity on the development of an allergy. Methods: The

The dinuclear title compound, [FePtCl2(C17H14P)(C23H23NO3P)]x1.25CH2Cl2, has a slightly distorted cis-PtCl2P2 square-planar geometry around the Pt atom, and the ferrocenylphosphine ligands are staggered at an angle of 29.4 (2) deg. about Pt. In the crystal structure, the complex forms centrosymmetric dimers via two strong intermolecular O—H-O bonds resulting in R22(8) rings. A weak intramolecular

This work studies the design of linear precoder codebooks for N-r x N-t MIMO channels with MMSE detection at the receiver. A natural split of precoder-design is unitary precoding and non-unitary precoding. Unitary precoding is only performing rotation of the data in a way beneficial for the channel. Non-unitary precoding additionally also uses power-loading to further improve the performance. Some

Tracking migratory movement of small animals with variable migration patterns is difficult with standard mark-recapture methods or genetic analysis. We used stable hydrogen isotope (delta D) measurements of wings from European red admirals Vanessa atalanta to study several aspects of this species' migration. In the central part of southern Europe we found large differences in delta D values betwee

The Lymphedema Quality of Life Inventory (LQOLI) is an instrument developed for patients with different types of lymphedema. It contains physical, emotional, social, and practical dimensions and consists of 58 items, each with three sub items concerning life quality, daily life changes, and difficulties of changing and two items concerning life quality in general and in relation to lymphedema. The

Agri-environmental schemes have been applied with the goal to mitigate negative effects of agriculture on biodiversity and ecosystem functioning. However, on evaluating the schemes the results have been variable and shown both positive and neutral effects. These variable effects can be attributed to not taking into account important factors affecting the variables at test, such as biodiversity. Th