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This paper presents measurements of charged-hadron spectra obtained in pp, p+Pb, and Pb+Pb collisions at s or sNN = 5.02 TeV, and in Xe+Xe collisions at sNN = 5.44 TeV. The data recorded by the ATLAS detector at the LHC have total integrated luminosities of 25 pb −1, 28 nb −1, 0.50 nb −1, and 3 μb −1, respectively. The nuclear modification factors RpPb and R AA are obtained by comparing the spectr

Measurements of Higgs boson production cross-sections are carried out in the diphoton decay channel using 139 fb−1 of pp collision data at s = 13 TeV collected by the ATLAS experiment at the LHC. The analysis is based on the definition of 101 distinct signal regions using machine-learning techniques. The inclusive Higgs boson signal strength in the diphoton channel is measured to be 1.04−0.09+0.10

Obesity is associated with an increased risk of developing breast cancer (BC) and worse prognosis in BC patients, yet its impact on BC biology remains understudied in humans. This study investigates how the biology of untreated primary BC differs according to patients’ body mass index (BMI) using data from >2,000 patients. We identify several genomic alterations that are differentially prevalent i

Biofuel demand is gradually rising yearly and is expected to do so more rapidly due to the current energy crisis. Bioethanol production is already at a commercial scale but is primarily made using mesophiles fermenting corn and sugar, which have obvious societal drawbacks. Therefore, new technologies should be developed. In addition, hydrogen as a non-carbon energy carrier has gained renewed inter

BackgroundRecovery colleges were developed in England to support the recovery of individuals who have mental health symptoms or mental illness. They have been founded in many countries but there has been little international research on recovery colleges and no studies investigating their staffing, fidelity, or costs. We aimed to characterise recovery colleges internationally, to understand organi

Tourism both contributes to environmental change and is, in turn, affected by such change. One area that is of considerable significance is tourism’s contribution to land use change and its subsequent impacts. Land use change, such as tourism urbanization, together with global heating leads to an increase in surface temperature and deterioration in environmental quality and human comfort levels. U

Measurements of transverse energy-energy correlations and their associated azimuthal asymmetries in multijet events are presented. The analysis is performed using a data sample corresponding to 139 fb −1 of proton-proton collisions at a centre-of-mass energy of s = 13 TeV, collected with the ATLAS detector at the Large Hadron Collider. The measurements are presented in bins of the scalar sum of th

We report the discovery of two warm sub-Neptunes transiting the bright (G = 9.5 mag) K-dwarf HD 15906 (TOI 461, TIC 4646810). This star was observed by the Transiting Exoplanet Survey Satellite (TESS) in sectors 4 and 31, revealing two small transiting planets. The inner planet, HD 15906 b, was detected with an unambiguous period but the outer planet, HD 15906 c, showed only two transits separated

OBJECTIVE: Previous studies have shown that serum levels of testosterone correlate negatively with leptin and positively with insulin-like growth factor binding protein 1 (IGFBP-1). The present study examined whether these associations are linked.DESIGN AND PATIENTS: The association between serum levels of IGFBP-1, free testosterone and insulin on one hand and leptin on the other hand were investi

We recently reported that female patients with hypopituitarism receiving controlled thyroid and steroid hormone substitution, but without GH replacement, had a more than 2-fold increase in cardiovascular mortality compared to the general population. In the present study we investigated the incidence of cardiovascular disease as well as the prevalence of cardiovascular risk factors in 33 females wi

BACKGROUND: Contact allergy rates of linalool and limonene hydroperoxides (HPs) have increased.OBJECTIVES: To demonstrate the patterns of simultaneous positive patch test (PT) reactions and prevalences of multiple contact allergies (MCAs) in patients with contact allergy to linalool and/or limonene HPs.METHODS: A retrospective analysis of consecutive dermatitis patients in 2015-2020 was performed.

Background: Allergic contact dermatitis (ACD) caused by hexavalent chromium (Cr(VI)) is often severe and difficult to treat. The content of Cr(VI) in cement can be reduced by, for example, addition of iron(II) sulfate. Since 2005 the content of Cr(VI) in cement is regulated in the EU Directive 2003/53/EC and must not exceed 2 ppm. Since this regulation came into force, ACD caused by cement has

Recently, epidemiological evidence has suggested that hypopituitarism with untreated growth hormone deficiency (GHD) is associated with a high incidence of cardiovascular mortality and that women are particularly at risk. In the present study, the incidence of cardiovascular disease and prevalence of cardiovascular risk factors in 33 such women was assessed and compared with matched controls. A si

BACKGROUND: Contact allergy to the mint-tasting flavour carvone has been observed in patients with oral lichenoid lesions (OLL). Mint-flavoured products such as toothpaste frequently contain carvone. Snuff is a smokeless tobacco product that is chewed or placed in the mouth rather than smoked. In Sweden, the use of snuff and its flavoured versions is extremely common.OBJECTIVES: To investigate whe

OBJECTIVE: Many GH deficient (GHD) patients have impaired glucose tolerance and GH substitution in these patients has caused deleterious effects on glucose tolerance with hyperinsulinaemia. This further impairment of glucose tolerance might be due to an unphysiologically high dose of GH. Whether such a deterioration can be avoided by an optimal GH replacement dose is not known. In most previous st

Patch testing with fragrance allergens has been performed for over half a century, and the protocol has been continually developed and standardised. Fragrance mixes I and II and Myroxylon pereirae resin are commonly used as screening fragrance allergens in patch testing.During the past few decades, linalool and limonene hydroperoxides have emerged as contact allergens as a result of high rates of